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The map label for this gene is etfA [H]

Identifier: 117919854

GI number: 117919854

Start: 1623445

End: 1624371

Strand: Direct

Name: etfA [H]

Synonym: Shewana3_1406

Alternate gene names: 117919854

Gene position: 1623445-1624371 (Clockwise)

Preceding gene: 117919853

Following gene: 117919855

Centisome position: 32.65

GC content: 51.46

Gene sequence:

>927_bases
ATGGCCATTTTAGTATTAGCAGAACACGATAATGCGGCACTGAAACTGGATACCGCAAAGGTTGTCACCGCTGCGTGTGC
CATTGGTGATGATGTGCATGTATTGGTGGTAGGTCACCAATGTGGCGCCGTGGCACAAGCCGCGCAAGCCTTACAAGGTG
TCGCTCAAGTATTAGTCGCCGATAACAGTGCCTATGAAGCGCATTTAGCCGAAAACGTAGCTAAATTGTTGGTGGACTTA
GCACCAAACTACAGCCATATCTTGGCTGCAGCATCGAGCGCTGGCAAAGATACGCTACCACGTGTGGCGGCCTTGTTAGA
CGTTGCGCAAATTTCTGAAGTGATTGGCGTGGTGAGCAGTGATACTTTTGTTCGCCCGATTTACGCGGGTAACGCTTTAG
CGACAGTACAAAGCCATGACGCGATTAAAGTGATGACAGTCCGTGCCAGTGCCTTCGATGCAGCGGCGCAGGGCAACAGT
GCCGCCGTGACCACCTTAGATAAAGTATTTGAAGCCAAAACCCAGTTTGTATCTCAATCATTGACCGTTTCAGCACGTCC
AGAGTTAGGTAATGCGGGCATTATCGTTTCTGGTGGCCGTGGTATGGGCAGCGGTGAAAACTTCGGTATGTTAGAGCAAT
TGGCGGACAAACTCGGTGCCGCGGTTGGGGCTTCTCGCGCCGCGGTTGACGCAGGTTTTGTGCCTAACGATCTGCAAGTG
GGTCAAACCGGTAAGATTGTGGCGCCAAATCTCTACATCGCCGTGGGGATTTCGGGTGCGATTCAGCATTTAGCAGGGAT
GAAAGACGCTAAGGTGATTGTGGCAATCAACAAAGATCCTGAAGCGCCAATCTTCCAAGTGGCCGATTATGGCCTCGAAG
CCGACCTGTTCGACGCCGTTCCAGAGTTGATTTCAACTCTAGGTTGA

Upstream 100 bases:

>100_bases
GGTGAAGGTGACGCCACCTGCCGAACGTAAGGCGGGCATCATGGTTGCGTCGGTAGCTGAGCTGGTTGAAAAGTTAAAGA
ATGAAGCGAAGGTGATCTAA

Downstream 100 bases:

>100_bases
TTTTATCCGTGATCTAAGTCAAAGTAAGCGGCTTTGCGGTGGCAACTGCTTAGCCGCTTATGTTTTTATCTGCCTCACGC
CCGTGCATGGGCGTTCTTAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAILVLAEHDNAALKLDTAKVVTAACAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVADNSAYEAHLAENVAKLLVDL
APNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSSDTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNS
AAVTTLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAVPELISTLG

Sequences:

>Translated_308_residues
MAILVLAEHDNAALKLDTAKVVTAACAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVADNSAYEAHLAENVAKLLVDL
APNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSSDTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNS
AAVTTLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAVPELISTLG
>Mature_307_residues
AILVLAEHDNAALKLDTAKVVTAACAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVADNSAYEAHLAENVAKLLVDLA
PNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSSDTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNSA
AVTTLDKVFEAKTQFVSQSLTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQVG
QTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAVPELISTLG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=310, Percent_Identity=57.741935483871, Blast_Score=334, Evalue=5e-92,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=60.5947955390335, Blast_Score=307, Evalue=9e-84,
Organism=Escherichia coli, GI1787990, Length=259, Percent_Identity=31.2741312741313, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786226, Length=185, Percent_Identity=35.6756756756757, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082157, Length=224, Percent_Identity=30.8035714285714, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=54.0192926045016, Blast_Score=313, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6325261, Length=291, Percent_Identity=45.360824742268, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=60.4501607717042, Blast_Score=348, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=60.4501607717042, Blast_Score=348, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31342; Mature: 31211

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNAALKLDTAKVVTAACAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVA
CEEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
DNSAYEAHLAENVAKLLVDLAPNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSS
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNSAAVTTLDKVFEAKTQFVSQS
CCEEEEEECCCEEEEEECCCCEEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
EEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHCCCCHHHHHHH
PELISTLG
HHHHHHCC
>Mature Secondary Structure 
AILVLAEHDNAALKLDTAKVVTAACAIGDDVHVLVVGHQCGAVAQAAQALQGVAQVLVA
EEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
DNSAYEAHLAENVAKLLVDLAPNYSHILAAASSAGKDTLPRVAALLDVAQISEVIGVVSS
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGNALATVQSHDAIKVMTVRASAFDAAAQGNSAAVTTLDKVFEAKTQFVSQS
CCEEEEEECCCEEEEEECCCCEEEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
LTVSARPELGNAGIIVSGGRGMGSGENFGMLEQLADKLGAAVGASRAAVDAGFVPNDLQV
EEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPNLYIAVGISGAIQHLAGMKDAKVIVAINKDPEAPIFQVADYGLEADLFDAV
CCCCCEECCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHCCCCHHHHHHH
PELISTLG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]