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The map label for this gene is corC [H]

Identifier: 117919454

GI number: 117919454

Start: 1175816

End: 1176691

Strand: Reverse

Name: corC [H]

Synonym: Shewana3_1005

Alternate gene names: 117919454

Gene position: 1176691-1175816 (Counterclockwise)

Preceding gene: 117919455

Following gene: 117919453

Centisome position: 23.67

GC content: 46.58

Gene sequence:

>876_bases
ATGAGTGACGATATCCCCCCGAGTACGAGCGCCCAAAAGAAAGGCTGGTTTGACAGAGTAAGTCAGTTATTTCAGGGCGA
ACCTCAAAATCGCGAAGACTTAGTCGATGTGATTGATGGCGCAGAGCAGCGCGAGTTAATCACCGAAGACACCCGCGAAA
TGATCAAAGGTGTATTAGAAGTTTCTGATATGCGTGTTCGGGATATTATGATCCCACGAGCTCAAATTGTCGCGATTCAA
ATCGACAATACTGTCGAAGAATTGCTCGCAACTGTTATCGGTTCAGGCCATTCTCGCTTCCCTGTGGTTAACGAAGATAA
GGACCATATCGAAGGCATTTTACTGGCTAAAGATTTGATCCCCTATGGTTTCTCAAACAGTGAAGAACCCTTCTCCCTTG
AGCGCGTGATCCGCCCCGCCGTCGTTGTGCCAGAGAGCAAACGCGTCGACGTATTACTCAAAGAATTCCGCTCCCAGCGT
TACCATATGGCGATTGTCGTCGACGAATACGGCGGAGTATCGGGTCTAGTGACCATTGAAGATATTCTCGAAGAAATCGT
CGGTGAGATTGAAGACGAATTCGACCACGATAGCCCTGAAGATACTGAGATCCGCAAAGTCGGTAACACTGTCTACATGG
TAAAAGCGTTGACGCCTATCGAGGATTTTAACGAAGAATTCAATACTCACTTCAGCGATGAAGAGTTTGATACCGTCGGT
GGTTTAGTGTCCCATGCCTTTGGTCATCTACCAGAGCGTAATGAGAGCATTATGATCGAAGGAATTGAATTTAAAGTCAT
CAATGCCGATACCAGACGCTTAATCCAACTCAGAGTTAAACTCCCCGATCCCAATGTCGGTGAAGACGTAGAATAA

Upstream 100 bases:

>100_bases
GTCGTTAGAGACTCAACTCATTGAAAGCTTAGGTTTTACTGACCCATATAAGGAACAATAATTAACCACGGTGCACAGCA
TCAAGGTTAATGAGAAAACT

Downstream 100 bases:

>100_bases
CCCTCTACGTAAGAATAACGCTCAGTGTAAGAAGAATTATCCGTGCTAACTAACATTCGGGCTTTTGCCCAACAAAAGTC
CCGACTGAGCGTGTTACGGC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSDDIPPSTSAQKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRELITEDTREMIKGVLEVSDMRVRDIMIPRAQIVAIQ
IDNTVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLIPYGFSNSEEPFSLERVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSPEDTEIRKVGNTVYMVKALTPIEDFNEEFNTHFSDEEFDTVG
GLVSHAFGHLPERNESIMIEGIEFKVINADTRRLIQLRVKLPDPNVGEDVE

Sequences:

>Translated_291_residues
MSDDIPPSTSAQKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRELITEDTREMIKGVLEVSDMRVRDIMIPRAQIVAIQ
IDNTVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLIPYGFSNSEEPFSLERVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSPEDTEIRKVGNTVYMVKALTPIEDFNEEFNTHFSDEEFDTVG
GLVSHAFGHLPERNESIMIEGIEFKVINADTRRLIQLRVKLPDPNVGEDVE
>Mature_290_residues
SDDIPPSTSAQKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRELITEDTREMIKGVLEVSDMRVRDIMIPRAQIVAIQI
DNTVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLIPYGFSNSEEPFSLERVIRPAVVVPESKRVDVLLKEFRSQRY
HMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSPEDTEIRKVGNTVYMVKALTPIEDFNEEFNTHFSDEEFDTVGG
LVSHAFGHLPERNESIMIEGIEFKVINADTRRLIQLRVKLPDPNVGEDVE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=220, Percent_Identity=33.1818181818182, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI94681046, Length=180, Percent_Identity=31.1111111111111, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40068053, Length=184, Percent_Identity=27.7173913043478, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40068055, Length=184, Percent_Identity=27.7173913043478, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786879, Length=286, Percent_Identity=60.4895104895105, Blast_Score=324, Evalue=4e-90,
Organism=Escherichia coli, GI145693175, Length=241, Percent_Identity=26.1410788381743, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790664, Length=250, Percent_Identity=24.4, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788119, Length=246, Percent_Identity=32.9268292682927, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082033, Length=231, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32945; Mature: 32814

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDIPPSTSAQKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRELITEDTREMIKGVLE
CCCCCCCCCCCHHCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VSDMRVRDIMIPRAQIVAIQIDNTVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLI
HHCCHHHHEECCCEEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
PYGFSNSEEPFSLERVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
CCCCCCCCCCHHHHHHHCCCEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGEIEDEFDHDSPEDTEIRKVGNTVYMVKALTPIEDFNEEFNTHFSDEEFDTVG
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHH
GLVSHAFGHLPERNESIMIEGIEFKVINADTRRLIQLRVKLPDPNVGEDVE
HHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SDDIPPSTSAQKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRELITEDTREMIKGVLE
CCCCCCCCCCHHCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VSDMRVRDIMIPRAQIVAIQIDNTVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLI
HHCCHHHHEECCCEEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
PYGFSNSEEPFSLERVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
CCCCCCCCCCHHHHHHHCCCEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGEIEDEFDHDSPEDTEIRKVGNTVYMVKALTPIEDFNEEFNTHFSDEEFDTVG
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHH
GLVSHAFGHLPERNESIMIEGIEFKVINADTRRLIQLRVKLPDPNVGEDVE
HHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]