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The map label for this gene is dgoT [H]

Identifier: 116622201

GI number: 116622201

Start: 3913615

End: 3914898

Strand: Direct

Name: dgoT [H]

Synonym: Acid_3093

Alternate gene names: 116622201

Gene position: 3913615-3914898 (Clockwise)

Preceding gene: 116622200

Following gene: 116622204

Centisome position: 39.27

GC content: 63.79

Gene sequence:

>1284_bases
ATGAATACTTCGCCTGCGCTCGCGGCGGCGATGCGCTCCCGCACCCGATTCCGCATTCTCGCCCTGATCTCGGTGGGGAC
CATGATCAACTACCTGGATCGCACCGTGCTCGGAATCGCGGCGCCATCCATGTCCAGCGAGCTGCACATCTCGCCGGCGG
TGATGGGCATCCTCTTCTCCGCATTCTCGTGGAGCTACGCGGCGGCGCAGATCCCGGGTGGCTGGCTGCTCGACCGGATC
GGCACACGGCTCACGTATTTTCTCGCGGTCACATTCTGGTCATTATTCACGCTCCTACAGGGCTTCGCCGGCGGCATCGC
ATCGCTGCTTGCGTTCCGGCTCGGCCTCGGCGTCAGTGAGGCGCCGTGCTTCCCTACGAACGGCCGCGTGGTGGCCACCT
GGTTCCGCGAGCACGAACGCGCACAGGCAACGGCGGTCTACACGGTCGGAGAATACCTGGGATTGGCCTGCTTCGGCCCG
CTTCTCTTCTGGATCTCGCGGCGCTTCGGCTGGCGATCGCTTTTCTGGGCGGTGGGCACTGCCGGCATCGTCTTCGCCGG
TATCTGGTGGCGGTTGTACCGCGATCCGGAATCCTGCGGGCCCATGGAAAAGCCGGCCGGTGCCGCTCCGGTGAATTGGA
AGCAGGTCCGTCAATTGCTCCGTTACCGGCAGGTCTGGGGCGCCAGCATCGGACAGTTCGGCGGCAATTCCACGCTCGTC
TTCTTTCTTACGTGGTTCCCGACATACCTCGCCAAAGAGCGCCACATGGATTGGATGCGCGCCGGATTCTATGCCATCCT
GCCATTCCTTGCCGCGGCCTGCGGTGTTCTTCTCGGCGGCTGGGGCTCCGATACGCTGCTGAAGCGAACCGGCTCCCGCA
ACCTGGCGCGTAAGCTGCCGCTAATCGCCGGGCTGTTCGGCGCGTCCACGATCATCCTCGCCAATTACGTGAATGGCGAT
GCGCTGGTGATCGCGATCTTCTCGACGGCCTTCTTCTTTCAGGGCATGACCGGGCTGGGCTGGACGGTGATCTCCGACGT
GGCGCCGACCGAGATGCTCGGCGTCACCGGCGGGATCTTCAGTTTCGCCGCCAATCTTGCGGGGGTGGCTACTCCGATTG
TGGTGGGCGCAATCATAGGCGCCACCGGCTCGTTCTACTATGCGCTGGCATATGTGGGAGCGGCGGCGCTTTTAGGCGCG
CTCTCGTACGTGTTCCTGCTGGGCGATGTGGAGCGCATCGTACTGGACCAGACCTACGCTAGTCCCAGCCGGCTGAATAG
CTGA

Upstream 100 bases:

>100_bases
TGGCCGTCCACCAGGCGGTGGAAGCCTTTCGCCTGTTTACAGGATTGGAGCCCGATGCCGAGCGGATGCGCCGCCACTTT
GCCACGATGGTCCAAGCCCG

Downstream 100 bases:

>100_bases
TGGAATTGAAGGTCGCTTTTCAGCGATTGCCAGCGCGGATCGACGCGCAGCGAGATCAGCTCAAAACAACGATCCTGAAA
TGCCTTCGAGAGCCATTCGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNTSPALAAAMRSRTRFRILALISVGTMINYLDRTVLGIAAPSMSSELHISPAVMGILFSAFSWSYAAAQIPGGWLLDRI
GTRLTYFLAVTFWSLFTLLQGFAGGIASLLAFRLGLGVSEAPCFPTNGRVVATWFREHERAQATAVYTVGEYLGLACFGP
LLFWISRRFGWRSLFWAVGTAGIVFAGIWWRLYRDPESCGPMEKPAGAAPVNWKQVRQLLRYRQVWGASIGQFGGNSTLV
FFLTWFPTYLAKERHMDWMRAGFYAILPFLAAACGVLLGGWGSDTLLKRTGSRNLARKLPLIAGLFGASTIILANYVNGD
ALVIAIFSTAFFFQGMTGLGWTVISDVAPTEMLGVTGGIFSFAANLAGVATPIVVGAIIGATGSFYYALAYVGAAALLGA
LSYVFLLGDVERIVLDQTYASPSRLNS

Sequences:

