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The map label for this gene is pabB [H]

Identifier: 116516803

GI number: 116516803

Start: 604678

End: 606399

Strand: Direct

Name: pabB [H]

Synonym: SPD_0578

Alternate gene names: 116516803

Gene position: 604678-606399 (Clockwise)

Preceding gene: 116515780

Following gene: 116516626

Centisome position: 29.55

GC content: 43.09

Gene sequence:

>1722_bases
ATGCATAGAAAAACAGTGATTGATTTTAGGGCTTTGGGGGAGAGATACATCTTTACCAAGCCGATTAAAGAGTTGAAAAC
GAGAAATTTAACAGAAGTGGCAGATTTGCTGGCACAAGTGGAAAGCTATCAAGAGCAAGGCTATTATGTGGTGGGTTATG
TCAGCTACGAGGCTGCACCTGCTTTTGAGGAAAAATTAGCAGTTCATAAGGCTCCTCTACTGGGCGAGTACTTGCTTTAC
TTTACTGTTCATGATAGGGTAGAAACATCCCCTATTCCTCTGACTTATGATGAGGTTGATTTGCCTTCAAATTGGCAGGA
AGTAACGTCTGCAGCAGACTATGAAAAGGCTATTGCACAGATACATCATCATCTACGGCAGGGTGATACCTATCAGGTCA
ACTACACCGTCCAACTCAAACAAGATTTAAGCGCCAATCCTTTTGCTATCTACAATCGCATGGTGGTAGAGCAGGAGGCG
GGCTACAATGCCTATGTGGAACATGACGATATGGCAGTAATTTCCATGAGCCCAGAGCTCTTTTTTGAGCAAAATGACCG
CGAATTGACAACGCGACCAATGAAGGGAACGACTCAGCGTGCCATAACTGACCAAGAAGACTTGGAGCAGGCCAGTTGGT
TGGAACAGGATTCCAAAAATCGCTCTGAAAATATGATGATTGTGGACCTCTTGCGCAATGATATGAATCGTATTTCTGAG
GTGGGGAGTGAGCACGTGGAGCGTCTCTGCCAAGTGGAGCAGTATTCAACTGTTTGGCAGATGACTTCGACTATCAAGAG
TCAGTTACGAGCAGATGTTGATTTAGTTACAATTTTTCGCTCTCTCTTTCCTTGTGGATCTATAACGGGAGCTCCGAAAA
TTGCGACTATGGAGATTATCAAGGACTTGGAGCCACAACCGCGTGGAGTCTACTGTGGAACGATTGGTCTCTTGCATCCA
AATGGACGACGGATTTTTAATGTTGCTATCCGAACTATTCAACTGCATCAAGGGGAAGCCATCTATGGAGTTGGCGGAGG
TATTACATGGGATAGCACCTGGCAATCTGAATACCGCGAGGTTCATCAAAAGGCAGCTGTTCTCTATCGTAAACAAGCTC
GTTTCCAGCTGATTACTACTGGAAAAATCAGCCAGAAGAACTTGCTGTTTGAAGAACAACATTTGGAAAGACTGAGAACA
GCTAGTCGATATTTTGCCTTTCCTTATGATGCAGAAGACTTAAGACAAAAGATAGAGGCGGAGTGTCAGTCTTGTGACAT
TGATCAAGACTATCGCTTGCGAATTTCTCTCAGTAAGTCTGGAGAGATAGAACTTAGTCGACAAATCTTAACACCTCTTA
GTCTACATTTTTGTCAGGCCAAACTTTGTCTTCAGGAAGCCAATTTGCAACAAGCCTTTACCTATTTTAAAACGACTTAC
AGACCGCATTTAAACCTAGGGGAACAAGAGATTATTTACCACAATAAGTCAGGAGAACTGCTTGAAACCTCTATCGGAAA
TTTGGTTTTGAAAATTGCTGGGAAACTCTACACACCGCCTATCAGACTTGGTATCTTGCCAGGAATTTATCGCCAGTATT
TACTAGAAACAGGACAAGTAGAAGAGAAAGTCTTGACCTTGACAGATTTTGCCCAAGCAGAAGCTATTTATGGCTGTAAT
GCAGTGAGAGGCTTGTATGAATTAAGCCTAGAGGAAAATTAG

