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The map label for this gene is ychM [C]

Identifier: 116689561

GI number: 116689561

Start: 1701105

End: 1702820

Strand: Direct

Name: ychM [C]

Synonym: Bcen2424_1539

Alternate gene names: 116689561

Gene position: 1701105-1702820 (Clockwise)

Preceding gene: 116689560

Following gene: 116689568

Centisome position: 48.83

GC content: 69.35

Gene sequence:

>1716_bases
ATGACGACCGCTCCGATTCGCCCCGACGCCGGCCCGCAGCATCCCGACCATTTCGTCGCGCTCGACACGCCGCCCGCGCC
GCGCCCGTGGCGCGTCAGCCTCGATGCGCTGGCCGGCCTGTCGATTGCCGGCCTGCTGATTCCCGAGGCGGTCGCGTATG
CGGGGCTGGCCAACCTGCCGCCGCAGGCCGGCCTGATCGCGCTGCTGTCAGGGCTCGTCGTCTATGCGTTGACCGGCAGC
AGCCGCTTCGCGATCGTATCGTCGACGTCATCGTCGGCCGCGGTGCTCGCGGCGACCGTGCTCGCCGAATCGGGGATGGC
GCTGGCCGCGCAGCTCGCGCTCGCGGCGGCGCTCGTCGCGACGACCGGCGTGCTGTTCATCCTGGCCGGTGTCGCGCGGC
TCGGCGGCATGTCGGATTTCGTCGCGCGGCCCGTGCTGCGCGGCTTCACGTTCGGTCTCGCGCTGACGATCGTCATCAAG
CAGTTGCCGAAGATTCTCGCGATTTCCGTACAGCACAGCGATGCGCCGCACGTCGCGCTCGACCTGCTCGCCGGTGCGCC
GCACGCGAATCTCGCGAGCGTCGTGGTCGGTGCGACGGCACTTGCGCTGTTGTTCGTGCTCGGCCGCGGCGCGCGCGTGC
CCGCGACGCTCGTCGTGATCGTGCTGTCGATCGCGGCGGGTTACGTGGTCGACTGGCAGCGGTACGGAATCGCGATCGTC
GGCCATATCGATTTCCGGCACCTCGAATTCGGCTTGCCGCATCTCGACCGCAATGCGTGGATGCAGACGGTCGAGCTCGC
ATTTGCGCTGATGCTGATCCTGTATGCGGAGTCGTACGGTTCGATCCGCAACTTCGCGCTGAAGCATGGCGATACCGTGT
CGCCGAACCGCGACCTCGTCGCGCTCGGCTGCGCGAACCTCGTGTCGGGGCTGCTGCACGGGATGCCGGTCGGCGCCGGC
TATTCGGCGACGTCGGCGAACGAGGCGGCCGGTGCGCAGTCGCGTTTGGCGGGGATGTGGGCGGCCGGCGTGGTCGCGCT
GATCGTCTGGCTGCTGCTGCCGCAACTCGCGCGTACGCCCGAGCCCGTGCTCGCGGCCATCGTGATCTTCGCGGTCAGCC
ATTCGCTGCATCCGTCCGTGTTCCGGCCGTACTGGGCTTGGCATCGCGACCGGCTCGTCGTGATCGCGGCGCTGCTCGCG
GTGCTCGTGCTAGGCGTGCTGCACGGCCTGCTCGCGGCGATCGGCGTGAGCCTGCTGCTGACGCTGCGCAAGCTGTCCGA
GCCGAACGTCAGCGTGCTCGGCCGGTTGCGCGACAGCCACGATTTCGTCGACGTCGCGAGTCACGCCGATGCGAAACCGG
TGCCCGGCGTGCTGATCGTGCGGCCCGAGGCGCAGCTGTTCTTCGCGAATGCGGACCGGATGCTCAATCGCGTGCGGGCG
CTGATGAAGGCCGCGCCGGACACCCATATCGTGATGGTGAGTCTCGAGGAAACGCCGGACGTCGACGGCACGACGATCGA
ATCGTTGCGCACGTTCGCGGCCGAATGCGCGGCGCGCGGGCTGCGGCTCGCGCTCGTCCGGCTCAAGACGCACGCGCTGC
ATGCGCTGCGCCGTGCGGCGGACGATACGTTGCACGACGACGCGATGTCGGAGCTCAGCGTCGACGAGAGTCTGCAACTG
CTGCAGGCCGGCAAACCGCCGGACGGCAGCGAGTGA