>Translated_427_residues
MNTSPALAAAMRSRTRFRILALISVGTMINYLDRTVLGIAAPSMSSELHISPAVMGILFSAFSWSYAAAQIPGGWLLDRI
GTRLTYFLAVTFWSLFTLLQGFAGGIASLLAFRLGLGVSEAPCFPTNGRVVATWFREHERAQATAVYTVGEYLGLACFGP
LLFWISRRFGWRSLFWAVGTAGIVFAGIWWRLYRDPESCGPMEKPAGAAPVNWKQVRQLLRYRQVWGASIGQFGGNSTLV
FFLTWFPTYLAKERHMDWMRAGFYAILPFLAAACGVLLGGWGSDTLLKRTGSRNLARKLPLIAGLFGASTIILANYVNGD
ALVIAIFSTAFFFQGMTGLGWTVISDVAPTEMLGVTGGIFSFAANLAGVATPIVVGAIIGATGSFYYALAYVGAAALLGA
LSYVFLLGDVERIVLDQTYASPSRLNS
>Mature_427_residues
MNTSPALAAAMRSRTRFRILALISVGTMINYLDRTVLGIAAPSMSSELHISPAVMGILFSAFSWSYAAAQIPGGWLLDRI
GTRLTYFLAVTFWSLFTLLQGFAGGIASLLAFRLGLGVSEAPCFPTNGRVVATWFREHERAQATAVYTVGEYLGLACFGP
LLFWISRRFGWRSLFWAVGTAGIVFAGIWWRLYRDPESCGPMEKPAGAAPVNWKQVRQLLRYRQVWGASIGQFGGNSTLV
FFLTWFPTYLAKERHMDWMRAGFYAILPFLAAACGVLLGGWGSDTLLKRTGSRNLARKLPLIAGLFGASTIILANYVNGD
ALVIAIFSTAFFFQGMTGLGWTVISDVAPTEMLGVTGGIFSFAANLAGVATPIVVGAIIGATGSFYYALAYVGAAALLGA
LSYVFLLGDVERIVLDQTYASPSRLNS

Specific function: Intake of galactonate into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=405, Percent_Identity=25.679012345679, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI148743791, Length=392, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI6912666, Length=385, Percent_Identity=22.5974025974026, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI9966811, Length=404, Percent_Identity=24.009900990099, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI9945322, Length=405, Percent_Identity=23.9506172839506, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI5031955, Length=268, Percent_Identity=25.7462686567164, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4885441, Length=397, Percent_Identity=22.6700251889169, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI21322234, Length=380, Percent_Identity=21.3157894736842, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI148728191, Length=332, Percent_Identity=24.3975903614458, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=43.0588235294118, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=39.6825396825397, Blast_Score=337, Evalue=6e-94,
Organism=Escherichia coli, GI1789515, Length=432, Percent_Identity=41.4351851851852, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI2367379, Length=407, Percent_Identity=32.4324324324324, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI2367193, Length=426, Percent_Identity=26.7605633802817, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788573, Length=431, Percent_Identity=22.969837587007, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=411, Percent_Identity=25.0608272506083, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115533554, Length=411, Percent_Identity=25.0608272506083, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535049, Length=433, Percent_Identity=22.8637413394919, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=368, Percent_Identity=23.9130434782609, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=417, Percent_Identity=23.021582733813, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=409, Percent_Identity=22.0048899755501, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639764, Length=422, Percent_Identity=23.2227488151659, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28573299, Length=395, Percent_Identity=25.8227848101266, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24658658, Length=403, Percent_Identity=23.5732009925558, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573708, Length=378, Percent_Identity=24.3386243386243, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573707, Length=378, Percent_Identity=24.3386243386243, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922400, Length=362, Percent_Identity=25.6906077348066, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550460, Length=427, Percent_Identity=25.9953161592506, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24584153, Length=380, Percent_Identity=23.1578947368421, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654215, Length=362, Percent_Identity=25.6906077348066, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24655255, Length=373, Percent_Identity=26.5415549597855, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24583789, Length=364, Percent_Identity=25.2747252747253, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653727, Length=371, Percent_Identity=24.7978436657682, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920686, Length=308, Percent_Identity=25.6493506493506, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648416, Length=381, Percent_Identity=22.3097112860892, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356189, Length=381, Percent_Identity=22.3097112860892, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46190; Mature: 46190

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSPALAAAMRSRTRFRILALISVGTMINYLDRTVLGIAAPSMSSELHISPAVMGILFS
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AFSWSYAAAQIPGGWLLDRIGTRLTYFLAVTFWSLFTLLQGFAGGIASLLAFRLGLGVSE
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APCFPTNGRVVATWFREHERAQATAVYTVGEYLGLACFGPLLFWISRRFGWRSLFWAVGT
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AGIVFAGIWWRLYRDPESCGPMEKPAGAAPVNWKQVRQLLRYRQVWGASIGQFGGNSTLV
HHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCEEE
FFLTWFPTYLAKERHMDWMRAGFYAILPFLAAACGVLLGGWGSDTLLKRTGSRNLARKLP
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHH
LIAGLFGASTIILANYVNGDALVIAIFSTAFFFQGMTGLGWTVISDVAPTEMLGVTGGIF
HHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHCCHHHH
SFAANLAGVATPIVVGAIIGATGSFYYALAYVGAAALLGALSYVFLLGDVERIVLDQTYA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPSRLNS
CHHCCCC
>Mature Secondary Structure
MNTSPALAAAMRSRTRFRILALISVGTMINYLDRTVLGIAAPSMSSELHISPAVMGILFS
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AFSWSYAAAQIPGGWLLDRIGTRLTYFLAVTFWSLFTLLQGFAGGIASLLAFRLGLGVSE
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APCFPTNGRVVATWFREHERAQATAVYTVGEYLGLACFGPLLFWISRRFGWRSLFWAVGT
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AGIVFAGIWWRLYRDPESCGPMEKPAGAAPVNWKQVRQLLRYRQVWGASIGQFGGNSTLV
HHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCEEE
FFLTWFPTYLAKERHMDWMRAGFYAILPFLAAACGVLLGGWGSDTLLKRTGSRNLARKLP
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHH
LIAGLFGASTIILANYVNGDALVIAIFSTAFFFQGMTGLGWTVISDVAPTEMLGVTGGIF
HHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHCCHHHH
SFAANLAGVATPIVVGAIIGATGSFYYALAYVGAAALLGALSYVFLLGDVERIVLDQTYA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPSRLNS
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]