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The map label for this gene is iorB [H]

Identifier: 116622017

GI number: 116622017

Start: 3679661

End: 3681988

Strand: Reverse

Name: iorB [H]

Synonym: Acid_2902

Alternate gene names: 116622017

Gene position: 3681988-3679661 (Counterclockwise)

Preceding gene: 116622018

Following gene: 116622016

Centisome position: 36.95

GC content: 60.57

Gene sequence:

>2328_bases
ATGAACCGGACACAAGGAGAACCCATGGAGAAGATCAATCTCGGTCGGCGTTCGATACTCCGGGCTACTGCCTTAGCTGG
CGGCGGTATGATGCTTGGACTGTTTTCCCGGAATGCACGGGCACAGGCGCCGGCACAAGGGCCCGGCCGCGGCGCTCCTC
CTGCGCCGGGGGGCGGGCGTGGCGGCTTTGTCCGGACACCGCTGTCACCAGCCAATTTCGTCAGCATTTCGCCTGACGGC
ATCGCCTCGATAGGTTCGCCAAACACGGAGATGGGGCAGGGCTCGTTCAATCTGCTGCCGATGATGGTGGCTGAAGAGTT
GGACATCGATTGGAAGAACGTCAAAATCGTGCGCACCGGAGTGGGGCCGCAATTTGGCGGTCAGTTCACCGCCGGTAGCA
CCGCGACTCCCTCGAACTGGGTGCCGATGCGTCAAATCGGCGGCGCGGTACGAAGTATGCTCATCGCCGCTGCGGCACAG
AACTGGGGCGTCCCGGCGGCCGAATGTTCCACCACACCGGGCCGTGTGGTTCACACCGACTCAAACCGGTCGGCGGGTTA
CGGAGAACTTGCGGCGAAGGCCGCAACCATGCCCGTGCCGGACTTCAGCACGCTCAAGTTCAAAGACGCGAAGGACTACA
AAATCATCGGCACCACAACGCTCGGCGGGGAAACGAAAGACATCATCCGGGGCAAGGCTACGTTTGGCATCGACATCACC
GTCCCCGGAATGCTGTATGCGGTCTTCGAAAAGACCCCCGTGTCCCGCGGCAAAGTGGTCAGTGCGAACCTCGACGCCGT
CAAGGCGATGAAGGGCGTGAAGCACGCCTTCATCGTGGAAGGCGCACCCGTTAACGGGAATTATCCGAATTACCTATTTG
CCGATCCGGGGCTCGAGGCCGGCGTTGCGATTGTCGCGGAAAGCTGGTGGGCCGCGCAATCGGCGCGGAAGAAATTACAG
GTGAAATGGGATCTCGGCCCGTGGGCGTTGCAGGACAGCGATCAGACTGCTGCCAAAGCAGAGGAACTGTCCAAACAAGC
GCCGGCACGGACCCTTCGGAAGGACGGAGACACGGATGCGGTATTTCAGCGAACTGACGTCCGCGTGATCCAGAGCGCAT
ACCGCTTCCCGTTCATCGCTCATAACACGCTCGAACCTCAGAACGCCACGGCGCATTACCGCAATGGCAAGGTGGAAGTC
TGGTCCACCAGTCAGTTGCCCCAGACGGGGCGCCAGTTGGTGGCCCGAACCTTAGGCATTCCCGAAGCCGATGTAACCGT
CCACATGGTGCGCGCCGGTGGCGGCTTCGGACGCCGCTGCTATAACGACACCATGGCGGAAGCCGCCTGGATTTCCAAAA
CGGTCGGGGCGCCCGTCAAGTTGCTGTGGACTCGTGAAGACGACCTGCAGCACGACTATTATCGCCCGGGCGGATTTCAG
TACCTGAAAGCCGCGATCGACCAGAACGGCAAGCTCGCTGCATGGCACGATCATTTTATTAGTTACGGTGAAGGGAATAC
GTTTATTTCGGAGGGCGGATTCGATGCTGGTCAGTTTCCGGCAGGGTTGATCCGCGACTATCAGGTGCAGGCGTCGGTAT
TGCCTCTGGTTTTGAAAACCGGCGCATTGCGCGCACCAGGATCCAACTGCAGCGCGTGGGTTGTTCAGTCTTTCCTCGAT
GATGTCGCACACGCCGCAGGCAAAGATCCGCTGGCGTTACGGCTGGAATTGCTTGCATCGGCGCCACCACCCGCAGCGCC
TGCCCCAGGGCCGGGAGGCGGGCCTCCCGGTGGAGGCAGACAGGGCATGAACCCGGCTCGGATGCGAGCGGTACTCGAGC
TTGTAGCGGAAAAGTCCGGTTGGGGCAAGCGCCAGTTGCCGCCGCGGACGGCGCTCGGCATCGCGAGCCATTTCAGCGCC
GGCGGCTACGTTGCGGAGGTGGCCGAAGTCACCGTAAGTGCCGACAAGAAAATCAAGGTCAACAGGGTCTGGGTAGCGGC
TGATGTCGGCAGTCAAATTGTCAATCCGGGCGCCGCGGAGCATGTGGTGCAAGGCGCCGTCATCGACGGGATGAGCGAAC
TGATCCAGGAGATCACTCTGAAGAACGGCCGGGTGGTGCAATCGAACTTTCATCAGCATTCGGTATTGGATCTGCCTCAG
GCACCCCAGATTGACGTACACTTCCTGAAATCGAACAACTCACCAGGCGGATTAGGCGAACCCCCGTTGCCCCCGATTCT
CCCCGCTGTATGCAACGCGATTTTTAAGGCCACAGGAGAGCGCATCCACACTTTACCCATGACGAAACAGGGCTACCGCT
TTGCCTAA

