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The map label for this gene is rnr [H]

Identifier: 116689568

GI number: 116689568

Start: 1711322

End: 1713805

Strand: Direct

Name: rnr [H]

Synonym: Bcen2424_1546

Alternate gene names: 116689568

Gene position: 1711322-1713805 (Clockwise)

Preceding gene: 116689561

Following gene: 116689569

Centisome position: 49.12

GC content: 66.79

Gene sequence:

>2484_bases
TTGAGCAAATATCCGTACCCCATTCCGAGCCGTGAAGAGATTCTCGGCGTGCTGCGTACGAGCGACGCGCCGCTGGCCGC
CAACGACATCGCCGAAGCCCTGTCGATCAAGCGTCAAGAGCGCGAGGGGTTCTTCCGGCGTGTCGCCGCGATGGAGCGCG
ACGGCCAGATCCGCCTCGACAAGCGTGGCCACTACCAGTTGACCCATCCGTCGAATTTCGTCGCCGGTCGCGTGCAGGGG
CATCGCGACGGCTACGGGTTCGTGATTCGCGACGACGGCCAGGACGACCTGTTCTTGCCGAACGGCGAAATGCAGAAAGT
GATGCACAACGACCGCGTGCTCGCGCGGATCGTCGGCTACGATCGCCGCGGCCGGCCGGAAGGGCACGTCGTCGAAGTCA
CCGAACGCGCGAACAAGCGCGTAATCGGTCGCCTGCTGAACGAGAACGGTGCGCTGATCGTCGCGCCGGAAGACAAGCGC
ATCGGCCACGACATCCTGATCACGCAGAACGTGAAGAAGGCGAAGGTCGGGCAGGTCGTCGTCGTCGAACTGACCGATTT
CCCGAGCCGTCATTCGCAGCCGCTCGGCCGTGTCGTCGAAGTGCTCGGCGATATCGACGATCCGGGCATGGAAATCGAAA
TCGCGGTGCGCAAGTACGGCGTGCCGCATGAATTCAGCCAGCCGGCGCTCGACGAAGCCGCGGCGCTGCCCGACAAGGTG
CGCCCGGCCGATCTGCGTTTCCGCGTCGACCTGCGCGACGTGCCGCTCGTGACGATCGACGGCGAGGACGCCCGAGACTT
CGACGATGCCGTCTACTGCGAGCCGGTCAAGGTCGGTCGCGGCGACGGCTTCCGGTTGATCGTCGCGATCGCCGACGTGT
CGCACTACGTACAGCCGGGTAGCGGGCTCGATGCCGACGCGCTGGAGCGCAGCACGTCGGTCTACTTCCCGCGTCGCGTG
ATTCCGATGCTGCCGGAGAAGCTGTCGAACGGCCTCTGTTCGCTGAATCCGCAGGTCGATCGCTGCGTGCTCGCGTGCGA
CATGGTGATCACCGCGCGCGGCGAGATCAAGGCCTACCAGTTCTACCCGGCCGTGATCCATTCGGCGGCGCGCCTCACGT
ACACCGAAGTCGCGGCCGTGCTGTCGAACACGAAGGGGCCGGAGGCCGCGCGCCGCGCCGATCTGCTGCCGCACCTGCAG
GATCTGTACGGCGTCTACAAGTCGCTGTTCGCCGCCCGTCAAAAGCGCGGTGCGATCGACTTCGACACGACCGAGACCTA
CATCGTCTGCAACTCGCAGGGCAAGATCGAGCAGATCGTGCCGCGTCAGCGCAACGACGCGCACAAGCTGATCGAGGAAT
GCATGCTGGCCGCGAACGTCTGCGCGGCCGATTTCCTGAAGCGCAACAAGCATCCGGGCCTGTACCGCGTGCACGCGGGG
CCGACGCCGGAGAAGCTCGAGAACCTGCGCGCGTTCCTGCGCGGCATGGGCCTGTCGCTCGGCGGCGGCGACAAGCCGCA
TGCGAGCGACTACGCGGCGCTGATGGCGCAGATCCGCGACCGGCCGGACGCGCAGATGCTGCAGCCGATGCTGCTGCGCT
CGATGCAGCAGGCCGTCTACAGCCCGGACAACATCGGTCACTTCGGCCTCGCGTACGAGGCGTACGCGCACTTCACGAGC
CCGATCCGCCGCTATCCGGACCTGCTCACGCACCGTGCGATCTACGCGATCCTGTCGGGCAAGAAGTACACGCCGAAGGC
GCCGGAAGGCTTCGAGCTGAACACCGCGCTGTCGCCGCGCGCCCGCGCGATGCAGCAGGCCGACGACGAAGCGCGCAACC
GCTCGCGCTCGAACACGGCGATCTGGGAAGAGCTCGGCTTGCACTGCTCGGCGAACGAGCGCCGTGCGGACGAGGCGTCG
CGCGACGTCGAAGCGTGGCTCAAGTGCTACTTCATGCGCGACAAGCTCGGCGAGGAGTATGGCGGGATGGTGAACGGCGT
GACGTCGTTCGGCATCTTCGTGCAGCTCGACACGCTGTTCATCGAAGGGCTTGTGCACGTGACGGAACTCGGCTCGGACT
ACTTCCAGTACGACGAGATCAAGAACGAGTTGCGCGGCGAACGCACGGGCATCCGCTATCGCCTGTCGGATCGCGTGCGC
GTGCAGGTGAGCCGCGTCGATCTCGATGCGCGCAAGATCGATTTCCGCCTCGTGCGCGATACGCCGGTGAAGGCGCCGCG
TCCGTCGCCCGCGCCAGCTGCCGGCATCGATCGCAATGGCAGCGGCAATGGCCCGCGCGTGCGTGCGCTGCCGCCGGTGG
AGGAAACCGTGCCGCGTCGCAAGAAGGCCGCGAGCGCGCCGAGCGTCGCGGTGCAGGAAGCGCGCGCCGCGCGTGGCGCC
GCGAAGAAGAAGAGCGGCGGTGCCGGCGGTGGCGCACCCGCGAAGCCGACTGCGAAGAAGGCTCGCGCCCGCAAGAAGTA
TTGA

