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The map label for this gene is aroE [H]

Identifier: 116622200

GI number: 116622200

Start: 3912758

End: 3913618

Strand: Direct

Name: aroE [H]

Synonym: Acid_3092

Alternate gene names: 116622200

Gene position: 3912758-3913618 (Clockwise)

Preceding gene: 116622199

Following gene: 116622201

Centisome position: 39.26

GC content: 67.6

Gene sequence:

>861_bases
ATGAATGATCGTTCCAGGCTCCTGCTCGGGCTGATCGGCGCCGGCATGCAGAGCTCGCTCACTCCCGCGATGCACGAACG
CGAAGCCGCGGAGCATGGCCTGGTTTGCCTTTACCAGCTGATTGACCTGGCGTGCCTGCGACTGTCCGCGAGCGCGCTGC
CGGAGTTACTCACCGCAGCCGAACGCATGGGGTTCGACGGCCTGAATATCACGCACCCCTGCAAACAATCGGTGCTGCCG
CTGCTTGAGCACGTTTCAAGCGACGCCGCCGCGCTCGGCGCGGTCAACACCGTTGTGCTGCGCGATGGCCGCCGGTGGGG
ACACAACACCGACTGGCTGGCGTTCTCGGCGAGCTTTCGCAGTGGGCTTCCCGGAGCCCCGATCGGGCGGATCGTACAAC
TCGGCGCGGGTGGCGCGGGCGCCGCCACCGCTTACGCCATGCTGAAAATGGGCGCAGGACACATCACCATCGTGGATCTG
GATCCGCCTCGCGCGGATGCGCTGGCGGCACGCTGCGGTGCCCTGTTCCGCGAGGGCCGGATCTCTGTCTCCGCCGATCC
CGCGGCCAGTCTGGCCAGCGCCGACGGTTTGATCCATGCGACGCCGACCGGCATGCACGGGCATCCCGGCAGCGCGATCC
CCGCCGAATTGCTTCGAGGCGATCTGTGGGTTGCCGAGGTCGTCTATTTCCCGCTCGAAACCGAGCTCCTGCGCGCGGCG
CGCGCCGCCGGCTGCCGCACGCTGGACGGGAGCGGCATGGCCGTCCACCAGGCGGTGGAAGCCTTTCGCCTGTTTACAGG
ATTGGAGCCCGATGCCGAGCGGATGCGCCGCCACTTTGCCACGATGGTCCAAGCCCGATGA

Upstream 100 bases:

>100_bases
GATCGCCGGAAACCCGCGGTTGGAATCGTTGGTCCTGCCGATTGTCCGTGCCCGAGTGGACGGGCTTGCGATCTCGATCG
TACGCTAATGTTGAATCCTG

Downstream 100 bases:

>100_bases
ATACTTCGCCTGCGCTCGCGGCGGCGATGCGCTCCCGCACCCGATTCCGCATTCTCGCCCTGATCTCGGTGGGGACCATG
ATCAACTACCTGGATCGCAC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNDRSRLLLGLIGAGMQSSLTPAMHEREAAEHGLVCLYQLIDLACLRLSASALPELLTAAERMGFDGLNITHPCKQSVLP
LLEHVSSDAAALGAVNTVVLRDGRRWGHNTDWLAFSASFRSGLPGAPIGRIVQLGAGGAGAATAYAMLKMGAGHITIVDL
DPPRADALAARCGALFREGRISVSADPAASLASADGLIHATPTGMHGHPGSAIPAELLRGDLWVAEVVYFPLETELLRAA
RAAGCRTLDGSGMAVHQAVEAFRLFTGLEPDAERMRRHFATMVQAR

Sequences:

>Translated_286_residues
MNDRSRLLLGLIGAGMQSSLTPAMHEREAAEHGLVCLYQLIDLACLRLSASALPELLTAAERMGFDGLNITHPCKQSVLP
LLEHVSSDAAALGAVNTVVLRDGRRWGHNTDWLAFSASFRSGLPGAPIGRIVQLGAGGAGAATAYAMLKMGAGHITIVDL
DPPRADALAARCGALFREGRISVSADPAASLASADGLIHATPTGMHGHPGSAIPAELLRGDLWVAEVVYFPLETELLRAA
RAAGCRTLDGSGMAVHQAVEAFRLFTGLEPDAERMRRHFATMVQAR
>Mature_286_residues
MNDRSRLLLGLIGAGMQSSLTPAMHEREAAEHGLVCLYQLIDLACLRLSASALPELLTAAERMGFDGLNITHPCKQSVLP
LLEHVSSDAAALGAVNTVVLRDGRRWGHNTDWLAFSASFRSGLPGAPIGRIVQLGAGGAGAATAYAMLKMGAGHITIVDL
DPPRADALAARCGALFREGRISVSADPAASLASADGLIHATPTGMHGHPGSAIPAELLRGDLWVAEVVYFPLETELLRAA
RAAGCRTLDGSGMAVHQAVEAFRLFTGLEPDAERMRRHFATMVQAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=285, Percent_Identity=28.0701754385965, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=28.7769784172662, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893 [H]

Pfam domain/function: PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30141; Mature: 30141

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRSRLLLGLIGAGMQSSLTPAMHEREAAEHGLVCLYQLIDLACLRLSASALPELLTAA
CCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMGFDGLNITHPCKQSVLPLLEHVSSDAAALGAVNTVVLRDGRRWGHNTDWLAFSASFR
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCCCCCCEEEEECHHH
SGLPGAPIGRIVQLGAGGAGAATAYAMLKMGAGHITIVDLDPPRADALAARCGALFREGR
CCCCCCCHHHHEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
ISVSADPAASLASADGLIHATPTGMHGHPGSAIPAELLRGDLWVAEVVYFPLETELLRAA
EEECCCCHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHH
RAAGCRTLDGSGMAVHQAVEAFRLFTGLEPDAERMRRHFATMVQAR
HHCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDRSRLLLGLIGAGMQSSLTPAMHEREAAEHGLVCLYQLIDLACLRLSASALPELLTAA
CCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMGFDGLNITHPCKQSVLPLLEHVSSDAAALGAVNTVVLRDGRRWGHNTDWLAFSASFR
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCCCCCCEEEEECHHH
SGLPGAPIGRIVQLGAGGAGAATAYAMLKMGAGHITIVDLDPPRADALAARCGALFREGR
CCCCCCCHHHHEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
ISVSADPAASLASADGLIHATPTGMHGHPGSAIPAELLRGDLWVAEVVYFPLETELLRAA
EEECCCCHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHH
RAAGCRTLDGSGMAVHQAVEAFRLFTGLEPDAERMRRHFATMVQAR
HHCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12692562; 11572948 [H]