Upstream 100 bases:

>100_bases
CGGCCATGGCAGGTAACATCTGCCGTTGCGGAACGTATGGGCGGCTTCGCGCTGCAATCCACAAAGCATCGGATGCGATG
AAATCAGGAGCGACGAAGCG

Downstream 100 bases:

>100_bases
ATTACCCTGAAGGGCACCTGAATGGATATATTCGAGGAATTAGTCCGGCTCCGCAATCTGGGACAGAAATGCGCACTTGC
CACCATAGTGGAAGTGCGCG

Product: aldehyde oxidase and xanthine dehydrogenase molybdopterin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 775; Mature: 775

Protein sequence:

>775_residues
MNRTQGEPMEKINLGRRSILRATALAGGGMMLGLFSRNARAQAPAQGPGRGAPPAPGGGRGGFVRTPLSPANFVSISPDG
IASIGSPNTEMGQGSFNLLPMMVAEELDIDWKNVKIVRTGVGPQFGGQFTAGSTATPSNWVPMRQIGGAVRSMLIAAAAQ
NWGVPAAECSTTPGRVVHTDSNRSAGYGELAAKAATMPVPDFSTLKFKDAKDYKIIGTTTLGGETKDIIRGKATFGIDIT
VPGMLYAVFEKTPVSRGKVVSANLDAVKAMKGVKHAFIVEGAPVNGNYPNYLFADPGLEAGVAIVAESWWAAQSARKKLQ
VKWDLGPWALQDSDQTAAKAEELSKQAPARTLRKDGDTDAVFQRTDVRVIQSAYRFPFIAHNTLEPQNATAHYRNGKVEV
WSTSQLPQTGRQLVARTLGIPEADVTVHMVRAGGGFGRRCYNDTMAEAAWISKTVGAPVKLLWTREDDLQHDYYRPGGFQ
YLKAAIDQNGKLAAWHDHFISYGEGNTFISEGGFDAGQFPAGLIRDYQVQASVLPLVLKTGALRAPGSNCSAWVVQSFLD
DVAHAAGKDPLALRLELLASAPPPAAPAPGPGGGPPGGGRQGMNPARMRAVLELVAEKSGWGKRQLPPRTALGIASHFSA
GGYVAEVAEVTVSADKKIKVNRVWVAADVGSQIVNPGAAEHVVQGAVIDGMSELIQEITLKNGRVVQSNFHQHSVLDLPQ
APQIDVHFLKSNNSPGGLGEPPLPPILPAVCNAIFKATGERIHTLPMTKQGYRFA

Sequences:

>Translated_775_residues
MNRTQGEPMEKINLGRRSILRATALAGGGMMLGLFSRNARAQAPAQGPGRGAPPAPGGGRGGFVRTPLSPANFVSISPDG
IASIGSPNTEMGQGSFNLLPMMVAEELDIDWKNVKIVRTGVGPQFGGQFTAGSTATPSNWVPMRQIGGAVRSMLIAAAAQ
NWGVPAAECSTTPGRVVHTDSNRSAGYGELAAKAATMPVPDFSTLKFKDAKDYKIIGTTTLGGETKDIIRGKATFGIDIT
VPGMLYAVFEKTPVSRGKVVSANLDAVKAMKGVKHAFIVEGAPVNGNYPNYLFADPGLEAGVAIVAESWWAAQSARKKLQ
VKWDLGPWALQDSDQTAAKAEELSKQAPARTLRKDGDTDAVFQRTDVRVIQSAYRFPFIAHNTLEPQNATAHYRNGKVEV
WSTSQLPQTGRQLVARTLGIPEADVTVHMVRAGGGFGRRCYNDTMAEAAWISKTVGAPVKLLWTREDDLQHDYYRPGGFQ
YLKAAIDQNGKLAAWHDHFISYGEGNTFISEGGFDAGQFPAGLIRDYQVQASVLPLVLKTGALRAPGSNCSAWVVQSFLD
DVAHAAGKDPLALRLELLASAPPPAAPAPGPGGGPPGGGRQGMNPARMRAVLELVAEKSGWGKRQLPPRTALGIASHFSA
GGYVAEVAEVTVSADKKIKVNRVWVAADVGSQIVNPGAAEHVVQGAVIDGMSELIQEITLKNGRVVQSNFHQHSVLDLPQ
APQIDVHFLKSNNSPGGLGEPPLPPILPAVCNAIFKATGERIHTLPMTKQGYRFA
>Mature_775_residues
MNRTQGEPMEKINLGRRSILRATALAGGGMMLGLFSRNARAQAPAQGPGRGAPPAPGGGRGGFVRTPLSPANFVSISPDG
IASIGSPNTEMGQGSFNLLPMMVAEELDIDWKNVKIVRTGVGPQFGGQFTAGSTATPSNWVPMRQIGGAVRSMLIAAAAQ
NWGVPAAECSTTPGRVVHTDSNRSAGYGELAAKAATMPVPDFSTLKFKDAKDYKIIGTTTLGGETKDIIRGKATFGIDIT
VPGMLYAVFEKTPVSRGKVVSANLDAVKAMKGVKHAFIVEGAPVNGNYPNYLFADPGLEAGVAIVAESWWAAQSARKKLQ
VKWDLGPWALQDSDQTAAKAEELSKQAPARTLRKDGDTDAVFQRTDVRVIQSAYRFPFIAHNTLEPQNATAHYRNGKVEV
WSTSQLPQTGRQLVARTLGIPEADVTVHMVRAGGGFGRRCYNDTMAEAAWISKTVGAPVKLLWTREDDLQHDYYRPGGFQ
YLKAAIDQNGKLAAWHDHFISYGEGNTFISEGGFDAGQFPAGLIRDYQVQASVLPLVLKTGALRAPGSNCSAWVVQSFLD
DVAHAAGKDPLALRLELLASAPPPAAPAPGPGGGPPGGGRQGMNPARMRAVLELVAEKSGWGKRQLPPRTALGIASHFSA
GGYVAEVAEVTVSADKKIKVNRVWVAADVGSQIVNPGAAEHVVQGAVIDGMSELIQEITLKNGRVVQSNFHQHSVLDLPQ
APQIDVHFLKSNNSPGGLGEPPLPPILPAVCNAIFKATGERIHTLPMTKQGYRFA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=383, Percent_Identity=25.3263707571802, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786478, Length=426, Percent_Identity=24.6478873239437, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 82308; Mature: 82308