Upstream 100 bases:

>100_bases
AATGACCCGCCGCCGTCAATATAGAACTGTCTGACGGACACCTCTATGTTGATGCCGTGCACCATCAGTCAACGCAACGA
GAACAATCATCGACAAACCC

Downstream 100 bases:

>100_bases
GTGTTCGGGGCGGCGTACGCGCACGCCCTGCAGTATCGAGAGACGCCGCGTCACCGGTCATCGGCCGGCCACGCGGCGCT
TTCCTTTTCCATGGATCGCG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 827; Mature: 826

Protein sequence:

>827_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGFRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQ
DLYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYTPKAPEGFELNTALSPRARAMQQADDEARNRSRSNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPAPAAGIDRNGSGNGPRVRALPPVEETVPRRKKAASAPSVAVQEARAARGA
AKKKSGGAGGGAPAKPTAKKARARKKY

Sequences:

>Translated_827_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGFRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQ
DLYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYTPKAPEGFELNTALSPRARAMQQADDEARNRSRSNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPAPAAGIDRNGSGNGPRVRALPPVEETVPRRKKAASAPSVAVQEARAARGA
AKKKSGGAGGGAPAKPTAKKARARKKY
>Mature_826_residues
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGH
RDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRI
GHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKVR
PADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGFRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRVI
PMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQD
LYGVYKSLFAARQKRGAIDFDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAGP
TPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYEAYAHFTSP
IRRYPDLLTHRAIYAILSGKKYTPKAPEGFELNTALSPRARAMQQADDEARNRSRSNTAIWEELGLHCSANERRADEASR
DVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVRV
QVSRVDLDARKIDFRLVRDTPVKAPRPSPAPAAGIDRNGSGNGPRVRALPPVEETVPRRKKAASAPSVAVQEARAARGAA
KKKSGGAGGGAPAKPTAKKARARKKY

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=487, Percent_Identity=29.1581108829569, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI190014625, Length=487, Percent_Identity=29.1581108829569, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI134288890, Length=440, Percent_Identity=30.6818181818182, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI219521928, Length=648, Percent_Identity=26.0802469135802, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI19115966, Length=648, Percent_Identity=26.0802469135802, Blast_Score=157, Evalue=3e-38,
Organism=Escherichia coli, GI87082383, Length=749, Percent_Identity=48.5981308411215, Blast_Score=689, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=700, Percent_Identity=27.2857142857143, Blast_Score=201, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI212645896, Length=416, Percent_Identity=31.0096153846154, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=528, Percent_Identity=29.1666666666667, Blast_Score=169, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6324552, Length=654, Percent_Identity=25.6880733944954, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24649634, Length=468, Percent_Identity=28.6324786324786, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24654592, Length=437, Percent_Identity=29.0617848970252, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI19922976, Length=437, Percent_Identity=29.5194508009153, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24654597, Length=437, Percent_Identity=29.5194508009153, Blast_Score=143, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91874; Mature: 91743

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCC
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGFRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECEEEECCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEE
FYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQDLYGVYKSLFAARQKRGAID
EHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKAPEGFELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHH
ARAMQQADDEARNRSRSNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPAPAAGIDRNGSGNGPRVRALPPVEETVPRR
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCHH
KKAASAPSVAVQEARAARGAAKKKSGGAGGGAPAKPTAKKARARKKY
HHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQPALDEAAALPDKV
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCC
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGDGFRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECEEEECCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDMVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEE
FYPAVIHSAARLTYTEVAAVLSNTKGPEAARRADLLPHLQDLYGVYKSLFAARQKRGAID
EHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNSQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRNKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
PTPEKLENLRAFLRGMGLSLGGGDKPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILSGKKYTPKAPEGFELNTALSPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHH
ARAMQQADDEARNRSRSNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPSPAPAAGIDRNGSGNGPRVRALPPVEETVPRR
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCHH
KKAASAPSVAVQEARAARGAAKKKSGGAGGGAPAKPTAKKARARKKY
HHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]