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The map label for this gene is hlyB [H]

Identifier: 117919216

GI number: 117919216

Start: 885489

End: 887351

Strand: Direct

Name: hlyB [H]

Synonym: Shewana3_0764

Alternate gene names: 117919216

Gene position: 885489-887351 (Clockwise)

Preceding gene: 117919212

Following gene: 117919220

Centisome position: 17.81

GC content: 47.77

Gene sequence:

>1863_bases
ATGTTAATCCGCTCAAAGTTGTTACTCAGTGCCGCTGTATCCGTTACGGCCTTGATTGCCATGTTTGGATTGCAGCTTCA
TTCAAATTCGGTTGAGTCGGAACTCTCCCACGCAGCACAAAGCGTTCTCGAATTGGAGCGAGATGTATTGCTACTGCGTA
AAAATGAAAAGGATTTTTTTGGTCGTAAAGATATGCAGTATGTTCAACTGCATGGTGAGGTACATGCCAAGATTGATGAG
TTAGTCCCGAATCTTGAGAGTATTTTTAAAAAATACAAGGTTTCCACTGCGCCACTCGAAAGTTTTGACCGTAACCTTAA
TCAGTACCAAGTCGCCTTCAATGAAGTCGTACAACTGCAGCAAGAAATTGGTTTAACGCCTAAAACGGGTCTCTACGGCA
CCTTAAGAACGGCAGTGCACAATGTTGAGTCCATGCTGAAGGAATACGACCAGTTATCCCTCGAAGTTGCCATGTTGCAG
CTAAGACGCAATGAGAAAGACTTTATGCTGCGCCGCGAGATGAGCTATGTCGAGACCTTCGACTCGAATATTGCTCAGTT
CAACACAAGTCTGCGTGCATCCAGCTTAGATTTTGATACACAAAATAAAATTGCGGCCCTAATTGAGCAATATCAAAAGG
ATTTTAAGAGCTTAGTCAATAAAGAGCAGCAACTGGGGCTCAGTGAAAAAGATGGCACTATGGCGAAATTGATCGCCGCA
AACAAGTTAACCGAGGCCAGTGCCGACGAGCTGCATAATCTTGCGTTAAAGGCGATTGATGATACCGAAAGCAGCAGTGT
GAATATCGGGATTTTGGTCTTCGTGATTATCGCCCTGATCCTTGCAGTGATTACTTACCTTATTATCCGCAGCATTATCA
CCCCGGTGGAACGTATAACGCAGGTGATTTCACGTATCGAAGTCAGCAAAGACTTAACCCTCAGATGCGATGCCTCGACT
CAGGATGAGCTGGGTGAAATTGCGCAGCATTTCAATAGCATGGTGGGGAGCTTTCAGCAGCTTATCGAGCAGGTTATTGA
CTCAGTCGCCACGATTAACACGTCCTGTAAGAGTGTGTCAGAGAATGCAATGCTCGCCTCCGAAGGCGTTGCTCAGCAGC
TTAATGAAACCGATATGGTGGCGACGGCGATTACCGAAATGGGCGCGACCATTGATGAAATTGCTAAAACGACCGAGCTT
GCGGCCCTCAAAGCGGGTAAAACCCATGATAACGCTCAATTAGGGCAAACTGAGGTGGAGCAAACCATCCTCAAGATCAG
ACAATTGTCTGAACAAATTAACAGCAGCGCCTCAGTGGTGGATGAGCTCGAGCGTGATAGTGAAACCATTGGTAGCGTGC
TCGATGTGATCCGTGGCATTGCGGAACAAACCAATTTACTGGCACTCAATGCGGCGATTGAAGCGGCCCGCGCGGGTGAA
CAAGGCCGTGGTTTTGCCGTGGTTGCCGACGAAGTACGTAGTCTGGCGATGCGAACTCAGACATCAACTCAGGAGATTGC
CAATATTATTCAAACCCTGCAAAGTCGAACCCGCGCAATAGTGCAATTAATGGATGCGAGCCAAAAGCAAGGCGCCGAGA
GTGCCGAGCAGGCTGCGGCGGCGGGAGAATTGCTGAAGCTTATCAATACCGATGTGCATAATATTATGGATATGAGCACT
CAGATTGCTGCAGCGATTGAAGAGCAGAGCATGGTTGCCGCCGAAGTGAATAAGAACGTGGTCGTTATCCGTGATATTGC
TGAGGATTCTTCTCGGGCTGCCGATGCCAATGCATCGGCTTCGGATGAACTTAAATCCCGCGCCGAGTATCTAGTCAGTG
CCGTGAGCCACTTTAAGATCTAG

