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The map label for this gene is corA [H]

Identifier: 116689742

GI number: 116689742

Start: 1914256

End: 1915233

Strand: Reverse

Name: corA [H]

Synonym: Bcen2424_1721

Alternate gene names: 116689742

Gene position: 1915233-1914256 (Counterclockwise)

Preceding gene: 116689744

Following gene: 116689740

Centisome position: 54.97

GC content: 62.47

Gene sequence:

>978_bases
ATGCTGATCAACTGTGCTGCTTACCAGGACGGCCGCAAGCTGGCCGATATCGACATCGACGCCATCAGCGATTACGTGTC
GAAGCCCGAATGCTTCGTGTGGGTCGCGCTGAAGGACCCGACGCCCGAGGAAATCGACCTGATGGGCGAGGAATTCGGTT
TGCACGAGCTGGCGCTCGAGGATGCCCGCAAAGGCCATCAGCGGCCGAAGATCGAGGAATACGGCGATTCGCTGTTCGCG
GTGCTGCACACGGTCGAACTCGACGAGGACGACGAATTCAAGGTCGGCGAATTGAACGTATTCGTCGGCCCGAATTACGT
GCTGTCGATCCGCAACCATACCGAGCACGATTTCCGCGACGTGCGCAAGCGTTGCGAGCGCGAGCCGCACTTGTTGCGGG
AGGGTTCGGCGTTCGTGTTCTACGCGTTGATGGACCAGGTCGTCGACCGGTATTTCCCGATCCTCGAAACGCTCGGAGCG
GAACTCGAGGAGCTCGAGGACCGCATCTTCGCGAAGGCGACGCCGGCGTCGTCGCGCGCGATCATCGAGGATCTCTATTC
TCTGAAGCGCCGGCTCGTGCTGCTGTACCAGCACACGGCGCCGCTGATGGAGCCGCTCTCGAAGCTCACCGGCGGGCGCG
TGCCGCAGGTGTGCAGCGGGATGGCGGCTTACTTCCGCGACGTGTACGACCATCTGCAGCGGATCGTGAAGACGATCGAA
GGGCGGCGCGAAATGGTCGTCACGGCGATCCAGGTGAACCTCGGGATGATTTCGCTCGCGGAGAACGAGGTGACCAAGCG
GCTCGGCTCGTTCGCCGCGCTGTTCGCGATACCGACGATGATCGCCGGCATCTACGGGATGAACTTCGCGAACATGCCCG
AGCTGCACCTGAAATACGGGTTCTACGGCTGCATCGCGGTGATGGCCATCGCCGACCTCGCGCTGTGGTGGCGTTTCAAG
CGGGCGGGGTGGCTGTAG

Upstream 100 bases:

>100_bases
ACGCAGCCCGATCATGACCAATATCGGCGTGCCGCGCAAGCCGGGCCGTTCATGCAGCAAACCGGTAAACTGATGCGCAA
ACCGCAACGTCACGAATACC

Downstream 100 bases:

>100_bases
CCAGGCCTCACGCCGGACGCGGCGCGTGCTTGCCGACCACGACGCGCCACGGCCGCACGCGCCACGATTTCACGAGGCCG
TTCTGCACGTACGGATCGGC

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLINCAAYQDGRKLADIDIDAISDYVSKPECFVWVALKDPTPEEIDLMGEEFGLHELALEDARKGHQRPKIEEYGDSLFA
VLHTVELDEDDEFKVGELNVFVGPNYVLSIRNHTEHDFRDVRKRCEREPHLLREGSAFVFYALMDQVVDRYFPILETLGA
ELEELEDRIFAKATPASSRAIIEDLYSLKRRLVLLYQHTAPLMEPLSKLTGGRVPQVCSGMAAYFRDVYDHLQRIVKTIE
GRREMVVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFANMPELHLKYGFYGCIAVMAIADLALWWRFK
RAGWL

Sequences:

>Translated_325_residues
MLINCAAYQDGRKLADIDIDAISDYVSKPECFVWVALKDPTPEEIDLMGEEFGLHELALEDARKGHQRPKIEEYGDSLFA
VLHTVELDEDDEFKVGELNVFVGPNYVLSIRNHTEHDFRDVRKRCEREPHLLREGSAFVFYALMDQVVDRYFPILETLGA
ELEELEDRIFAKATPASSRAIIEDLYSLKRRLVLLYQHTAPLMEPLSKLTGGRVPQVCSGMAAYFRDVYDHLQRIVKTIE
GRREMVVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFANMPELHLKYGFYGCIAVMAIADLALWWRFK
RAGWL
>Mature_325_residues
MLINCAAYQDGRKLADIDIDAISDYVSKPECFVWVALKDPTPEEIDLMGEEFGLHELALEDARKGHQRPKIEEYGDSLFA
VLHTVELDEDDEFKVGELNVFVGPNYVLSIRNHTEHDFRDVRKRCEREPHLLREGSAFVFYALMDQVVDRYFPILETLGA
ELEELEDRIFAKATPASSRAIIEDLYSLKRRLVLLYQHTAPLMEPLSKLTGGRVPQVCSGMAAYFRDVYDHLQRIVKTIE
GRREMVVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFANMPELHLKYGFYGCIAVMAIADLALWWRFK
RAGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=315, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321058, Length=139, Percent_Identity=27.3381294964029, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324442, Length=139, Percent_Identity=28.0575539568345, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37057; Mature: 37057

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINCAAYQDGRKLADIDIDAISDYVSKPECFVWVALKDPTPEEIDLMGEEFGLHELALE
CEEEECCCCCCCEEECCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHH
DARKGHQRPKIEEYGDSLFAVLHTVELDEDDEFKVGELNVFVGPNYVLSIRNHTEHDFRD
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEEECCCCCHHHHH
VRKRCEREPHLLREGSAFVFYALMDQVVDRYFPILETLGAELEELEDRIFAKATPASSRA
HHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIEDLYSLKRRLVLLYQHTAPLMEPLSKLTGGRVPQVCSGMAAYFRDVYDHLQRIVKTIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GRREMVVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFANMPELHLKYG
CCHHHEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FYGCIAVMAIADLALWWRFKRAGWL
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLINCAAYQDGRKLADIDIDAISDYVSKPECFVWVALKDPTPEEIDLMGEEFGLHELALE
CEEEECCCCCCCEEECCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHH
DARKGHQRPKIEEYGDSLFAVLHTVELDEDDEFKVGELNVFVGPNYVLSIRNHTEHDFRD
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEEECCCCCHHHHH
VRKRCEREPHLLREGSAFVFYALMDQVVDRYFPILETLGAELEELEDRIFAKATPASSRA
HHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIEDLYSLKRRLVLLYQHTAPLMEPLSKLTGGRVPQVCSGMAAYFRDVYDHLQRIVKTIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GRREMVVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFANMPELHLKYG
CCHHHEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FYGCIAVMAIADLALWWRFKRAGWL
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]