Upstream 100 bases:

>100_bases
TAGTGATCTATTTACTGCACCACAAGCATAGGGATGAATAAAATCGTAAAAAGGTAGATCAGCTTTGTCTGTATCTGCCT
TTTTATGCTATACTTAAGGT

Downstream 100 bases:

>100_bases
ATGAAACTGGTATTTTTACACGGTTTAGGGGAGTCAGCAGAGTCTTGGAAAGAAGTTCGGAATCAATTGAAGGATAAGCC
CACAGAGACTCTTGAATTGC

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MHRKTVIDFRALGERYIFTKPIKELKTRNLTEVADLLAQVESYQEQGYYVVGYVSYEAAPAFEEKLAVHKAPLLGEYLLY
FTVHDRVETSPIPLTYDEVDLPSNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQDLSANPFAIYNRMVVEQEA
GYNAYVEHDDMAVISMSPELFFEQNDRELTTRPMKGTTQRAITDQEDLEQASWLEQDSKNRSENMMIVDLLRNDMNRISE
VGSEHVERLCQVEQYSTVWQMTSTIKSQLRADVDLVTIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLHP
NGRRIFNVAIRTIQLHQGEAIYGVGGGITWDSTWQSEYREVHQKAAVLYRKQARFQLITTGKISQKNLLFEEQHLERLRT
ASRYFAFPYDAEDLRQKIEAECQSCDIDQDYRLRISLSKSGEIELSRQILTPLSLHFCQAKLCLQEANLQQAFTYFKTTY
RPHLNLGEQEIIYHNKSGELLETSIGNLVLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLTDFAQAEAIYGCN
AVRGLYELSLEEN

Sequences:

>Translated_573_residues
MHRKTVIDFRALGERYIFTKPIKELKTRNLTEVADLLAQVESYQEQGYYVVGYVSYEAAPAFEEKLAVHKAPLLGEYLLY
FTVHDRVETSPIPLTYDEVDLPSNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQDLSANPFAIYNRMVVEQEA
GYNAYVEHDDMAVISMSPELFFEQNDRELTTRPMKGTTQRAITDQEDLEQASWLEQDSKNRSENMMIVDLLRNDMNRISE
VGSEHVERLCQVEQYSTVWQMTSTIKSQLRADVDLVTIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLHP
NGRRIFNVAIRTIQLHQGEAIYGVGGGITWDSTWQSEYREVHQKAAVLYRKQARFQLITTGKISQKNLLFEEQHLERLRT
ASRYFAFPYDAEDLRQKIEAECQSCDIDQDYRLRISLSKSGEIELSRQILTPLSLHFCQAKLCLQEANLQQAFTYFKTTY
RPHLNLGEQEIIYHNKSGELLETSIGNLVLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLTDFAQAEAIYGCN
AVRGLYELSLEEN
>Mature_573_residues
MHRKTVIDFRALGERYIFTKPIKELKTRNLTEVADLLAQVESYQEQGYYVVGYVSYEAAPAFEEKLAVHKAPLLGEYLLY
FTVHDRVETSPIPLTYDEVDLPSNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQDLSANPFAIYNRMVVEQEA
GYNAYVEHDDMAVISMSPELFFEQNDRELTTRPMKGTTQRAITDQEDLEQASWLEQDSKNRSENMMIVDLLRNDMNRISE
VGSEHVERLCQVEQYSTVWQMTSTIKSQLRADVDLVTIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLHP
NGRRIFNVAIRTIQLHQGEAIYGVGGGITWDSTWQSEYREVHQKAAVLYRKQARFQLITTGKISQKNLLFEEQHLERLRT
ASRYFAFPYDAEDLRQKIEAECQSCDIDQDYRLRISLSKSGEIELSRQILTPLSLHFCQAKLCLQEANLQQAFTYFKTTY
RPHLNLGEQEIIYHNKSGELLETSIGNLVLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLTDFAQAEAIYGCN
AVRGLYELSLEEN

