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The map label for this gene is nodV [H]

Identifier: 116622000

GI number: 116622000

Start: 3657629

End: 3659302

Strand: Direct

Name: nodV [H]

Synonym: Acid_2885

Alternate gene names: 116622000

Gene position: 3657629-3659302 (Clockwise)

Preceding gene: 116621999

Following gene: 116622003

Centisome position: 36.7

GC content: 62.96

Gene sequence:

>1674_bases
GTGAGCGGGATCAGTACCATTCTGGTGGTGGACGACGACTCGGATTCGCTGCGGTTGTTGACCGATATTTTGACGGCGGA
AGGATATCGGGTACGCCCCGCGGATAGCGGTCAACTGGCGCTGGCGTCGGCAAAGGCAGCGGCTCCGGAGTTGATCATGC
TGGATATCCGGATGCCCGGGATGGACGGGTTCGAGGTCTGCCGGCGGCTGCAGGCGGACGAAAAGACGCGGAGGATTCCG
ATCATCTTCCTGAGCGCGGCCGGACAGCTTCAGGATCGCGTGCTGGGGCTGAGCCTGGGCGCTGCGGATTTTATTTCCAA
GCCGTATGAGCGGCCGGAGTTGCTGGCGCGGGTTCGGACCCACATGGAACTGGGGCGGTTGCGCGCTCACCTGGAACATC
AAGTGGCGGCGCAAACGGCGGAACTGCGCCTGGCCAATGAGCAATTGTCGCTGGAACTGGAAGAGCGTCTGCGCGCAGAG
CAGGAACTGCGCGAAAGCGAGGCACGGTTCCGCAGTCTCGCCGACCGGGCGCCGGTGGGGATCTGGCTGACAACGCTGGA
TAACGAGGTCACGTTTTACAACCGGCGCGCACTGGCATTCCTGGGGCGAAAGGCGGCGGAGAGGAGCGGACTGAGCTGGG
CGGAGTTTGTGCACCCTGAGGATATGGACGCGGTTAAGGCGAAGTACCAGGCTGCTGTCAGCGCGCGCCGAAGTTTTCGA
ATCGAGTGCCGCGTACGGCGGTGGAACGGAAAATATCGCTGGGTGTTGAACACGGGGATTCCGCGGATGATCGATGGTGT
GTGCACCGGGTACATCACGACCAGCACCGACATCACGGACCTGAAGCGGCGGCAGGAAGAACTGCTGATGCACCAGAAGC
TGGAGAGCCTTGGCGTGCTGGCCGGCGGCGTAGCTCACGATTTCAATAACCTGTTGGGCAGCATTCTGGCGGAATCGGAC
CTGGCGATGTCGGACCTGCCGGAGGATACGCCGGGGCGGGACGGCGTAGAGCGAATTGCGGCGATCGCGCAGCGGGCATC
GGAGATCGTGAACCTGCTGATGACCTACGCGGGGGATCGCGACCTGGCGATCGAGGGCGTGGATCTGTCCAAGGTGACAT
CGGAAGTGCTGTTTCTGATGAGGCCGCCGCTGAGCGAGACGGCGGTGATCGAGCTGAACCTGGTGAAGGATTTGCCGCTG
GTGCAGGCAAACAAAGCGCAGATCCGGCAGGTGGTGATGAATCTGCTCACGAATGCCGCCGAGGCGCTGAAGGGCAGGGG
CGGGAAGATCACGGTAAGTACGGGGTTGGTGCACATCGGGAAAGCGGCGGCGGCAAAGCGCAAGCTCAATCTGCCGGTGG
GCGAGTATTGTTTCCTTTCGGTTTCGGACACGGGATGCGGCATGTCGCCGCAGACGAAAGACAAGGTCTTCGACCCGTTT
TACAGCACCAAGTTCGTTGGGCGAGGCTTGGGCCTGGCGGCGGTGCAGGGGATTTTACGATCGCACCGGGGCGCGATCAG
CGTGGTGAGCGAGCCGGAGCGGGGATCCACGTTCGAGGTGCTGCTGCCGCGATCCGGGAAGCGCGAGCGGCACCGGAGAG
AATCGATGCCCGAGCACGATACTCCGCTGGTTTCGACGGCATCGGGTGGCTCGGGAACTCGCGGGTGGCACTGA

Upstream 100 bases:

