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The map label for this gene is iorA [H]

Identifier: 116622018

GI number: 116622018

Start: 3681985

End: 3682458

Strand: Reverse

Name: iorA [H]

Synonym: Acid_2903

Alternate gene names: 116622018

Gene position: 3682458-3681985 (Counterclockwise)

Preceding gene: 116622019

Following gene: 116622017

Centisome position: 36.95

GC content: 58.23

Gene sequence:

>474_bases
ATGATCACGCTCAACATCAATGGAAAGCAGCAGAGGTTCGACGGCGATCCCGACATGCCGTTGCTTTGGGTGCTTCGAGA
TGAATTCAATCTGAAGGGCACCAAGTTCGGCTGCGGCATGGGATTGTGCGGCGCCTGCACGATCCATGTCAACGGAGAGC
CTGTCCGCTCTTGTGTCATGTCGGCGGCGAACGCAGCTGGCAAGAAGATCACCACCATCGAAGGCCTTTCGCCGGACGGC
TCGCATCCCGTGCAGGTTGCCTGGGAAGCACTCGACGTTCCACAGTGCGGTTACTGTCAGACGGGCCAGATCATGAGCGC
ATGCGCGCTGCTCACCAAGAAGAAGACTCCCAGGGACGCTGACATCGATTCGGCCATGGCAGGTAACATCTGCCGTTGCG
GAACGTATGGGCGGCTTCGCGCTGCAATCCACAAAGCATCGGATGCGATGAAATCAGGAGCGACGAAGCGATGA

Upstream 100 bases:

>100_bases
TGTTCCCGATCGCCCGGCAGTGCAGAATGGTGAGCACACGCGAGAGTCCTGCCCTTTTCCAACCACTTGGAATTTCGGGG
TGTCACCGCGGGAGGGTTTC

Downstream 100 bases:

>100_bases
ACCGGACACAAGGAGAACCCATGGAGAAGATCAATCTCGGTCGGCGTTCGATACTCCGGGCTACTGCCTTAGCTGGCGGC
GGTATGATGCTTGGACTGTT

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MITLNINGKQQRFDGDPDMPLLWVLRDEFNLKGTKFGCGMGLCGACTIHVNGEPVRSCVMSAANAAGKKITTIEGLSPDG
SHPVQVAWEALDVPQCGYCQTGQIMSACALLTKKKTPRDADIDSAMAGNICRCGTYGRLRAAIHKASDAMKSGATKR

Sequences:

>Translated_157_residues
MITLNINGKQQRFDGDPDMPLLWVLRDEFNLKGTKFGCGMGLCGACTIHVNGEPVRSCVMSAANAAGKKITTIEGLSPDG
SHPVQVAWEALDVPQCGYCQTGQIMSACALLTKKKTPRDADIDSAMAGNICRCGTYGRLRAAIHKASDAMKSGATKR
>Mature_157_residues
MITLNINGKQQRFDGDPDMPLLWVLRDEFNLKGTKFGCGMGLCGACTIHVNGEPVRSCVMSAANAAGKKITTIEGLSPDG
SHPVQVAWEALDVPQCGYCQTGQIMSACALLTKKKTPRDADIDSAMAGNICRCGTYGRLRAAIHKASDAMKSGATKR

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=42.5149700598802, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=40.8450704225352, Blast_Score=88, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=38.0645161290323, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=34.8387096774194, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=32.2784810126582, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=34.8993288590604, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24647197, Length=169, Percent_Identity=31.9526627218935, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647195, Length=169, Percent_Identity=31.9526627218935, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647201, Length=163, Percent_Identity=33.1288343558282, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24647193, Length=169, Percent_Identity=32.5443786982249, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24647199, Length=146, Percent_Identity=32.8767123287671, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16720; Mature: 16720

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
10.2 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
10.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLNINGKQQRFDGDPDMPLLWVLRDEFNLKGTKFGCGMGLCGACTIHVNGEPVRSCVM
CEEEECCCCHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHH
SAANAAGKKITTIEGLSPDGSHPVQVAWEALDVPQCGYCQTGQIMSACALLTKKKTPRDA
HHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DIDSAMAGNICRCGTYGRLRAAIHKASDAMKSGATKR
CCCHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MITLNINGKQQRFDGDPDMPLLWVLRDEFNLKGTKFGCGMGLCGACTIHVNGEPVRSCVM
CEEEECCCCHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHH
SAANAAGKKITTIEGLSPDGSHPVQVAWEALDVPQCGYCQTGQIMSACALLTKKKTPRDA
HHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DIDSAMAGNICRCGTYGRLRAAIHKASDAMKSGATKR
CCCHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]