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The map label for this gene is kinB [H]

Identifier: 117919838

GI number: 117919838

Start: 1604737

End: 1606098

Strand: Direct

Name: kinB [H]

Synonym: Shewana3_1390

Alternate gene names: 117919838

Gene position: 1604737-1606098 (Clockwise)

Preceding gene: 117919835

Following gene: 117919839

Centisome position: 32.27

GC content: 44.13

Gene sequence:

>1362_bases
ATGACACGTATGTTAGACAGGATTTTATTCGATGTAAGCCGTTCATCCATTATTGATGGTGGCGATCTTGTTGAGGCCTC
ACAACTTATCGTGACATCTGTGTGCCAAGGGTTAAAAATCACCCGTGCTGGCATTTGGTTATGGAGTGAAGATCACCAAA
GTATGCATTGCTTTTACCTGCTCGATAATATGCACAGGCAAGAGGCGTTGATATTAACTCGGCAGGATTATCCACATTAT
TTCAGTCTATTAGATAATGAGCGCGCTATTGTCGCGAATCATGCGCAAACAGATGGGGCGACCCATGAGTTTGTTAGTGC
CTACTTAGTCCCTAATCGTATTAGTTCTCTGTTAGATAGTCCCATACGTCATCGCGGAAAAATGGTCGGCATTATCTGCT
CCGAGCATCAAGGTGTGCCTCGAGAATGGACGCGTGACGAAAGAGCCTTTGCTTCTGCTTTGGCCGATTTATTCGGCCGA
GCGATGAGCGCAAAGGAAATTTTGGATTATCAGCATCAATTAAAGGCTATTAATGCGGATTTGGAGGTCCAGGTTGAGCA
GCGAACGCAAGAACTTGAAACTGCATTATCGGATTTACGCTCAATACAACACCATTTAGTTGAAAACGAGAAAATGGCGG
CTTTAGGAAGTTTGGTTGCAGGGGTTGCGCACGAGGTCAATACGCCTCTAGGGATTGCCGTGACATCCGTAACCCATTGT
TTAGATGAAGTGGCACTGCTGAAAACGGCTTTTGAGCAAAACGAGTTGGATGAGGATAAATTTTTATCCTTTATCAATAC
CATGCAGGATGGTTTAGGGTTGATTGAGCGCAATCTTTCGCGAGCAGCGGAGTTAGTCCATAACTTTAAGCGCACCGCCG
CAGACCAATCGGTGCTAGAACGTGAGCGGTTTAATTTAAAGACCTATATTTTCCAAATTTTCAGCTCATTAAGGCCGCTA
ATGCGTAAGAAGAATATTGTCTTGAACGTGGAGCTTGATGACGACATCTTTATCGAATCTTACCCTGGTGCCATCGCACA
GATTTTCACTAATTTAGTGGCCAATAGCTTTCGCCATGGATTTCCTGAGAGTTTTACGGGGGATAAAAGCATCACTATTC
GAGTACAAAAACAAGACTCGAACATTTGTATGCAGTATCAAGATAATGGGGTAGGGATGAGCGATGAGGTTAAACTGAAA
GCCTTCGAGCCTTTTTTCACTACCGCACGTAAAGACGGCGGCACAGGTCTTGGTATGTCTATTATTTATAATCTGGTGAC
GCAAAAACTTCATGGCACCATTTTGCTAGCCTCATCCCCAGATCAAGGTGTGAAGGTCGAAATACAGATCCCTGAGAAAT
AA

Upstream 100 bases:

>100_bases
CAGATTGAATCTATACTAAAGAGAACCACTTAAGCTTAGGTCACCAAGTTTATTGCCTCATTTTTAAGTCAGGCGGTACC
ACGCGGGGTAAATCTGCATT

Downstream 100 bases:

>100_bases
GCTTAGATATTGTTTAGGCGACAATGCGATCTTGTTGAAGACCTCGTGCCATTCAGCTTTATCGGCATTTATATGCTACA
ATCATCCCTTCACTTTGACT

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTRMLDRILFDVSRSSIIDGGDLVEASQLIVTSVCQGLKITRAGIWLWSEDHQSMHCFYLLDNMHRQEALILTRQDYPHY
FSLLDNERAIVANHAQTDGATHEFVSAYLVPNRISSLLDSPIRHRGKMVGIICSEHQGVPREWTRDERAFASALADLFGR
AMSAKEILDYQHQLKAINADLEVQVEQRTQELETALSDLRSIQHHLVENEKMAALGSLVAGVAHEVNTPLGIAVTSVTHC
LDEVALLKTAFEQNELDEDKFLSFINTMQDGLGLIERNLSRAAELVHNFKRTAADQSVLERERFNLKTYIFQIFSSLRPL
MRKKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHGFPESFTGDKSITIRVQKQDSNICMQYQDNGVGMSDEVKLK
AFEPFFTTARKDGGTGLGMSIIYNLVTQKLHGTILLASSPDQGVKVEIQIPEK

