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The map label for this gene is (rmlA1 [H]

Identifier: 117919828

GI number: 117919828

Start: 1595572

End: 1596432

Strand: Direct

Name: (rmlA1 [H]

Synonym: Shewana3_1380

Alternate gene names: 117919828

Gene position: 1595572-1596432 (Clockwise)

Preceding gene: 117919827

Following gene: 117919829

Centisome position: 32.09

GC content: 40.07

Gene sequence:

>861_bases
ATGAAAGGAATTATTTTAGCTGGCGGTTCTGGTACACGGTTGTATCCACTTACTCGAGGTGTGTCAAAACAACTGCTCCC
AATTTATGATAAACCAATGATTTACTATCCTTTATCTACACTAATGCTAGCCGGAATTCGAGATGTATTGATTATTACCA
CCCCAGAAGATAACGATAGCTTTAAACGATTATTAGGTAATGGGTCAGATTTTGGCATCAACTTGAGTTATGCCGTTCAA
CCCTTTCCTGACGGTTTAGCTCAAGCTTTTATCATCGGTGAAGAATTTATCGGTAACTCAAATGTGTGTTTGGTGCTTGG
TGATAATATTTTTTATGGTCAATCTTTTTCAAAGACACTTAAAAATGCTGCGAATCGCCAAACTGGGGCTACTGTTTTCG
GCTATCAAGTAAAAGATCCTGAGCGTTTTGGGGTTGTGGAATTCGATGCTGAGATGAAGGCGGTTTCTATTGAGGAAAAA
CCACTCAAACCTAAATCATCTTATGCAGTAACAGGACTCTATTTTTACGACAATAAAGTGGTGGAACTGGCGAAACAGGT
TAAGCCTTCACATCGCGGTGAGCTTGAGATCACTACTCTTAATGAAATGTATCTCAAGGCCGGTGAGTTAAATGTTGAGC
TTCTTGGTCGTGGCTTTGCTTGGTTAGACACTGGAACTCATGAGAGTCTGCATGAAGCATCCTCTTTTGTGCAAACCATT
GAGCACGTTCAGGGCTTAAAAGTAGCTTGTTTAGAAGAAATTGCCTATCGAAATGGCTGGTTAACTGCAGATCAACTTAA
AGAACTCGCGAAACCCATGCTTAAAAATGACTATGGTCAGTATTTAGCACACTTAAAGTAG

Upstream 100 bases:

>100_bases
ACCTATCAGCGTGAGCGTTTAGGTATTTAATCACTTTAACAACTTTATTTTAAAGTCCTAGTTTTCACCTAGGGCCTATT
TACCTAGGAACTTGATTTAA

Downstream 100 bases:

>100_bases
TCTTGATTGCTTTGTGTTGAATGTTGAGTTTTCTGTCTCAGCATTCAGCATTCAGCATTCAGCATTTACTTACACCTCAC
AATTAACAATTCAACACTAT

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKGIILAGGSGTRLYPLTRGVSKQLLPIYDKPMIYYPLSTLMLAGIRDVLIITTPEDNDSFKRLLGNGSDFGINLSYAVQ
PFPDGLAQAFIIGEEFIGNSNVCLVLGDNIFYGQSFSKTLKNAANRQTGATVFGYQVKDPERFGVVEFDAEMKAVSIEEK
PLKPKSSYAVTGLYFYDNKVVELAKQVKPSHRGELEITTLNEMYLKAGELNVELLGRGFAWLDTGTHESLHEASSFVQTI
EHVQGLKVACLEEIAYRNGWLTADQLKELAKPMLKNDYGQYLAHLK

Sequences:

>Translated_286_residues
MKGIILAGGSGTRLYPLTRGVSKQLLPIYDKPMIYYPLSTLMLAGIRDVLIITTPEDNDSFKRLLGNGSDFGINLSYAVQ
PFPDGLAQAFIIGEEFIGNSNVCLVLGDNIFYGQSFSKTLKNAANRQTGATVFGYQVKDPERFGVVEFDAEMKAVSIEEK
PLKPKSSYAVTGLYFYDNKVVELAKQVKPSHRGELEITTLNEMYLKAGELNVELLGRGFAWLDTGTHESLHEASSFVQTI
EHVQGLKVACLEEIAYRNGWLTADQLKELAKPMLKNDYGQYLAHLK
>Mature_286_residues
MKGIILAGGSGTRLYPLTRGVSKQLLPIYDKPMIYYPLSTLMLAGIRDVLIITTPEDNDSFKRLLGNGSDFGINLSYAVQ
PFPDGLAQAFIIGEEFIGNSNVCLVLGDNIFYGQSFSKTLKNAANRQTGATVFGYQVKDPERFGVVEFDAEMKAVSIEEK
PLKPKSSYAVTGLYFYDNKVVELAKQVKPSHRGELEITTLNEMYLKAGELNVELLGRGFAWLDTGTHESLHEASSFVQTI
EHVQGLKVACLEEIAYRNGWLTADQLKELAKPMLKNDYGQYLAHLK

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790224, Length=285, Percent_Identity=73.3333333333333, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1788351, Length=281, Percent_Identity=68.6832740213523, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI133931050, Length=226, Percent_Identity=26.1061946902655, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=228, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355443, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644084, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 31744; Mature: 31744

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIILAGGSGTRLYPLTRGVSKQLLPIYDKPMIYYPLSTLMLAGIRDVLIITTPEDNDS
CCCEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEEEECCCCCHH
FKRLLGNGSDFGINLSYAVQPFPDGLAQAFIIGEEFIGNSNVCLVLGDNIFYGQSFSKTL
HHHHHCCCCCCEEEEEEEECCCCCHHHHHHEEHHHHCCCCCEEEEECCCEEECCHHHHHH
KNAANRQTGATVFGYQVKDPERFGVVEFDAEMKAVSIEEKPLKPKSSYAVTGLYFYDNKV
HHHCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEEECCHH
VELAKQVKPSHRGELEITTLNEMYLKAGELNVELLGRGFAWLDTGTHESLHEASSFVQTI
HHHHHHCCCCCCCEEEEEEHHHHHHCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHH
EHVQGLKVACLEEIAYRNGWLTADQLKELAKPMLKNDYGQYLAHLK
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MKGIILAGGSGTRLYPLTRGVSKQLLPIYDKPMIYYPLSTLMLAGIRDVLIITTPEDNDS
CCCEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEEEECCCCCHH
FKRLLGNGSDFGINLSYAVQPFPDGLAQAFIIGEEFIGNSNVCLVLGDNIFYGQSFSKTL
HHHHHCCCCCCEEEEEEEECCCCCHHHHHHEEHHHHCCCCCEEEEECCCEEECCHHHHHH
KNAANRQTGATVFGYQVKDPERFGVVEFDAEMKAVSIEEKPLKPKSSYAVTGLYFYDNKV
HHHCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEEECCHH
VELAKQVKPSHRGELEITTLNEMYLKAGELNVELLGRGFAWLDTGTHESLHEASSFVQTI
HHHHHHCCCCCCCEEEEEEHHHHHHCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHH
EHVQGLKVACLEEIAYRNGWLTADQLKELAKPMLKNDYGQYLAHLK
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]