Upstream 100 bases:

>100_bases
TCGCGCTGCAGCGCGCGCACGAGCAGGATGCGCGCTATCTGCCCGGCTGGTCGGGCGTGATTGCCGTGAAGCCCTGACCG
GCTCACGGCTCCGCCGTCTC

Downstream 100 bases:

>100_bases
CGGCGCGGCGCGTCGGCGCCGCCTATTGCGACAGCGCGGCGTTGGCGGTGGTGCGTTCGATCATGTCGGCTACTTCCGCA
GCCGTCGGCGCATAGGCGCC

Product: sulphate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTTAPIRPDAGPQHPDHFVALDTPPAPRPWRVSLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGS
SRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVATTGVLFILAGVARLGGMSDFVARPVLRGFTFGLALTIVIK
QLPKILAISVQHSDAPHVALDLLAGAPHANLASVVVGATALALLFVLGRGARVPATLVVIVLSIAAGYVVDWQRYGIAIV
GHIDFRHLEFGLPHLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQSRLAGMWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLA
VLVLGVLHGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
LMKAAPDTHIVMVSLEETPDVDGTTIESLRTFAAECAARGLRLALVRLKTHALHALRRAADDTLHDDAMSELSVDESLQL
LQAGKPPDGSE

Sequences:

>Translated_571_residues
MTTAPIRPDAGPQHPDHFVALDTPPAPRPWRVSLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGS
SRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVATTGVLFILAGVARLGGMSDFVARPVLRGFTFGLALTIVIK
QLPKILAISVQHSDAPHVALDLLAGAPHANLASVVVGATALALLFVLGRGARVPATLVVIVLSIAAGYVVDWQRYGIAIV
GHIDFRHLEFGLPHLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQSRLAGMWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLA
VLVLGVLHGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
LMKAAPDTHIVMVSLEETPDVDGTTIESLRTFAAECAARGLRLALVRLKTHALHALRRAADDTLHDDAMSELSVDESLQL
LQAGKPPDGSE
>Mature_570_residues
TTAPIRPDAGPQHPDHFVALDTPPAPRPWRVSLDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALLSGLVVYALTGSS
RFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVATTGVLFILAGVARLGGMSDFVARPVLRGFTFGLALTIVIKQ
LPKILAISVQHSDAPHVALDLLAGAPHANLASVVVGATALALLFVLGRGARVPATLVVIVLSIAAGYVVDWQRYGIAIVG
HIDFRHLEFGLPHLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAGY
SATSANEAAGAQSRLAGMWAAGVVALIVWLLLPQLARTPEPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLAV
LVLGVLHGLLAAIGVSLLLTLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRAL
MKAAPDTHIVMVSLEETPDVDGTTIESLRTFAAECAARGLRLALVRLKTHALHALRRAADDTLHDDAMSELSVDESLQLL
QAGKPPDGSE

