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The map label for this gene is gki [H]

Identifier: 116517028

GI number: 116517028

Start: 607682

End: 608641

Strand: Direct

Name: gki [H]

Synonym: SPD_0580

Alternate gene names: 116517028

Gene position: 607682-608641 (Clockwise)

Preceding gene: 116516626

Following gene: 116516193

Centisome position: 29.7

GC content: 44.38

Gene sequence:

>960_bases
ATGAGTCAAAAGATTATTGGGATTGACCTTGGTGGAACTTCTATCAAATTTGCAATCTTAACAACAGCAGGAGAAATCCA
AGGAAAATGGTCAATCAAGACCAACATTTTGGATGAGGGAAGTCATATCGTTGATGATATGATTGAGTCTATTCAACATC
GTTTGGACTTGCTTGGATTGGCAGCAGCGGACTTCCAAGGCATTGGAATGGGATCACCAGGTGTGGTTGACCGTGACAAA
GGGACTGTTATCGGTGCCTACAACTTGAACTGGAAAACCCTTCAACCAATCAAACAAAAGATTGAAAAAGCTTTGGGCAT
TCCATTTTTCATCGATAATGATGCCAACGTAGCAGCTCTTGGTGAGCGCTGGATGGGTGCTGGAGATAACCAACCAGACG
TTGTCTTTATGACACTCGGTACTGGTGTTGGTGGCGGTATCGTCGCAGAAGGCAAATTGCTTCACGGTGTTGCTGGTGCA
GCAGGTGAGCTTGGTCACATCACTGTTGACTTTGACCAGCCAATCTCATGTACTTGTGGTAAAAAAGGCTGCCTTGAGAC
AGTTGCTTCAGCAACAGGGATTGTCAACTTGACTCGTCGCTATGCCGATGAATACGAAGGCGATGCAGCCTTGAAACGCT
TGATTGATAACGGAGAAGAAGTAACTGCTAAGACTGTCTTTGATCTCGCAAAAGAAGGAGACGACCTTGCTTTGATTGTT
TACCGTAACTTCTCACGTTACTTGGGAATCGCTTGTGCTAACATTGGTTCAATCCTAAACCCATCAACAATCGTCATCGG
TGGTGGTGTGTCAGCTGCGGGAGAATTCCTTCTACAAGGTGTTCAAAAAGTTTACGATGAAAATAGTTTCCCACAAGTAC
GCACATCTACTAAATTAGCTCTTGCAACTCTAGGAAATGACGCTGGAGTTATCGGAGCAGCATCACTTGTATTGCAATAA

Upstream 100 bases:

>100_bases
TTATAATTCACTTACGCAAACCTTTGCATAAGTGAATGAATTTTGATATACTAGTACTGTAAGCATTTTCAATTACTACA
CAATGAAAAAGGAGAATATG

Downstream 100 bases:

>100_bases
GATAATGAGAGAGGAAAATGCTAACCTAGAGTTAGTAATGTTCCTCTTTTATTTTTTATGCTATACTAGTTAGGACAATG
AATGAGGTGAAACGAAATGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDK
GTVIGAYNLNWKTLQPIKQKIEKALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ

Sequences:

>Translated_319_residues
MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDK
GTVIGAYNLNWKTLQPIKQKIEKALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ
>Mature_318_residues
SQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKG
TVIGAYNLNWKTLQPIKQKIEKALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAA
GELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIVY
RNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI298566325, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI190014632, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4885285, Length=275, Percent_Identity=30.5454545454545, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI87081733, Length=322, Percent_Identity=31.055900621118, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787363, Length=321, Percent_Identity=27.1028037383178, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786891, Length=283, Percent_Identity=27.9151943462898, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787878, Length=250, Percent_Identity=25.6, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790522, Length=323, Percent_Identity=27.8637770897833, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082230, Length=272, Percent_Identity=29.7794117647059, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082127, Length=234, Percent_Identity=25.2136752136752, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33424; Mature: 33292

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGL
CCCEEEEEEECCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIEKALGIPFFIDNDANVAAL
HHHCCCCCCCCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCEEEH
GERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAAGELGHITVDFDQPISCTCG
HHHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEECCCCCEECCC
KKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENSFPQVRTSTKLA
EECCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LATLGNDAGVIGAASLVLQ
EEECCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIVDDMIESIQHRLDLLGL
CCEEEEEEECCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIEKALGIPFFIDNDANVAAL
HHHCCCCCCCCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCEEEH
GERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAAGELGHITVDFDQPISCTCG
HHHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEECCCCCEECCC
KKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNGEEVTAKTVFDLAKEGDDLALIV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
YRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENSFPQVRTSTKLA
EECCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LATLGNDAGVIGAASLVLQ
EEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]