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The map label for this gene is lytB [H]

Identifier: 116516626

GI number: 116516626

Start: 606557

End: 607546

Strand: Direct

Name: lytB [H]

Synonym: SPD_0579

Alternate gene names: 116516626

Gene position: 606557-607546 (Clockwise)

Preceding gene: 116516803

Following gene: 116517028

Centisome position: 29.64

GC content: 38.38

Gene sequence:

>990_bases
ATGAATAAACGTCTATTTTTAAAAATGAGTCTGGTGACGTTGCCAATTTTAGCCTTGTTTTCACAACCAGTTTTGGCGGA
AGAAAACATCCATTTTTCGAGCTGTAAGGAAGCTTGGGCGAATGGCTATTCGGATATTCACGAGGGGGAACCTGGTTATT
CTGCCAAGTTAGACCGTGATCATGATGGTGTGGCTTGCGAATTGAAAAATGCTCCTAAGGGTGCTTTTAAAGCAAAACAG
TCAACGGCTATTCAAATCAACACAAGTTCAGCAACAACAAGTGGTTGGGTTAAGCAGGACGGCGCTTGGTACTACTTTGA
TGGAAATGGAAATCTAGTGAAAAATGCATGGCAGGGAAGCTATTACCTGAAAGCTGATGGTAAAATGGCACAGAGTGAAT
GGATTTATGACTCTTCTTATCAAGCTTGGTATTATTTGAAATCAGATGGTTCTTATGCAAAAAATGCATGGCAAGGAGCT
TATTACCTTAAATCAAACGGTAAAATGGCACAAGGTGAGTGGGTTTATGATTCTTCTTACCAAGCATGGTATTACTTGAA
ATCAGATGGTTCATATGCTCGCAATGCATGGCAAGGAAACTACTATTTGAAATCAGATGGTAAAATGGCTAAAGGTGAAT
GGGTTTATGATGCCACCTATCAAGCTTGGTATTATTTGACATCAGATGGTTCTTATGCTTACAGTACATGGCAAGGAAAT
TACTATCTAAAATCGGATGGTAAAATGGCTGTCAATGAATGGGTTGATGGTGGACGTTATTATGTTGGCGCTGACGGAGT
TTGGAAGGAAGGTCAAGCAAGTACAGCTTCTTCTAGTAATGATAGCAATAGTGAATATTCTGCTGCTTTAGGAAAGGCAA
AAAGTTATAATTCGTTATTCCACATGTCAAAAAAACGTATGTATAGACAATTAACTTCTGATTTTGATAAATTTTCAAAT
GATGCAGCTCAATATGCCATTGATCATTAG

Upstream 100 bases:

>100_bases
CGGAATCAATTGAAGGATAAGCCCACAGAGACTCTTGAATTGCTGAAATAAGTTTGATAAAATAATATTGAAATCGATAT
CATAATTATGGGAGAAAGAA

Downstream 100 bases:

>100_bases
ATGATTAACAGATACTGGTAGGCGAAAAAAATTCCTTATAATTCACTTACGCAAACCTTTGCATAAGTGAATGAATTTTG
ATATACTAGTACTGTAAGCA

Product: pneumococcal surface protein

Products: NA

Alternate protein names: Murein hydrolase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYSDIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQ
STAIQINTSSATTSGWVKQDGAWYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDATYQAWYYLTSDGSYAYSTWQGN
YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSN
DAAQYAIDH

Sequences:

>Translated_329_residues
MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYSDIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQ
STAIQINTSSATTSGWVKQDGAWYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDATYQAWYYLTSDGSYAYSTWQGN
YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSN
DAAQYAIDH
>Mature_329_residues
MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYSDIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQ
STAIQINTSSATTSGWVKQDGAWYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDATYQAWYYLTSDGSYAYSTWQGN
YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSN
DAAQYAIDH

Specific function: Plays an important role in cell wall degradation and cell separation [H]

COG id: COG5263

COG function: function code R; FOG: Glucan-binding domain (YG repeat)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 15 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018337
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01473 CW_binding_1; PF01832 Glucosaminidase [H]

EC number: =3.2.1.96 [H]

Molecular weight: Translated: 37271; Mature: 37271

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYSDIHEGEPGYSAKLDRD
CCCEEEEEEHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCHHHCCCCCCCEECCCC
HDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGAWYYFDGNGNLVKNAWQGS
CCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEECCCEEEEECCCCCEEEEECCCE
YYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGAYYLKSNGKMAQGEWVYDSSY
EEEEECCCCCCCCEEECCCCEEEEEEECCCCCCHHCCCCEEEEECCCCEECCCEEEECCC
QAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDATYQAWYYLTSDGSYAYSTWQGN
EEEEEEECCCCHHHCEECCCEEECCCCCEECCCEEEEEEEEEEEEEECCCCEEEEEECCC
YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLF
EEECCCCCEEEEHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHH
HMSKKRMYRQLTSDFDKFSNDAAQYAIDH
HHHHHHHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYSDIHEGEPGYSAKLDRD
CCCEEEEEEHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCHHHCCCCCCCEECCCC
HDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGAWYYFDGNGNLVKNAWQGS
CCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEECCCEEEEECCCCCEEEEECCCE
YYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGAYYLKSNGKMAQGEWVYDSSY
EEEEECCCCCCCCEEECCCCEEEEEEECCCCCCHHCCCCEEEEECCCCEECCCEEEECCC
QAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDATYQAWYYLTSDGSYAYSTWQGN
EEEEEEECCCCHHHCEECCCEEECCCCCEECCCEEEEEEEEEEEEEECCCCEEEEEECCC
YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTASSSNDSNSEYSAALGKAKSYNSLF
EEECCCCCEEEEHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHH
HMSKKRMYRQLTSDFDKFSNDAAQYAIDH
HHHHHHHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10096093; 11544234 [H]