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTQGEPMEKINLGRRSILRATALAGGGMMLGLFSRNARAQAPAQGPGRGAPPAPGGGR
CCCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GGFVRTPLSPANFVSISPDGIASIGSPNTEMGQGSFNLLPMMVAEELDIDWKNVKIVRTG
CCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEC
VGPQFGGQFTAGSTATPSNWVPMRQIGGAVRSMLIAAAAQNWGVPAAECSTTPGRVVHTD
CCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEECC
SNRSAGYGELAAKAATMPVPDFSTLKFKDAKDYKIIGTTTLGGETKDIIRGKATFGIDIT
CCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCEEEEEEEECCCCCHHHHCCCEEEEEEEE
VPGMLYAVFEKTPVSRGKVVSANLDAVKAMKGVKHAFIVEGAPVNGNYPNYLFADPGLEA
CCHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCC
GVAIVAESWWAAQSARKKLQVKWDLGPWALQDSDQTAAKAEELSKQAPARTLRKDGDTDA
CEEEEEHHHHHHHHHCCEEEEEECCCCCEECCCCHHHHHHHHHHHHCCHHHHHCCCCCHH
VFQRTDVRVIQSAYRFPFIAHNTLEPQNATAHYRNGKVEVWSTSQLPQTGRQLVARTLGI
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCC
PEADVTVHMVRAGGGFGRRCYNDTMAEAAWISKTVGAPVKLLWTREDDLQHDYYRPGGFQ
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHH
YLKAAIDQNGKLAAWHDHFISYGEGNTFISEGGFDAGQFPAGLIRDYQVQASVLPLVLKT
HHHHHHCCCCCEEEEEHHHEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GALRAPGSNCSAWVVQSFLDDVAHAAGKDPLALRLELLASAPPPAAPAPGPGGGPPGGGR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
QGMNPARMRAVLELVAEKSGWGKRQLPPRTALGIASHFSAGGYVAEVAEVTVSADKKIKV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEE
NRVWVAADVGSQIVNPGAAEHVVQGAVIDGMSELIQEITLKNGRVVQSNFHQHSVLDLPQ
EEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
APQIDVHFLKSNNSPGGLGEPPLPPILPAVCNAIFKATGERIHTLPMTKQGYRFA
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MNRTQGEPMEKINLGRRSILRATALAGGGMMLGLFSRNARAQAPAQGPGRGAPPAPGGGR
CCCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GGFVRTPLSPANFVSISPDGIASIGSPNTEMGQGSFNLLPMMVAEELDIDWKNVKIVRTG
CCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEC
VGPQFGGQFTAGSTATPSNWVPMRQIGGAVRSMLIAAAAQNWGVPAAECSTTPGRVVHTD
CCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEECC
SNRSAGYGELAAKAATMPVPDFSTLKFKDAKDYKIIGTTTLGGETKDIIRGKATFGIDIT
CCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCEEEEEEEECCCCCHHHHCCCEEEEEEEE
VPGMLYAVFEKTPVSRGKVVSANLDAVKAMKGVKHAFIVEGAPVNGNYPNYLFADPGLEA
CCHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCC
GVAIVAESWWAAQSARKKLQVKWDLGPWALQDSDQTAAKAEELSKQAPARTLRKDGDTDA
CEEEEEHHHHHHHHHCCEEEEEECCCCCEECCCCHHHHHHHHHHHHCCHHHHHCCCCCHH
VFQRTDVRVIQSAYRFPFIAHNTLEPQNATAHYRNGKVEVWSTSQLPQTGRQLVARTLGI
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCC
PEADVTVHMVRAGGGFGRRCYNDTMAEAAWISKTVGAPVKLLWTREDDLQHDYYRPGGFQ
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHH
YLKAAIDQNGKLAAWHDHFISYGEGNTFISEGGFDAGQFPAGLIRDYQVQASVLPLVLKT
HHHHHHCCCCCEEEEEHHHEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GALRAPGSNCSAWVVQSFLDDVAHAAGKDPLALRLELLASAPPPAAPAPGPGGGPPGGGR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
QGMNPARMRAVLELVAEKSGWGKRQLPPRTALGIASHFSAGGYVAEVAEVTVSADKKIKV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEE
NRVWVAADVGSQIVNPGAAEHVVQGAVIDGMSELIQEITLKNGRVVQSNFHQHSVLDLPQ
EEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
APQIDVHFLKSNNSPGGLGEPPLPPILPAVCNAIFKATGERIHTLPMTKQGYRFA
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]