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The map label for this gene is hemA [H]

Identifier: 117919220

GI number: 117919220

Start: 890351

End: 891601

Strand: Direct

Name: hemA [H]

Synonym: Shewana3_0768

Alternate gene names: 117919220

Gene position: 890351-891601 (Clockwise)

Preceding gene: 117919216

Following gene: 117919221

Centisome position: 17.91

GC content: 49.0

Gene sequence:

>1251_bases
ATGAGCCTTGTAGCAATCGGTATTAACCATAAAACAGCCACGGTAGACCTGCGTGAGAAAGTTGCCTTCTCTCCGGACAA
AATTCATGATGCCATGAAGAGTCTGGCCAGTCGTACACGCTCGGGTGAAGCCGTTATCGTCTCGACCTGTAATCGCACTG
AATTGTATTGTAACAATGGCGATGAGGCCGACATCATTGAGTGGCTTGAAGAATATCATGGCCTAGATCATCAAGATGTA
GCGCCGTGCCTCTACAATTACCACGGTCAAGCGGCGGTAAGGCATTTAATGCGCGTGGCCTCGGGTCTTGACTCGCTGAT
TTTGGGTGAGCCGCAAATTCTGGGGCAGGTTAAGCAGGCTTTTGTCAAAGCCAAAGAAGCGGGTACCGTTGCGCTAACCA
TCGATCGCTTATTCCAAAATACCTTCTCCGTGGCGAAAAAAGTGCGTACCGAAACCGAAATCGGTGCCGCAGCTGTCTCG
GTGGCCTTTGCCGCCGTGAGCATGGCAAAACATATCTTCTCTTCGCTGTCGACCACTAAGGTGCTGTTAATTGGTGCCGG
TGAAACCATTGAGCTGGTGGCTAAACATCTTAAGGATAACGGTGTTGCTTCTATGGTCGTGGCAAACCGTACTCTGGAAC
GTGCTCAAAGCATGTGTGAAGAGTTTAATGCCACGGCAATTACGCTGGCACAGATACCAGATTTTCTCCCTAAAGCCGAT
ATCGTGATATCCTCTACCGCCAGCCCGCTACCAATCCTTGGTAAAGGCATGGTAGAAAAAGCGCTAAAGCAGCGTCGCCA
TCAACCTATGTTATTGGTTGATATAGCAGTTCCCCGGGATATTGAGCCGGAAGTCGCCGATTTGGACGATGCGTTTCTGT
ATACAGTGGACGACCTGCATAGCATTATTGAACAGAATAAGGCTTCCCGTAAGGAGGCCGCCGAGCAAGCTGAATTAATT
ACTGAAGAACAATCCTACCTCTTTATGGATTGGGTACGTTCTTTAGAGTCGGTCGACAGTATTCGCGAGTATCGCAGCCA
AAGCATGGCGATAAAGGATGAGTTAGTGGAACGCGCCCTGAATAAATTAGCGCAGGGGGGCGACACTGAGCAGGTATTGA
TTGAACTAGCCAATCGCCTGACAAATAGACTTATTCACGCACCAACCCAAGCCCTCACAGTGGCGAGTCGTCAGGGTGAT
TTGAATACCTTAGGTCAGTTAAGAACAGCGCTCGGATTAGATAAAAACTAA

Upstream 100 bases:

>100_bases
ACCTTTATTCGGTTTTGTTAAGCGTATTCTGTTTTTAGTTGGGCCAATTCAGTAGAATGCCCTTATTAAGAGAGACGCCA
AGAATCTAGAAAAGAGTCAG

Downstream 100 bases:

>100_bases
GGTTAGCGAGTTAAATGAAGGAATCCGTTATCCGCAAGCTGGAAGGCTTGCTCGAGCGCAATGAAGAAGTCTTAGCCTTG
CTTGGTGATGCGTCCGTTAT

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNGDEADIIEWLEEYHGLDHQDV
APCLYNYHGQAAVRHLMRVASGLDSLILGEPQILGQVKQAFVKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVS
VAFAAVSMAKHIFSSLSTTKVLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQSMCEEFNATAITLAQIPDFLPKAD
IVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLHSIIEQNKASRKEAAEQAELI
TEEQSYLFMDWVRSLESVDSIREYRSQSMAIKDELVERALNKLAQGGDTEQVLIELANRLTNRLIHAPTQALTVASRQGD
LNTLGQLRTALGLDKN

Sequences:

>Translated_416_residues
MSLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNGDEADIIEWLEEYHGLDHQDV
APCLYNYHGQAAVRHLMRVASGLDSLILGEPQILGQVKQAFVKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVS
VAFAAVSMAKHIFSSLSTTKVLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQSMCEEFNATAITLAQIPDFLPKAD
IVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLHSIIEQNKASRKEAAEQAELI
TEEQSYLFMDWVRSLESVDSIREYRSQSMAIKDELVERALNKLAQGGDTEQVLIELANRLTNRLIHAPTQALTVASRQGD
LNTLGQLRTALGLDKN
>Mature_415_residues
SLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNGDEADIIEWLEEYHGLDHQDVA
PCLYNYHGQAAVRHLMRVASGLDSLILGEPQILGQVKQAFVKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVSV
AFAAVSMAKHIFSSLSTTKVLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQSMCEEFNATAITLAQIPDFLPKADI
VISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLHSIIEQNKASRKEAAEQAELIT
EEQSYLFMDWVRSLESVDSIREYRSQSMAIKDELVERALNKLAQGGDTEQVLIELANRLTNRLIHAPTQALTVASRQGDL
NTLGQLRTALGLDKN

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=419, Percent_Identity=57.2792362768496, Blast_Score=460, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 45611; Mature: 45479

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNG
CCEEEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCC
DEADIIEWLEEYHGLDHQDVAPCLYNYHGQAAVRHLMRVASGLDSLILGEPQILGQVKQA
CCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHH
FVKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVSVAFAAVSMAKHIFSSLSTTK
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQSMCEEFNATAITLAQIPDFLPKAD
EEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCC
IVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLH
EEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHH
SIIEQNKASRKEAAEQAELITEEQSYLFMDWVRSLESVDSIREYRSQSMAIKDELVERAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKLAQGGDTEQVLIELANRLTNRLIHAPTQALTVASRQGDLNTLGQLRTALGLDKN
HHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNG
CEEEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCC
DEADIIEWLEEYHGLDHQDVAPCLYNYHGQAAVRHLMRVASGLDSLILGEPQILGQVKQA
CCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHH
FVKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVSVAFAAVSMAKHIFSSLSTTK
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQSMCEEFNATAITLAQIPDFLPKAD
EEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCC
IVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLH
EEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHH
SIIEQNKASRKEAAEQAELITEEQSYLFMDWVRSLESVDSIREYRSQSMAIKDELVERAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKLAQGGDTEQVLIELANRLTNRLIHAPTQALTVASRQGDLNTLGQLRTALGLDKN
HHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA