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The map label for this gene is modB [H]

Identifier: 116689709

GI number: 116689709

Start: 1876027

End: 1876950

Strand: Direct

Name: modB [H]

Synonym: Bcen2424_1687

Alternate gene names: 116689709

Gene position: 1876027-1876950 (Clockwise)

Preceding gene: 116689708

Following gene: 116689710

Centisome position: 53.85

GC content: 66.67

Gene sequence:

>924_bases
ATGGCGACCGACGATCATGCCGCCCGCACGTGGCCGCCGAAGCACGACGCACCCGATGCGCGGCCCGTCGATGCAAGGAA
ACCGCACCGGATGAAAAGCAATCTCGCTGGCCGCGCATGGAAGGCGCTCGTCTGGGGGCTGATGGCGTTCTTCCTGTTGA
ACGTGATGCTGCTGATCGCGACCGTCGCGGTGAACTCGGTCGCGACGCGTTGGTTCGGCACGCCGTTGCCGCAGGGCTTC
ACGTTGCACTGGTATGCGAAGGCGTGGGACGACTTCCAGCTCGCGAGCGTGCTGTGGGTGACCGTCGAGGTCGTCGGCGC
GGTCGTGCTGCTGTCGATCGCGCTCGGCGTGCCGGCCGCGTATGCGCTCGCGCGCGTGCAGTTCCGCGGCAAGCGCTTCG
CGCTGCTGGTGTTCCTGCTGCCGCTGATGGTGCCGCCCGTCACGTACGGGATTCCGATGGCGACCGTGATGTACAAGATC
GGGCTCGCGGGCACGCTGCCGGGCGTGATCCTCGCGAACCTGGTGCCGGCGCTGCCGTTCGTGATCCTCGTGATGACGCC
GTTCATCGAACAGATCGATCCGAATCTCGAAGCGGCCGCGCGCATCTTCGGCGCGAACACGTGGCGCTATTTCCGCTACG
TGCTGCTGCCGCTGCTGGTGCCCGGCATGCTCGCGGCCGGGCTGCTCGTGCTGGTGCGCACGATCGGGATGTTCGAGCTG
ACGTTCTTCACCGCGGGCCCGAGCACGCAGACGCTCGTCGTCGCGCTGTATTACGCGGTGTTCTCGACCGGCGTGCGCGC
GCCGCAGTCGATCGACGCGATGGCGATGATCTACATGGCCATCACGCTCGTATGGGTCGTGATCGCGCTGCAGTTCGTCA
GTCCAACGCAGCTCGTGAGCCGCGTGAAGCAGGAGCGGCAGTAG

Upstream 100 bases:

>100_bases
TCGCGATCGTGATGGGCTTCGTGCAGTTGCTGGTGGTCGCGTCGATGCTCGGCGCGCGCCGCTTCTTCTATACCGGCGCG
GTGACGGGAGGCAAGGGCTG

Downstream 100 bases:

>100_bases
GCGAGGGCGGCAACGGACGCGCCAGGCGGCCGTGCAATTGGTTACAAATGGATACCGCGCACGACACGCGGACGTTGCAG
ACTACGCGGCGTTCACCCGA

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MATDDHAARTWPPKHDAPDARPVDARKPHRMKSNLAGRAWKALVWGLMAFFLLNVMLLIATVAVNSVATRWFGTPLPQGF
TLHWYAKAWDDFQLASVLWVTVEVVGAVVLLSIALGVPAAYALARVQFRGKRFALLVFLLPLMVPPVTYGIPMATVMYKI
GLAGTLPGVILANLVPALPFVILVMTPFIEQIDPNLEAAARIFGANTWRYFRYVLLPLLVPGMLAAGLLVLVRTIGMFEL
TFFTAGPSTQTLVVALYYAVFSTGVRAPQSIDAMAMIYMAITLVWVVIALQFVSPTQLVSRVKQERQ

Sequences:

>Translated_307_residues
MATDDHAARTWPPKHDAPDARPVDARKPHRMKSNLAGRAWKALVWGLMAFFLLNVMLLIATVAVNSVATRWFGTPLPQGF
TLHWYAKAWDDFQLASVLWVTVEVVGAVVLLSIALGVPAAYALARVQFRGKRFALLVFLLPLMVPPVTYGIPMATVMYKI
GLAGTLPGVILANLVPALPFVILVMTPFIEQIDPNLEAAARIFGANTWRYFRYVLLPLLVPGMLAAGLLVLVRTIGMFEL
TFFTAGPSTQTLVVALYYAVFSTGVRAPQSIDAMAMIYMAITLVWVVIALQFVSPTQLVSRVKQERQ
>Mature_306_residues
ATDDHAARTWPPKHDAPDARPVDARKPHRMKSNLAGRAWKALVWGLMAFFLLNVMLLIATVAVNSVATRWFGTPLPQGFT
LHWYAKAWDDFQLASVLWVTVEVVGAVVLLSIALGVPAAYALARVQFRGKRFALLVFLLPLMVPPVTYGIPMATVMYKIG
LAGTLPGVILANLVPALPFVILVMTPFIEQIDPNLEAAARIFGANTWRYFRYVLLPLLVPGMLAAGLLVLVRTIGMFELT
FFTAGPSTQTLVVALYYAVFSTGVRAPQSIDAMAMIYMAITLVWVVIALQFVSPTQLVSRVKQERQ

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=244, Percent_Identity=27.0491803278689, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787714, Length=206, Percent_Identity=30.0970873786408, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788764, Length=144, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33809; Mature: 33678

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDDHAARTWPPKHDAPDARPVDARKPHRMKSNLAGRAWKALVWGLMAFFLLNVMLLIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAVNSVATRWFGTPLPQGFTLHWYAKAWDDFQLASVLWVTVEVVGAVVLLSIALGVPAA
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YALARVQFRGKRFALLVFLLPLMVPPVTYGIPMATVMYKIGLAGTLPGVILANLVPALPF
HHHHHHHHCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILVMTPFIEQIDPNLEAAARIFGANTWRYFRYVLLPLLVPGMLAAGLLVLVRTIGMFEL
HHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TFFTAGPSTQTLVVALYYAVFSTGVRAPQSIDAMAMIYMAITLVWVVIALQFVSPTQLVS
EEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RVKQERQ
HHHHHCC
>Mature Secondary Structure 
ATDDHAARTWPPKHDAPDARPVDARKPHRMKSNLAGRAWKALVWGLMAFFLLNVMLLIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAVNSVATRWFGTPLPQGFTLHWYAKAWDDFQLASVLWVTVEVVGAVVLLSIALGVPAA
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YALARVQFRGKRFALLVFLLPLMVPPVTYGIPMATVMYKIGLAGTLPGVILANLVPALPF
HHHHHHHHCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILVMTPFIEQIDPNLEAAARIFGANTWRYFRYVLLPLLVPGMLAAGLLVLVRTIGMFEL
HHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
TFFTAGPSTQTLVVALYYAVFSTGVRAPQSIDAMAMIYMAITLVWVVIALQFVSPTQLVS
EEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RVKQERQ
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]