Click here to switch to the map view.

The map label for this gene is cobK [H]

Identifier: 116689699

GI number: 116689699

Start: 1864776

End: 1865507

Strand: Direct

Name: cobK [H]

Synonym: Bcen2424_1677

Alternate gene names: 116689699

Gene position: 1864776-1865507 (Clockwise)

Preceding gene: 116689698

Following gene: 116689700

Centisome position: 53.53

GC content: 72.4

Gene sequence:

>732_bases
ATGAGCCCGCGCATCCTGCTGCTCGGCGGCACCGGCGATGCGCTGAAAATCGCGCGCGCGCTCGGCCCGCATCATGTCTA
TAGTCTCGCCGGTCTCGGCAAGACGCCCGACGACTTGCGCTGCGACGTGCGCGTCGGCGGTTTCGGCGGCGCAGCCGGGC
TTACCGCGTATCTGCGCGACGCGGGTATCGGCCTCGTGATCGACGCAACCCATCCGTATGCCGCGCGAATCAGCGCGAAC
GCCGCGACGGCGACGCGCGACGCAGGCGTGCCGCTGTGGGCGCTGCGCCGCGCGCCGTGGACGCCTCAACCGGGCGACGA
CTGGCGCATGGTCGACGACTGGGCCGGTATCGAGGCCGCGCTCGCGCCGTTCAGGCGCCCGCTGTTCACGCTCGGCCGCG
AACCGCTCGCGCATCTCGACGCGATTCCGCCGCACCAGTTCTGGCTCGTGCGCTGCCTCGATGCGCATCCCGGCAACGCC
CGTGCGCAGGTCGTCGCCGCGCGCGGGCCGTTCACGCCCGACGGCGAGCGCGCGCTGTTCGCGCTGGCTGGCATCGACGT
CGTAGTCAGCAAGAACAGCGGTGGCGCGGCAACCGAGGCCAAGCTCGATGTCGCGCGCGAACGCAGGCTGCCGGTCGTGA
TGCTGCGCCGGCCGCCGCTGCCCGATGCCGACCGCGCGTTCGACTCGGTCACGGCACTCATCGACGCACTCGATCCGGCC
GCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GCGCGCATGCGCTGCGGGTGGCACGCGACATCGTGCCGCCGTCGGTCGCGGTCGAGATGTTCGCGATCGACCGGCAGGGC
CGCTTCGTCGGGGCGGCGCG

Downstream 100 bases:

>100_bases
CGCGACGCAGCGGCCACCCAACGAATTGACGGAGAAATTTCGATGACGGTGTATTTCATCGGCGCGGGCCCAGGCGACCC
GGAGCTGATCACGGTGAAGG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSPRILLLGGTGDALKIARALGPHHVYSLAGLGKTPDDLRCDVRVGGFGGAAGLTAYLRDAGIGLVIDATHPYAARISAN
AATATRDAGVPLWALRRAPWTPQPGDDWRMVDDWAGIEAALAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNA
RAQVVAARGPFTPDGERALFALAGIDVVVSKNSGGAATEAKLDVARERRLPVVMLRRPPLPDADRAFDSVTALIDALDPA
ARA

Sequences:

>Translated_243_residues
MSPRILLLGGTGDALKIARALGPHHVYSLAGLGKTPDDLRCDVRVGGFGGAAGLTAYLRDAGIGLVIDATHPYAARISAN
AATATRDAGVPLWALRRAPWTPQPGDDWRMVDDWAGIEAALAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNA
RAQVVAARGPFTPDGERALFALAGIDVVVSKNSGGAATEAKLDVARERRLPVVMLRRPPLPDADRAFDSVTALIDALDPA
ARA
>Mature_242_residues
SPRILLLGGTGDALKIARALGPHHVYSLAGLGKTPDDLRCDVRVGGFGGAAGLTAYLRDAGIGLVIDATHPYAARISANA
ATATRDAGVPLWALRRAPWTPQPGDDWRMVDDWAGIEAALAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNAR
AQVVAARGPFTPDGERALFALAGIDVVVSKNSGGAATEAKLDVARERRLPVVMLRRPPLPDADRAFDSVTALIDALDPAA
RA

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 25758; Mature: 25627

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRILLLGGTGDALKIARALGPHHVYSLAGLGKTPDDLRCDVRVGGFGGAAGLTAYLRD
CCCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
AGIGLVIDATHPYAARISANAATATRDAGVPLWALRRAPWTPQPGDDWRMVDDWAGIEAA
CCCEEEEECCCCCEEEEECCCCCCCCCCCCCEEEHHCCCCCCCCCCCCEEEHHHCCHHHH
LAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNARAQVVAARGPFTPDGERALF
HHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEE
ALAGIDVVVSKNSGGAATEAKLDVARERRLPVVMLRRPPLPDADRAFDSVTALIDALDPA
EEECEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHH
ARA
HCC
>Mature Secondary Structure 
SPRILLLGGTGDALKIARALGPHHVYSLAGLGKTPDDLRCDVRVGGFGGAAGLTAYLRD
CCCEEEEECCCHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
AGIGLVIDATHPYAARISANAATATRDAGVPLWALRRAPWTPQPGDDWRMVDDWAGIEAA
CCCEEEEECCCCCEEEEECCCCCCCCCCCCCEEEHHCCCCCCCCCCCCEEEHHHCCHHHH
LAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNARAQVVAARGPFTPDGERALF
HHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEE
ALAGIDVVVSKNSGGAATEAKLDVARERRLPVVMLRRPPLPDADRAFDSVTALIDALDPA
EEECEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHH
ARA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]