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The map label for this gene is hflK [H]

Identifier: 117919052

GI number: 117919052

Start: 702512

End: 703657

Strand: Direct

Name: hflK [H]

Synonym: Shewana3_0599

Alternate gene names: 117919052

Gene position: 702512-703657 (Clockwise)

Preceding gene: 117919051

Following gene: 117919053

Centisome position: 14.13

GC content: 48.87

Gene sequence:

>1146_bases
ATGGCTTGGAACGAGCCCGGTAACAAGGGTAATGATCCTTGGGGAAATAAAGGTGGTAACGACAAAGGACCACCAGACCT
TGATGAGGTTTTTCGTAATCTTTCAAAACGCTTTGGCGGCAAAGGCAATGGCTCATCAGGCCAGAGCTTTAGTTCGTTCA
GCTTAATCATCATTCTTGCCATCGCTTTTGTTGTTTGGGGACTCTCGGGTTTTTACACCATTAAAGAAGCTGAGCGTGGT
GTTGCGCTGCGTTTTGGTCAGCACATTGGTGAGGTGGGACCTGGTCTGCATTGGAAGGCTACGTTTATAGACCAGATTTA
TCCCGTTGATGTGCAATCTGTTCGCTCCATTCCTGCTTCTGGCAGCATGTTGACCTCAGATGAAAACGTCGTGAAGGTCG
AGCTGGACGTACAGTATCGTATTCTTGATGCGTATTCTTATCTGTTCAGTGCCGTTGATGCGAATGCCAGCTTACGCGAA
GCCACAGACAGTGCGCTGCGTTATGTTATCGGCCACAACAAGATGGACGATATTCTGACCACGGGTCGTGATGCGATTCG
TCGCGATACTTGGAAAGAACTCGAGCGCATCATTGAGCCGTACAAATTAGGCTTAGCCATTGTTGACGTTAACTTTTTGC
CTGCGCGTCCACCTGAAGAAGTGAAAGATGCTTTCGACGATGCGATTGCGGCACAAGAAGACGAACAACGCTTTATCCGT
GAAGCCGAAGCTTATGCCCGTGAAGTTGAGCCTAAAGCGCGCGGTGAAGTTGAGCGTATGGCGCAACAAGCGAATGCCTA
TAAAGAGCGTGAAATTCTTGAAGCTCGCGGTAAAGTGGCTCGTTTCGAGTTACTGTTGCCTGAGTACCAAGCGGCACCTG
AAGTGACCCGCAAGCGTTTGTATCTCGATGCAATGCAACAGGTGATGACAGATACCAACAAGGTACTGATCGACGCGAAG
AACAATGGCAATTTAATGTATTTGCCTTTAGACAAGTTAATGAAAGAGAAGCCTGTGACTACGCCAGAGGTTGAGCATAA
GGCTCAGCAGAACGTCAATTCTTCATCTATGTCAACGACTCGCATTGGTGAGCCTTTGAGTGGACGCCCTTCTCGCGAGG
ACCGTGCTCGCCAAGGGAGGGAGTAA

Upstream 100 bases:

>100_bases
ACAGAGTCAGGGTGAGTTAGAAACCTTTATCTTCGATCCGTCGACAGAAAAGGCTGTTTGTTAATAATCTAATTTATTTC
ATCCACTTATGGAGTGCTAA

Downstream 100 bases:

>100_bases
TCCATGGGTAGATTAAGTATTGTTCTGATTGCCATCGTATTAGGCATAGGTCTGTCATCTGTGATGGTGGTTAACGAAGG
CGAACGTGCGATTGTGGCGC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSSGQSFSSFSLIIILAIAFVVWGLSGFYTIKEAERG
VALRFGQHIGEVGPGLHWKATFIDQIYPVDVQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLRE
ATDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERIIEPYKLGLAIVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIR
EAEAYAREVEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQAAPEVTRKRLYLDAMQQVMTDTNKVLIDAK
NNGNLMYLPLDKLMKEKPVTTPEVEHKAQQNVNSSSMSTTRIGEPLSGRPSREDRARQGRE

Sequences:

>Translated_381_residues
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSSGQSFSSFSLIIILAIAFVVWGLSGFYTIKEAERG
VALRFGQHIGEVGPGLHWKATFIDQIYPVDVQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLRE
ATDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERIIEPYKLGLAIVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIR
EAEAYAREVEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQAAPEVTRKRLYLDAMQQVMTDTNKVLIDAK
NNGNLMYLPLDKLMKEKPVTTPEVEHKAQQNVNSSSMSTTRIGEPLSGRPSREDRARQGRE
>Mature_380_residues
AWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSSGQSFSSFSLIIILAIAFVVWGLSGFYTIKEAERGV
ALRFGQHIGEVGPGLHWKATFIDQIYPVDVQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREA
TDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERIIEPYKLGLAIVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIRE
AEAYAREVEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQAAPEVTRKRLYLDAMQQVMTDTNKVLIDAKN
NGNLMYLPLDKLMKEKPVTTPEVEHKAQQNVNSSSMSTTRIGEPLSGRPSREDRARQGRE

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=361, Percent_Identity=54.5706371191136, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 42711; Mature: 42579

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSSGQSFSSFSLIIILA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IAFVVWGLSGFYTIKEAERGVALRFGQHIGEVGPGLHWKATFIDQIYPVDVQSVRSIPAS
HHHHHHCCCCCEEHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHCCCCC
GSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREATDSALRYVIGHNKMDDILT
CCEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
TGRDAIRRDTWKELERIIEPYKLGLAIVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIR
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHH
EAEAYAREVEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQAAPEVTRKRL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHH
YLDAMQQVMTDTNKVLIDAKNNGNLMYLPLDKLMKEKPVTTPEVEHKAQQNVNSSSMSTT
HHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHH
RIGEPLSGRPSREDRARQGRE
HCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
AWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSSGQSFSSFSLIIILA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IAFVVWGLSGFYTIKEAERGVALRFGQHIGEVGPGLHWKATFIDQIYPVDVQSVRSIPAS
HHHHHHCCCCCEEHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHCCCCC
GSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREATDSALRYVIGHNKMDDILT
CCEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
TGRDAIRRDTWKELERIIEPYKLGLAIVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIR
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHH
EAEAYAREVEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQAAPEVTRKRL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHH
YLDAMQQVMTDTNKVLIDAKNNGNLMYLPLDKLMKEKPVTTPEVEHKAQQNVNSSSMSTT
HHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHH
RIGEPLSGRPSREDRARQGRE
HCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]