Upstream 100 bases:

>100_bases
AATAAATAGAAGATAAACTTTGTATATCAGGGATATTTTGCTGTTAAAGGCCTAACTCCCAGCTATCTTTTTAAGAGAAG
TTATTTATTAGGGGCTTTTT

Downstream 100 bases:

>100_bases
TCGCACTTTTGTCTGTCAGAAACGCACCTTAGGGGGCGTTTTTTTATGGCGAAGCGCTGTTGAGGTTTATTTGAATATGA
TGGCGCACGAGCTATTAATA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MLIRSKLLLSAAVSVTALIAMFGLQLHSNSVESELSHAAQSVLELERDVLLLRKNEKDFFGRKDMQYVQLHGEVHAKIDE
LVPNLESIFKKYKVSTAPLESFDRNLNQYQVAFNEVVQLQQEIGLTPKTGLYGTLRTAVHNVESMLKEYDQLSLEVAMLQ
LRRNEKDFMLRREMSYVETFDSNIAQFNTSLRASSLDFDTQNKIAALIEQYQKDFKSLVNKEQQLGLSEKDGTMAKLIAA
NKLTEASADELHNLALKAIDDTESSSVNIGILVFVIIALILAVITYLIIRSIITPVERITQVISRIEVSKDLTLRCDAST
QDELGEIAQHFNSMVGSFQQLIEQVIDSVATINTSCKSVSENAMLASEGVAQQLNETDMVATAITEMGATIDEIAKTTEL
AALKAGKTHDNAQLGQTEVEQTILKIRQLSEQINSSASVVDELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQTSTQEIANIIQTLQSRTRAIVQLMDASQKQGAESAEQAAAAGELLKLINTDVHNIMDMST
QIAAAIEEQSMVAAEVNKNVVVIRDIAEDSSRAADANASASDELKSRAEYLVSAVSHFKI

Sequences:

>Translated_620_residues
MLIRSKLLLSAAVSVTALIAMFGLQLHSNSVESELSHAAQSVLELERDVLLLRKNEKDFFGRKDMQYVQLHGEVHAKIDE
LVPNLESIFKKYKVSTAPLESFDRNLNQYQVAFNEVVQLQQEIGLTPKTGLYGTLRTAVHNVESMLKEYDQLSLEVAMLQ
LRRNEKDFMLRREMSYVETFDSNIAQFNTSLRASSLDFDTQNKIAALIEQYQKDFKSLVNKEQQLGLSEKDGTMAKLIAA
NKLTEASADELHNLALKAIDDTESSSVNIGILVFVIIALILAVITYLIIRSIITPVERITQVISRIEVSKDLTLRCDAST
QDELGEIAQHFNSMVGSFQQLIEQVIDSVATINTSCKSVSENAMLASEGVAQQLNETDMVATAITEMGATIDEIAKTTEL
AALKAGKTHDNAQLGQTEVEQTILKIRQLSEQINSSASVVDELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQTSTQEIANIIQTLQSRTRAIVQLMDASQKQGAESAEQAAAAGELLKLINTDVHNIMDMST
QIAAAIEEQSMVAAEVNKNVVVIRDIAEDSSRAADANASASDELKSRAEYLVSAVSHFKI
>Mature_620_residues
MLIRSKLLLSAAVSVTALIAMFGLQLHSNSVESELSHAAQSVLELERDVLLLRKNEKDFFGRKDMQYVQLHGEVHAKIDE
LVPNLESIFKKYKVSTAPLESFDRNLNQYQVAFNEVVQLQQEIGLTPKTGLYGTLRTAVHNVESMLKEYDQLSLEVAMLQ
LRRNEKDFMLRREMSYVETFDSNIAQFNTSLRASSLDFDTQNKIAALIEQYQKDFKSLVNKEQQLGLSEKDGTMAKLIAA
NKLTEASADELHNLALKAIDDTESSSVNIGILVFVIIALILAVITYLIIRSIITPVERITQVISRIEVSKDLTLRCDAST
QDELGEIAQHFNSMVGSFQQLIEQVIDSVATINTSCKSVSENAMLASEGVAQQLNETDMVATAITEMGATIDEIAKTTEL
AALKAGKTHDNAQLGQTEVEQTILKIRQLSEQINSSASVVDELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQTSTQEIANIIQTLQSRTRAIVQLMDASQKQGAESAEQAAAAGELLKLINTDVHNIMDMST
QIAAAIEEQSMVAAEVNKNVVVIRDIAEDSSRAADANASASDELKSRAEYLVSAVSHFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=346, Percent_Identity=28.3236994219653, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=31.3588850174216, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=252, Percent_Identity=30.5555555555556, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=346, Percent_Identity=25.7225433526012, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68066; Mature: 68066

