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The map label for this gene is rfbC [H]

Identifier: 117919840

GI number: 117919840

Start: 1607096

End: 1607632

Strand: Direct

Name: rfbC [H]

Synonym: Shewana3_1392

Alternate gene names: 117919840

Gene position: 1607096-1607632 (Clockwise)

Preceding gene: 117919839

Following gene: 117919853

Centisome position: 32.32

GC content: 45.62

Gene sequence:

>537_bases
ATGAAGTGCATTGAAACCGAGCTTGCAGAAGTATTGGTGTTCGAACCTCAAGTTTTTGGTGATGAACGCGGTTTTTTTAT
GGAAACCTTTAGACAATCGTTTTTCTCCGAGTGTTTGAAAAGTAGAGGATTAAAGGTGCAGGAGTTAGTCCAAGATAACT
TTAGCCGATCACAACAACACGTATTACGTGGCTTGCACTACCAACGTGAGCATCCGCAGGGAAAGTTAGTTCGCGTGTGT
GCTGGCAGTATTTTTGATGTCGCTGTGGATATTCGCCCGCAATCTAAAACCTATGGTAAATGGGTAGGGCGTGTGCTCTC
TGCTGATAACCATTTGCAAATGTGGATCCCGCCTAGCTTTGCTCATGGATTTTATGTGTTGAGTGAATATGCCGATGTGC
TTTATCGCTGCACTGATTATTACGCGCCAGATGATGAATATGTGCTGGCATGGAATAGTGCCGAGTTTGCGATTGACTGG
CCGCTGCTAAATGAAACGCCGATTCTGTCTGAAAGGGATGCTGCCGCTAGCGCCTAA

Upstream 100 bases:

>100_bases
GGTTGGATAGATGCTGCGCAGCTTACCGCTTTAGCACAACCTTTGCTTAAAAGCGGTTATGGTGAGTATCTTTTGGGCTT
ATTAAATAAGCAGGTGTTCA

Downstream 100 bases:

>100_bases
GGTACTAGCGGCATTTTGTTTGCGTTATTTGACAGACTCACTTGTGATGCTTGCGCGTGTGAACCAAGGATCTCTAGCAT
CCATTACATCATATAGACTG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSFFSECLKSRGLKVQELVQDNFSRSQQHVLRGLHYQREHPQGKLVRVC
AGSIFDVAVDIRPQSKTYGKWVGRVLSADNHLQMWIPPSFAHGFYVLSEYADVLYRCTDYYAPDDEYVLAWNSAEFAIDW
PLLNETPILSERDAAASA

Sequences:

>Translated_178_residues
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSFFSECLKSRGLKVQELVQDNFSRSQQHVLRGLHYQREHPQGKLVRVC
AGSIFDVAVDIRPQSKTYGKWVGRVLSADNHLQMWIPPSFAHGFYVLSEYADVLYRCTDYYAPDDEYVLAWNSAEFAIDW
PLLNETPILSERDAAASA
>Mature_178_residues
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSFFSECLKSRGLKVQELVQDNFSRSQQHVLRGLHYQREHPQGKLVRVC
AGSIFDVAVDIRPQSKTYGKWVGRVLSADNHLQMWIPPSFAHGFYVLSEYADVLYRCTDYYAPDDEYVLAWNSAEFAIDW
PLLNETPILSERDAAASA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=174, Percent_Identity=54.5977011494253, Blast_Score=184, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17550412, Length=173, Percent_Identity=45.6647398843931, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20524; Mature: 20524

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSFFSECLKSRGLKVQELVQDNFSRSQQH
CCCHHHHHHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VLRGLHYQREHPQGKLVRVCAGSIFDVAVDIRPQSKTYGKWVGRVLSADNHLQMWIPPSF
HHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCH
AHGFYVLSEYADVLYRCTDYYAPDDEYVLAWNSAEFAIDWPLLNETPILSERDAAASA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSFFSECLKSRGLKVQELVQDNFSRSQQH
CCCHHHHHHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VLRGLHYQREHPQGKLVRVCAGSIFDVAVDIRPQSKTYGKWVGRVLSADNHLQMWIPPSF
HHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCH
AHGFYVLSEYADVLYRCTDYYAPDDEYVLAWNSAEFAIDWPLLNETPILSERDAAASA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]