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721257, Length=459, Percent_Identity=27.6688453159041, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI94721259, Length=459, Percent_Identity=27.6688453159041, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI94721253, Length=459, Percent_Identity=27.6688453159041, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI94721255, Length=459, Percent_Identity=27.6688453159041, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI39752683, Length=481, Percent_Identity=24.1164241164241, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI45827800, Length=481, Percent_Identity=24.1164241164241, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI217272867, Length=509, Percent_Identity=23.5756385068762, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI16418413, Length=509, Percent_Identity=23.5756385068762, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI47131207, Length=507, Percent_Identity=26.6272189349112, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI20336272, Length=507, Percent_Identity=26.6272189349112, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI269784651, Length=478, Percent_Identity=23.8493723849372, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI4557535, Length=486, Percent_Identity=25.3086419753086, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI45827802, Length=439, Percent_Identity=23.4624145785877, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI100913030, Length=487, Percent_Identity=23.4086242299795, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI4505697, Length=492, Percent_Identity=21.9512195121951, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI20336282, Length=490, Percent_Identity=21.2244897959184, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI16306483, Length=490, Percent_Identity=21.2244897959184, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI262206105, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206075, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206069, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206063, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI65506789, Length=405, Percent_Identity=27.6543209876543, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87081859, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551690, Length=514, Percent_Identity=25.2918287937743, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI86564196, Length=502, Percent_Identity=22.3107569721116, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI86565215, Length=506, Percent_Identity=22.9249011857708, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI193203292, Length=503, Percent_Identity=23.0616302186879, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86564876, Length=525, Percent_Identity=20.952380952381, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17566848, Length=571, Percent_Identity=23.6427320490368, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562578, Length=522, Percent_Identity=22.9885057471264, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=488, Percent_Identity=23.155737704918, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319771, Length=455, Percent_Identity=22.1978021978022, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24649801, Length=540, Percent_Identity=24.2592592592593, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24651449, Length=446, Percent_Identity=25.1121076233184, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24666186, Length=512, Percent_Identity=25, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19922482, Length=524, Percent_Identity=22.5190839694656, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24663084, Length=438, Percent_Identity=25.5707762557078, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357695, Length=438, Percent_Identity=25.5707762557078, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358229, Length=444, Percent_Identity=25, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358633, Length=569, Percent_Identity=21.9683655536028, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI85815873, Length=434, Percent_Identity=23.2718894009217, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355087, Length=243, Percent_Identity=20.5761316872428, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24647160, Length=243, Percent_Identity=20.5761316872428, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59937; Mature: 59806

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPIRPDAGPQHPDHFVALDTPPAPRPWRVSLDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEHHHHHCHHHHHHHHHHHHHHHCCCCCC
PQAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVA
CCCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TTGVLFILAGVARLGGMSDFVARPVLRGFTFGLALTIVIKQLPKILAISVQHSDAPHVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHH
DLLAGAPHANLASVVVGATALALLFVLGRGARVPATLVVIVLSIAAGYVVDWQRYGIAIV
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEHHHCCEEEE
GHIDFRHLEFGLPHLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDTVSPNRDLV
EECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQSRLAGMWAAGVVALIVWLLLPQLARTP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLAVLVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
HHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LMKAAPDTHIVMVSLEETPDVDGTTIESLRTFAAECAARGLRLALVRLKTHALHALRRAA
HHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DDTLHDDAMSELSVDESLQLLQAGKPPDGSE
HHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTAPIRPDAGPQHPDHFVALDTPPAPRPWRVSLDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEHHHHHCHHHHHHHHHHHHHHHCCCCCC
PQAGLIALLSGLVVYALTGSSRFAIVSSTSSSAAVLAATVLAESGMALAAQLALAAALVA
CCCCHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TTGVLFILAGVARLGGMSDFVARPVLRGFTFGLALTIVIKQLPKILAISVQHSDAPHVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHH
DLLAGAPHANLASVVVGATALALLFVLGRGARVPATLVVIVLSIAAGYVVDWQRYGIAIV
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEHHHCCEEEE
GHIDFRHLEFGLPHLDRNAWMQTVELAFALMLILYAESYGSIRNFALKHGDTVSPNRDLV
EECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQSRLAGMWAAGVVALIVWLLLPQLARTP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EPVLAAIVIFAVSHSLHPSVFRPYWAWHRDRLVVIAALLAVLVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRKLSEPNVSVLGRLRDSHDFVDVASHADAKPVPGVLIVRPEAQLFFANADRMLNRVRA
HHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LMKAAPDTHIVMVSLEETPDVDGTTIESLRTFAAECAARGLRLALVRLKTHALHALRRAA
HHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DDTLHDDAMSELSVDESLQLLQAGKPPDGSE
HHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]