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The map label for this gene is hflX [H]

Identifier: 117919051

GI number: 117919051

Start: 701168

End: 702475

Strand: Direct

Name: hflX [H]

Synonym: Shewana3_0598

Alternate gene names: 117919051

Gene position: 701168-702475 (Clockwise)

Preceding gene: 117919050

Following gene: 117919052

Centisome position: 14.1

GC content: 49.01

Gene sequence:

>1308_bases
TTGTTTGATCGTTATGAGGCGGGAGAAACAGCGGTTCTTGTCCATATCGACTTTTCCGATGAGGAACGCCGGGAAGACTT
AGTCGAGTTACAGCTATTAGTCGAGTCAGCTGGAGCACGCTCAGTCGGGGTCATTACTGGAAGTCGACGCTCACCAGACC
GTAAGTTTTTTATTGGTTCTGGTAAAGCCGAGGAGTTAGCTGCATTAGTGGCTGCGACCGAGGCGAATGTGGTTATTTTC
AATCACGCCTTGAGTCCTGCTCAAGAGCGAAACCTTGAACAGGTGTGTCAGTGCCGTGTATTGGACCGAACCACGCTGAT
CTTGGATATTTTCGCTCAACGTGCTCGGACCCATGAAGGTAAGTTACAGGTGGAGCTAGCGCAATTGCGCCACATGTCGA
CGCGTCTTGTGCGTGGTTGGACTCACCTTGAGCGCCAAAAAGGTGGTATCGGTTTACGCGGTCCGGGTGAAACCCAGCTA
GAAACCGATAGACGTTTGCTCAGGGGCCGTATTAAAAATATCAATAAACGCTTAGAGCGTGTTGATAAACAACGTGAGCA
GAGTCGCCGCGCCCGTAAGCGTAGTGACATGCCAACAGTCTCATTAGTGGGTTATACCAACGCGGGCAAGTCAACGCTGT
TTAATGCCTTAACCTCATCTGATGTTTATGCAGCCGACCAGCTATTTGCCACACTCGATCCCACATTGAGAAAGTTAGAT
CTGCCCGACGGTGCCGTGATTTTAGCGGACACTGTAGGTTTTATTCGCCATTTACCACACGATCTGGTTGCCGCGTTCAA
GGCAACACTGCAGGAAACGCGTCAAGCGGATTTATTGCTGCATATCGTTGATTGTGCTGATGAAAACATGGCGGATAACT
TCGAGCAGGTGCAAAACGTGCTCGAAGATATCGATGCAGCCGAAGTGATGCAGTTGGTCGTTTGTAATAAAATCGACCTG
CTTGAGGATGTCACGCCGCGCATCGAATACGATGAACACGGTAAGCCCGTGCGCGTCTGGCTTTCGGCACAAAAACGTTT
GGGATTTGATCTGCTCCTGAAGGCAATCACCGAGTTGATTGGTGAAGTCATTCATGAGTTTACACTTAAGATTCCGGCTA
CTGCTGGACATTATCTTGGCCAGTTTTATCGACTGGATGCGATACAGCAGAAAGAGTACGACGATCTGGGGAACTGTATT
TTGTCTGTTCGTTTATCGGATGCCGATTGGCGCCGATTAGCTAAACAGAGTCAGGGTGAGTTAGAAACCTTTATCTTCGA
TCCGTCGACAGAAAAGGCTGTTTGTTAA

Upstream 100 bases:

>100_bases
GTCCATTTAACGTTGCTGGCCATCAAAATGCCCAGGGCGGTTATGGCGCGCAAGATGATATGCCAAGTGGCGAATAAGTT
TTAATTGAGGAGTTTGCTTC

Downstream 100 bases:

>100_bases
TAATCTAATTTATTTCATCCACTTATGGAGTGCTAAATGGCTTGGAACGAGCCCGGTAACAAGGGTAATGATCCTTGGGG
AAATAAAGGTGGTAACGACA

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGSGKAEELAALVAATEANVVIF
NHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINKRLERVDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNVLEDIDAAEVMQLVVCNKIDL
LEDVTPRIEYDEHGKPVRVWLSAQKRLGFDLLLKAITELIGEVIHEFTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLSDADWRRLAKQSQGELETFIFDPSTEKAVC

Sequences:

>Translated_435_residues
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGSGKAEELAALVAATEANVVIF
NHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINKRLERVDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNVLEDIDAAEVMQLVVCNKIDL
LEDVTPRIEYDEHGKPVRVWLSAQKRLGFDLLLKAITELIGEVIHEFTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLSDADWRRLAKQSQGELETFIFDPSTEKAVC
>Mature_435_residues
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGSGKAEELAALVAATEANVVIF
NHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINKRLERVDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNVLEDIDAAEVMQLVVCNKIDL
LEDVTPRIEYDEHGKPVRVWLSAQKRLGFDLLLKAITELIGEVIHEFTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLSDADWRRLAKQSQGELETFIFDPSTEKAVC

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=196, Percent_Identity=37.2448979591837, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310133118, Length=198, Percent_Identity=36.8686868686869, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310124269, Length=178, Percent_Identity=38.2022471910112, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124267, Length=178, Percent_Identity=38.2022471910112, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124171, Length=178, Percent_Identity=38.2022471910112, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124169, Length=178, Percent_Identity=38.2022471910112, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=64.5539906103286, Blast_Score=554, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17561038, Length=274, Percent_Identity=31.7518248175182, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24650079, Length=363, Percent_Identity=30.8539944903581, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49067; Mature: 49067

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGS
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECC
GKAEELAALVAATEANVVIFNHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEG
CCHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIKNINKRLER
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHCC
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNV
CCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHHH
LEDIDAAEVMQLVVCNKIDLLEDVTPRIEYDEHGKPVRVWLSAQKRLGFDLLLKAITELI
HHHCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHH
GEVIHEFTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCILSVRLSDADWRRLAKQSQGE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCC
LETFIFDPSTEKAVC
EEEEEECCCCCCCCC
>Mature Secondary Structure
MFDRYEAGETAVLVHIDFSDEERREDLVELQLLVESAGARSVGVITGSRRSPDRKFFIGS
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECC
GKAEELAALVAATEANVVIFNHALSPAQERNLEQVCQCRVLDRTTLILDIFAQRARTHEG
CCHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIKNINKRLER
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQREQSRRARKRSDMPTVSLVGYTNAGKSTLFNALTSSDVYAADQLFATLDPTLRKLD
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHCC
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHIVDCADENMADNFEQVQNV
CCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHHH
LEDIDAAEVMQLVVCNKIDLLEDVTPRIEYDEHGKPVRVWLSAQKRLGFDLLLKAITELI
HHHCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHH
GEVIHEFTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCILSVRLSDADWRRLAKQSQGE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCC
LETFIFDPSTEKAVC
EEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]