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRSKLLLSAAVSVTALIAMFGLQLHSNSVESELSHAAQSVLELERDVLLLRKNEKDFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
GRKDMQYVQLHGEVHAKIDELVPNLESIFKKYKVSTAPLESFDRNLNQYQVAFNEVVQLQ
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHH
QEIGLTPKTGLYGTLRTAVHNVESMLKEYDQLSLEVAMLQLRRNEKDFMLRREMSYVETF
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DSNIAQFNTSLRASSLDFDTQNKIAALIEQYQKDFKSLVNKEQQLGLSEKDGTMAKLIAA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHH
NKLTEASADELHNLALKAIDDTESSSVNIGILVFVIIALILAVITYLIIRSIITPVERIT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVISRIEVSKDLTLRCDASTQDELGEIAQHFNSMVGSFQQLIEQVIDSVATINTSCKSVS
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAMLASEGVAQQLNETDMVATAITEMGATIDEIAKTTELAALKAGKTHDNAQLGQTEVE
HCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
QTILKIRQLSEQINSSASVVDELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQTSTQEIANIIQTLQSRTRAIVQLMDASQKQGAESAEQAAA
CCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGELLKLINTDVHNIMDMSTQIAAAIEEQSMVAAEVNKNVVVIRDIAEDSSRAADANASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
SDELKSRAEYLVSAVSHFKI
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIRSKLLLSAAVSVTALIAMFGLQLHSNSVESELSHAAQSVLELERDVLLLRKNEKDFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
GRKDMQYVQLHGEVHAKIDELVPNLESIFKKYKVSTAPLESFDRNLNQYQVAFNEVVQLQ
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHH
QEIGLTPKTGLYGTLRTAVHNVESMLKEYDQLSLEVAMLQLRRNEKDFMLRREMSYVETF
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DSNIAQFNTSLRASSLDFDTQNKIAALIEQYQKDFKSLVNKEQQLGLSEKDGTMAKLIAA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHH
NKLTEASADELHNLALKAIDDTESSSVNIGILVFVIIALILAVITYLIIRSIITPVERIT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVISRIEVSKDLTLRCDASTQDELGEIAQHFNSMVGSFQQLIEQVIDSVATINTSCKSVS
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAMLASEGVAQQLNETDMVATAITEMGATIDEIAKTTELAALKAGKTHDNAQLGQTEVE
HCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
QTILKIRQLSEQINSSASVVDELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQTSTQEIANIIQTLQSRTRAIVQLMDASQKQGAESAEQAAA
CCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGELLKLINTDVHNIMDMSTQIAAAIEEQSMVAAEVNKNVVVIRDIAEDSSRAADANASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
SDELKSRAEYLVSAVSHFKI
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]