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=268, Percent_Identity=37.6865671641791, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787518, Length=292, Percent_Identity=29.1095890410959, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1786809, Length=244, Percent_Identity=22.9508196721311, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082077, Length=209, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=282, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=282, Percent_Identity=29.0780141843972, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 65820; Mature: 65820

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRKTVIDFRALGERYIFTKPIKELKTRNLTEVADLLAQVESYQEQGYYVVGYVSYEAAP
CCCCEEEHHHHCCCCCEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCC
AFEEKLAVHKAPLLGEYLLYFTVHDRVETSPIPLTYDEVDLPSNWQEVTSAADYEKAIAQ
HHHHHHHHHCCCHHHCEEEEEEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
IHHHLRQGDTYQVNYTVQLKQDLSANPFAIYNRMVVEQEAGYNAYVEHDDMAVISMSPEL
HHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHHHHEECCCCCCEEEECCCEEEEEECCHH
FFEQNDRELTTRPMKGTTQRAITDQEDLEQASWLEQDSKNRSENMMIVDLLRNDMNRISE
EEECCCCEEECCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
VGSEHVERLCQVEQYSTVWQMTSTIKSQLRADVDLVTIFRSLFPCGSITGAPKIATMEII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
KDLEPQPRGVYCGTIGLLHPNGRRIFNVAIRTIQLHQGEAIYGVGGGITWDSTWQSEYRE
HHCCCCCCEEEEEEEEEECCCCCEEEEEEEEEEEEECCCEEEECCCCCCCCCCHHHHHHH
VHQKAAVLYRKQARFQLITTGKISQKNLLFEEQHLERLRTASRYFAFPYDAEDLRQKIEA
HHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
ECQSCDIDQDYRLRISLSKSGEIELSRQILTPLSLHFCQAKLCLQEANLQQAFTYFKTTY
HHHHCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPHLNLGEQEIIYHNKSGELLETSIGNLVLKIAGKLYTPPIRLGILPGIYRQYLLETGQV
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHCCCH
EEKVLTLTDFAQAEAIYGCNAVRGLYELSLEEN
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHRKTVIDFRALGERYIFTKPIKELKTRNLTEVADLLAQVESYQEQGYYVVGYVSYEAAP
CCCCEEEHHHHCCCCCEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCC
AFEEKLAVHKAPLLGEYLLYFTVHDRVETSPIPLTYDEVDLPSNWQEVTSAADYEKAIAQ
HHHHHHHHHCCCHHHCEEEEEEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
IHHHLRQGDTYQVNYTVQLKQDLSANPFAIYNRMVVEQEAGYNAYVEHDDMAVISMSPEL
HHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHHHHEECCCCCCEEEECCCEEEEEECCHH
FFEQNDRELTTRPMKGTTQRAITDQEDLEQASWLEQDSKNRSENMMIVDLLRNDMNRISE
EEECCCCEEECCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
VGSEHVERLCQVEQYSTVWQMTSTIKSQLRADVDLVTIFRSLFPCGSITGAPKIATMEII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHH
KDLEPQPRGVYCGTIGLLHPNGRRIFNVAIRTIQLHQGEAIYGVGGGITWDSTWQSEYRE
HHCCCCCCEEEEEEEEEECCCCCEEEEEEEEEEEEECCCEEEECCCCCCCCCCHHHHHHH
VHQKAAVLYRKQARFQLITTGKISQKNLLFEEQHLERLRTASRYFAFPYDAEDLRQKIEA
HHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
ECQSCDIDQDYRLRISLSKSGEIELSRQILTPLSLHFCQAKLCLQEANLQQAFTYFKTTY
HHHHCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPHLNLGEQEIIYHNKSGELLETSIGNLVLKIAGKLYTPPIRLGILPGIYRQYLLETGQV
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHCCCH
EEKVLTLTDFAQAEAIYGCNAVRGLYELSLEEN
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]