Sequences:

>Translated_453_residues
MTRMLDRILFDVSRSSIIDGGDLVEASQLIVTSVCQGLKITRAGIWLWSEDHQSMHCFYLLDNMHRQEALILTRQDYPHY
FSLLDNERAIVANHAQTDGATHEFVSAYLVPNRISSLLDSPIRHRGKMVGIICSEHQGVPREWTRDERAFASALADLFGR
AMSAKEILDYQHQLKAINADLEVQVEQRTQELETALSDLRSIQHHLVENEKMAALGSLVAGVAHEVNTPLGIAVTSVTHC
LDEVALLKTAFEQNELDEDKFLSFINTMQDGLGLIERNLSRAAELVHNFKRTAADQSVLERERFNLKTYIFQIFSSLRPL
MRKKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHGFPESFTGDKSITIRVQKQDSNICMQYQDNGVGMSDEVKLK
AFEPFFTTARKDGGTGLGMSIIYNLVTQKLHGTILLASSPDQGVKVEIQIPEK
>Mature_452_residues
TRMLDRILFDVSRSSIIDGGDLVEASQLIVTSVCQGLKITRAGIWLWSEDHQSMHCFYLLDNMHRQEALILTRQDYPHYF
SLLDNERAIVANHAQTDGATHEFVSAYLVPNRISSLLDSPIRHRGKMVGIICSEHQGVPREWTRDERAFASALADLFGRA
MSAKEILDYQHQLKAINADLEVQVEQRTQELETALSDLRSIQHHLVENEKMAALGSLVAGVAHEVNTPLGIAVTSVTHCL
DEVALLKTAFEQNELDEDKFLSFINTMQDGLGLIERNLSRAAELVHNFKRTAADQSVLERERFNLKTYIFQIFSSLRPLM
RKKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHGFPESFTGDKSITIRVQKQDSNICMQYQDNGVGMSDEVKLKA
FEPFFTTARKDGGTGLGMSIIYNLVTQKLHGTILLASSPDQGVKVEIQIPEK

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the kinB activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=299, Percent_Identity=23.7458193979933, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=292, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=23.5507246376812, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=303, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=24.7058823529412, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50994; Mature: 50863

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMLDRILFDVSRSSIIDGGDLVEASQLIVTSVCQGLKITRAGIWLWSEDHQSMHCFYL
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEEEEE
LDNMHRQEALILTRQDYPHYFSLLDNERAIVANHAQTDGATHEFVSAYLVPNRISSLLDS
EHHCCCCCEEEEEECCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCC
PIRHRGKMVGIICSEHQGVPREWTRDERAFASALADLFGRAMSAKEILDYQHQLKAINAD
HHHHCCCEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
LEVQVEQRTQELETALSDLRSIQHHLVENEKMAALGSLVAGVAHEVNTPLGIAVTSVTHC
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LDEVALLKTAFEQNELDEDKFLSFINTMQDGLGLIERNLSRAAELVHNFKRTAADQSVLE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERFNLKTYIFQIFSSLRPLMRKKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHG
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHCC
FPESFTGDKSITIRVQKQDSNICMQYQDNGVGMSDEVKLKAFEPFFTTARKDGGTGLGMS
CCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEEECHHHHHHCCCCCCCHHHH
IIYNLVTQKLHGTILLASSPDQGVKVEIQIPEK
HHHHHHHHHHCCEEEEECCCCCCEEEEEECCCC
>Mature Secondary Structure 
TRMLDRILFDVSRSSIIDGGDLVEASQLIVTSVCQGLKITRAGIWLWSEDHQSMHCFYL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEEEEE
LDNMHRQEALILTRQDYPHYFSLLDNERAIVANHAQTDGATHEFVSAYLVPNRISSLLDS
EHHCCCCCEEEEEECCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCC
PIRHRGKMVGIICSEHQGVPREWTRDERAFASALADLFGRAMSAKEILDYQHQLKAINAD
HHHHCCCEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
LEVQVEQRTQELETALSDLRSIQHHLVENEKMAALGSLVAGVAHEVNTPLGIAVTSVTHC
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LDEVALLKTAFEQNELDEDKFLSFINTMQDGLGLIERNLSRAAELVHNFKRTAADQSVLE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERFNLKTYIFQIFSSLRPLMRKKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHG
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHCC
FPESFTGDKSITIRVQKQDSNICMQYQDNGVGMSDEVKLKAFEPFFTTARKDGGTGLGMS
CCCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEEECHHHHHHCCCCCCCHHHH
IIYNLVTQKLHGTILLASSPDQGVKVEIQIPEK
HHHHHHHHHHCCEEEEECCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8497199; 9274030; 9384377 [H]