Click here to switch to the map view.

The map label for this gene is bsaA [H]

Identifier: 116872384

GI number: 116872384

Start: 989637

End: 990113

Strand: Direct

Name: bsaA [H]

Synonym: lwe0966

Alternate gene names: 116872384

Gene position: 989637-990113 (Clockwise)

Preceding gene: 116872383

Following gene: 116872385

Centisome position: 35.17

GC content: 33.33

Gene sequence:

>477_bases
ATGAATGTCCATGATTTTTCTGAAAAAGCAATGAATGGTAAAGAAATATCCTTAAGTGATTATAAAGGTAAAGTTTTATT
AATCGTTAATACTGCGAGTAAATGTGGCTTAACACCCCAACTAGAAGGTCTTGAGGCAATGTATAAAAAACTCGGCGGGG
CTAACTTTGAAATTCTTGGTTTTCCTTGTAACCAGTTTTTACGTCAAGATCCTGGTAGTGATGAAGAAATCTTAGAATTT
TGCCAAATGAATTATGGTGTAACTTTCCAAATGTTTTCTAAAATTAAAGTAAAAGGTAAAGATGCTAGTCCGCTATACAA
ATACTTAACTGAACAAACGGGCGGCAAAAAAGTAGAATGGAACTTTGCGAAATTCTTGATTGATGAAAATGGGGAAGTTG
TTGAACGTTTCTCTTCAAAAATGAAACCAGAAGATTTTGAGGATAAAGTGGAAGCACTTGTTGCAAATGTAAAATAA

Upstream 100 bases:

>100_bases
TCATGCTTATGAGCGTACACATCGAGATTCACTTTATCATACAGAAAAATTAGTTTATGCTTATTTATTTTCAAATATAA
TAAAATAGGAGGAATTCCAT

Downstream 100 bases:

>100_bases
ATATTAAAACTCGGTAATGAAAATGAATCATTACCGAGTTTTTTTGCATCTTAAGGAGGATAAAATGCAAGTTACCAAAA
TAAGCTTGTAGTTTCACTTA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNVHDFSEKAMNGKEISLSDYKGKVLLIVNTASKCGLTPQLEGLEAMYKKLGGANFEILGFPCNQFLRQDPGSDEEILEF
CQMNYGVTFQMFSKIKVKGKDASPLYKYLTEQTGGKKVEWNFAKFLIDENGEVVERFSSKMKPEDFEDKVEALVANVK

Sequences:

>Translated_158_residues
MNVHDFSEKAMNGKEISLSDYKGKVLLIVNTASKCGLTPQLEGLEAMYKKLGGANFEILGFPCNQFLRQDPGSDEEILEF
CQMNYGVTFQMFSKIKVKGKDASPLYKYLTEQTGGKKVEWNFAKFLIDENGEVVERFSSKMKPEDFEDKVEALVANVK
>Mature_158_residues
MNVHDFSEKAMNGKEISLSDYKGKVLLIVNTASKCGLTPQLEGLEAMYKKLGGANFEILGFPCNQFLRQDPGSDEEILEF
CQMNYGVTFQMFSKIKVKGKDASPLYKYLTEQTGGKKVEWNFAKFLIDENGEVVERFSSKMKPEDFEDKVEALVANVK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=154, Percent_Identity=42.8571428571429, Blast_Score=133, Evalue=6e-32,
Organism=Homo sapiens, GI90903240, Length=151, Percent_Identity=45.6953642384106, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI75709200, Length=151, Percent_Identity=45.6953642384106, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI192455698, Length=155, Percent_Identity=38.7096774193548, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI90903238, Length=133, Percent_Identity=45.1127819548872, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=31.6939890710383, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI4557629, Length=163, Percent_Identity=33.1288343558282, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI6006001, Length=163, Percent_Identity=31.2883435582822, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=27.4725274725275, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI33186887, Length=160, Percent_Identity=28.75, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1788003, Length=160, Percent_Identity=46.875, Blast_Score=141, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=44.375, Blast_Score=129, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=41.1392405063291, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=37.1069182389937, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI193210707, Length=160, Percent_Identity=33.125, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17550320, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193209493, Length=161, Percent_Identity=29.8136645962733, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71993573, Length=98, Percent_Identity=34.6938775510204, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=156, Percent_Identity=51.2820512820513, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322228, Length=149, Percent_Identity=51.006711409396, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=40.6451612903226, Blast_Score=126, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=40.251572327044, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=40.251572327044, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=40.251572327044, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI85726443, Length=157, Percent_Identity=38.8535031847134, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17842; Mature: 17842

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVHDFSEKAMNGKEISLSDYKGKVLLIVNTASKCGLTPQLEGLEAMYKKLGGANFEILG
CCCCCCHHHHCCCCEEEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEEE
FPCNQFLRQDPGSDEEILEFCQMNYGVTFQMFSKIKVKGKDASPLYKYLTEQTGGKKVEW
CCHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCEEEE
NFAKFLIDENGEVVERFSSKMKPEDFEDKVEALVANVK
EHEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNVHDFSEKAMNGKEISLSDYKGKVLLIVNTASKCGLTPQLEGLEAMYKKLGGANFEILG
CCCCCCHHHHCCCCEEEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEEE
FPCNQFLRQDPGSDEEILEFCQMNYGVTFQMFSKIKVKGKDASPLYKYLTEQTGGKKVEW
CCHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCEEEE
NFAKFLIDENGEVVERFSSKMKPEDFEDKVEALVANVK
EHEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]