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The map label for this gene is hfq [H]

Identifier: 116689553

GI number: 116689553

Start: 1693208

End: 1693786

Strand: Reverse

Name: hfq [H]

Synonym: Bcen2424_1531

Alternate gene names: 116689553

Gene position: 1693786-1693208 (Counterclockwise)

Preceding gene: 116689555

Following gene: 116689538

Centisome position: 48.62

GC content: 69.78

Gene sequence:

>579_bases
ATGGCCAATCCCGCAGAATCCCATCCGCAAAACGACTTCATCAATTCGGCGCGCAAGGAACGTAAGCGTGTTGAAATCTA
TCTCGTCAACGGCATTCGTCTGACGGGGTGTATCGAGTCGTTCGACCAGTATCTGGTGATGCTGCGCACCCCCGTGGGTC
TGCAAGGCATCTACAAGCGTGCGATTTCCACGATCCAGCTCGACACGGGCGGCTCGCGCCCCGGCGGCGGCGGCCCCCGC
GGCCCGCGCACCGGTGGTCGCCCCGGCGGCCGTGAAGGCGGCGGTCACAGCCCGTACGGCTCGCACGGCGGCCCGCGCGA
ATCGCGCGGCGACGGCGGCTACGGCTCCCGCGAGCCGCGTGAAGGGTACGGTTCGCGTGAACCGCGCGAGGGTTACGGCT
CACGTGAGCCGCGCGAAGGCTACGGCGCCCCCCGCGAGCCGCGTGAACCGCGCGAAAGCTACGGCGCGCCGCGCGACACC
GGCGACGCATCCGGCAACGTCGCACCGTCGGATTCCCGCGGCGGCAACGGGCCGGTCATCGTGACGCGCCGCCGGCGAAT
CGTGCCGGACGGCCAGTAA

Upstream 100 bases:

>100_bases
CCCTTATCGAACAGGGTAGAATTCCGCCAAACGGCTTGTGGACGAACACGCCACACACACGCACAACATATTCTCTGACG
CAGGCTCCTGCCGCACCTCA

Downstream 100 bases:

>100_bases
AACAAAAAGGGCAAGCCAACCGGCTTGCCCTTTTCACTTGTACGGCCGGCGCGGCACGTCGCCGCACCGTCGTTACCGGG
TTCAGCGTGCCGTCGTCGGC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGGGPR
GPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPREGYGSREPREGYGSREPREGYGAPREPREPRESYGAPRDT
GDASGNVAPSDSRGGNGPVIVTRRRRIVPDGQ

Sequences:

>Translated_192_residues
MANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGGGPR
GPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPREGYGSREPREGYGSREPREGYGAPREPREPRESYGAPRDT
GDASGNVAPSDSRGGNGPVIVTRRRRIVPDGQ
>Mature_191_residues
ANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKRAISTIQLDTGGSRPGGGGPRG
PRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPREGYGSREPREGYGSREPREGYGAPREPREPRESYGAPRDTG
DASGNVAPSDSRGGNGPVIVTRRRRIVPDGQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=56, Percent_Identity=55.3571428571429, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 20585; Mature: 20454

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKR
CCCCCCCCCCHHHHHHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
AISTIQLDTGGSRPGGGGPRGPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPR
HHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EGYGSREPREGYGSREPREGYGAPREPREPRESYGAPRDTGDASGNVAPSDSRGGNGPVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
VTRRRRIVPDGQ
EECCCCCCCCCC
>Mature Secondary Structure 
ANPAESHPQNDFINSARKERKRVEIYLVNGIRLTGCIESFDQYLVMLRTPVGLQGIYKR
CCCCCCCCCHHHHHHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
AISTIQLDTGGSRPGGGGPRGPRTGGRPGGREGGGHSPYGSHGGPRESRGDGGYGSREPR
HHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EGYGSREPREGYGSREPREGYGAPREPREPRESYGAPRDTGDASGNVAPSDSRGGNGPVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
VTRRRRIVPDGQ
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]