>100_bases
CATTGGGCTCGGCGATGGCGGGACTGGCGGAGCGGCTGGCCTACACGTCTATCCTGCAGGCGATCGCGGTTCGGAAGTCG
AGCGCTCTAGAGGGACAAGC

Downstream 100 bases:

>100_bases
CGCGATGTTTCCGAAGGGCGGCCGGGGGGAGCCGGCTGCACGGTCGAAAAGCTCACGTGGAGCAAGGAAATACTCCTCGA
AAAAGTGCGGCGTAGCTGAC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MSGISTILVVDDDSDSLRLLTDILTAEGYRVRPADSGQLALASAKAAAPELIMLDIRMPGMDGFEVCRRLQADEKTRRIP
IIFLSAAGQLQDRVLGLSLGAADFISKPYERPELLARVRTHMELGRLRAHLEHQVAAQTAELRLANEQLSLELEERLRAE
QELRESEARFRSLADRAPVGIWLTTLDNEVTFYNRRALAFLGRKAAERSGLSWAEFVHPEDMDAVKAKYQAAVSARRSFR
IECRVRRWNGKYRWVLNTGIPRMIDGVCTGYITTSTDITDLKRRQEELLMHQKLESLGVLAGGVAHDFNNLLGSILAESD
LAMSDLPEDTPGRDGVERIAAIAQRASEIVNLLMTYAGDRDLAIEGVDLSKVTSEVLFLMRPPLSETAVIELNLVKDLPL
VQANKAQIRQVVMNLLTNAAEALKGRGGKITVSTGLVHIGKAAAAKRKLNLPVGEYCFLSVSDTGCGMSPQTKDKVFDPF
YSTKFVGRGLGLAAVQGILRSHRGAISVVSEPERGSTFEVLLPRSGKRERHRRESMPEHDTPLVSTASGGSGTRGWH

Sequences:

>Translated_557_residues
MSGISTILVVDDDSDSLRLLTDILTAEGYRVRPADSGQLALASAKAAAPELIMLDIRMPGMDGFEVCRRLQADEKTRRIP
IIFLSAAGQLQDRVLGLSLGAADFISKPYERPELLARVRTHMELGRLRAHLEHQVAAQTAELRLANEQLSLELEERLRAE
QELRESEARFRSLADRAPVGIWLTTLDNEVTFYNRRALAFLGRKAAERSGLSWAEFVHPEDMDAVKAKYQAAVSARRSFR
IECRVRRWNGKYRWVLNTGIPRMIDGVCTGYITTSTDITDLKRRQEELLMHQKLESLGVLAGGVAHDFNNLLGSILAESD
LAMSDLPEDTPGRDGVERIAAIAQRASEIVNLLMTYAGDRDLAIEGVDLSKVTSEVLFLMRPPLSETAVIELNLVKDLPL
VQANKAQIRQVVMNLLTNAAEALKGRGGKITVSTGLVHIGKAAAAKRKLNLPVGEYCFLSVSDTGCGMSPQTKDKVFDPF
YSTKFVGRGLGLAAVQGILRSHRGAISVVSEPERGSTFEVLLPRSGKRERHRRESMPEHDTPLVSTASGGSGTRGWH
>Mature_556_residues
SGISTILVVDDDSDSLRLLTDILTAEGYRVRPADSGQLALASAKAAAPELIMLDIRMPGMDGFEVCRRLQADEKTRRIPI
IFLSAAGQLQDRVLGLSLGAADFISKPYERPELLARVRTHMELGRLRAHLEHQVAAQTAELRLANEQLSLELEERLRAEQ
ELRESEARFRSLADRAPVGIWLTTLDNEVTFYNRRALAFLGRKAAERSGLSWAEFVHPEDMDAVKAKYQAAVSARRSFRI
ECRVRRWNGKYRWVLNTGIPRMIDGVCTGYITTSTDITDLKRRQEELLMHQKLESLGVLAGGVAHDFNNLLGSILAESDL
AMSDLPEDTPGRDGVERIAAIAQRASEIVNLLMTYAGDRDLAIEGVDLSKVTSEVLFLMRPPLSETAVIELNLVKDLPLV
QANKAQIRQVVMNLLTNAAEALKGRGGKITVSTGLVHIGKAAAAKRKLNLPVGEYCFLSVSDTGCGMSPQTKDKVFDPFY
STKFVGRGLGLAAVQGILRSHRGAISVVSEPERGSTFEVLLPRSGKRERHRRESMPEHDTPLVSTASGGSGTRGWH

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=31.1740890688259, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=28.1853281853282, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=40.7079646017699, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788394, Length=130, Percent_Identity=36.1538461538462, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=30.0751879699248, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=39.4957983193277, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790860, Length=115, Percent_Identity=36.5217391304348, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=35.3448275862069, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082012, Length=138, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786911, Length=174, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=270, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI2367329, Length=116, Percent_Identity=39.6551724137931, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=27.1966527196653, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790552, Length=113, Percent_Identity=33.6283185840708, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI145693157, Length=291, Percent_Identity=26.4604810996564, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=112, Percent_Identity=33.9285714285714, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790863, Length=114, Percent_Identity=32.4561403508772, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=33.6363636363636, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI48994928, Length=440, Percent_Identity=22.2727272727273, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61369; Mature: 61238

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGISTILVVDDDSDSLRLLTDILTAEGYRVRPADSGQLALASAKAAAPELIMLDIRMPG
CCCCEEEEEEECCCCHHHHHHHHHHCCCCEECCCCCCCEEEEEHHCCCCCEEEEEEECCC
MDGFEVCRRLQADEKTRRIPIIFLSAAGQLQDRVLGLSLGAADFISKPYERPELLARVRT
CCHHHHHHHHHCCHHHCCCCEEEEECCCCHHHHHHHEECCHHHHHHCCCCCHHHHHHHHH
HMELGRLRAHLEHQVAAQTAELRLANEQLSLELEERLRAEQELRESEARFRSLADRAPVG
HHHHHHHHHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IWLTTLDNEVTFYNRRALAFLGRKAAERSGLSWAEFVHPEDMDAVKAKYQAAVSARRSFR
EEEEEECCCEEEECCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCEE
IECRVRRWNGKYRWVLNTGIPRMIDGVCTGYITTSTDITDLKRRQEELLMHQKLESLGVL
EEEEEEEECCEEEEEEECCCHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AGGVAHDFNNLLGSILAESDLAMSDLPEDTPGRDGVERIAAIAQRASEIVNLLMTYAGDR
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLAIEGVDLSKVTSEVLFLMRPPLSETAVIELNLVKDLPLVQANKAQIRQVVMNLLTNAA
CEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EALKGRGGKITVSTGLVHIGKAAAAKRKLNLPVGEYCFLSVSDTGCGMSPQTKDKVFDPF
HHHHCCCCEEEEECCCEECCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHCCCH
YSTKFVGRGLGLAAVQGILRSHRGAISVVSEPERGSTFEVLLPRSGKRERHRRESMPEHD
HHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHCCCCCC
TPLVSTASGGSGTRGWH
CCEEEECCCCCCCCCCC
>Mature Secondary Structure 
SGISTILVVDDDSDSLRLLTDILTAEGYRVRPADSGQLALASAKAAAPELIMLDIRMPG
CCCEEEEEEECCCCHHHHHHHHHHCCCCEECCCCCCCEEEEEHHCCCCCEEEEEEECCC
MDGFEVCRRLQADEKTRRIPIIFLSAAGQLQDRVLGLSLGAADFISKPYERPELLARVRT
CCHHHHHHHHHCCHHHCCCCEEEEECCCCHHHHHHHEECCHHHHHHCCCCCHHHHHHHHH
HMELGRLRAHLEHQVAAQTAELRLANEQLSLELEERLRAEQELRESEARFRSLADRAPVG
HHHHHHHHHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IWLTTLDNEVTFYNRRALAFLGRKAAERSGLSWAEFVHPEDMDAVKAKYQAAVSARRSFR
EEEEEECCCEEEECCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCEE
IECRVRRWNGKYRWVLNTGIPRMIDGVCTGYITTSTDITDLKRRQEELLMHQKLESLGVL
EEEEEEEECCEEEEEEECCCHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AGGVAHDFNNLLGSILAESDLAMSDLPEDTPGRDGVERIAAIAQRASEIVNLLMTYAGDR
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLAIEGVDLSKVTSEVLFLMRPPLSETAVIELNLVKDLPLVQANKAQIRQVVMNLLTNAA
CEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EALKGRGGKITVSTGLVHIGKAAAAKRKLNLPVGEYCFLSVSDTGCGMSPQTKDKVFDPF
HHHHCCCCEEEEECCCEECCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHCCCH
YSTKFVGRGLGLAAVQGILRSHRGAISVVSEPERGSTFEVLLPRSGKRERHRRESMPEHD
HHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHCCCCCC
TPLVSTASGGSGTRGWH
CCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]