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The map label for this gene is ftsY [H]

Identifier: 116516398

GI number: 116516398

Start: 1131776

End: 1133053

Strand: Reverse

Name: ftsY [H]

Synonym: SPD_1101

Alternate gene names: 116516398

Gene position: 1133053-1131776 (Counterclockwise)

Preceding gene: 116515438

Following gene: 116515798

Centisome position: 55.38

GC content: 41.78

Gene sequence:

>1278_bases
ATGGGATTGTTTGACCGTCTATTCGGAAAAAAAGAAGAACCTAAAATCGAAGAAGTTGTAAAAGAAGCTCTGGAAAATCT
TGATTTGTCTGAAGATGTTGATCCTACCTTCACAGAAGTTGAGGAAGTTTCTCAGGAAGAAGCAGAGGTTGAAATTGTTG
AACAAGCTGTGTTCCAAGAAGAGGAAATCCAAGACACAGTTGAAGAAAGTCTGGATTTAGAGCCAGTTGTAGAAGTTTCT
CAAAAAGAAGTCGAAGAATTTCCACACTCAGAAGAAGGGAATACTGAGTTTCTAGAGACTATAGAAGAAAATAATTCTGA
AGTTCTTGAACCAGAAAGGCCTCAAGCAGAAGAAACCGTTCAGGAAAAATATGACCGCAGTCTTAAGAAAACTCGTACAG
GTTTCGGTGCCCGCTTGAATGCCTTCTTTGCTAACTTCCGCTCTGTTGACGAAGAATTTTTCGAGGAACTGGAAGAACTG
CTGATTATGAGTGATGTTGGTGTCCAAGTCGCTTCTAACTTAACGGAGGAACTACGTTACGAAGCCAAGCTTGAAAATGC
CAAGAAACCTGATGCACTTCGTCGTGTCATCATTGAGAAATTGGTTGAGCTTTATGAAAAGGATGGTAGCTACGATGAAA
GCATCCACTTCCAAGATAACTTGACAGTTATGCTCTTTGTTGGTGTGAATGGTGTTGGGAAAACAACTTCTATCGGAAAA
CTAGCCCACCGCTACAAACAAGCTGGTAAGAAGGTCATGCTGGTTGCAGCAGATACCTTCCGTGCGGGTGCAGTAGCTCA
GCTAGCTGAATGGGGCCGACGAGTAGATGTTCCAGTAGTAACTGGACCTGAAAAAGCTGATCCAGCCAGCGTGGTCTTTG
ATGGTATGGAACGTGCCGTGGCTGAAGGTATCGATATTCTCATGATTGATACTGCTGGTCGTCTGCAAAATAAGGATAAC
CTTATGGCTGAGTTGGAAAAGATTGGTCGTATTATCAAACGTGTTGTGCCAGAAGCACCACATGAAACCTTCTTGGCACT
TGATGCATCAACAGGTCAAAATGCCCTAGTACAGGCCAAAGAATTTTCGAAAATCACACCTTTAACGGGAATTGTTTTGA
CTAAGATTGATGGAACTGCTCGAGGAGGTGTGGTTCTAGCCATTCGTGAAGAACTCAATATTCCTGTAAAATTGATTGGT
TTTGGTGAAAAAATCGATGATATTGGAGAGTTTAACTCAGAAAACTTTATGAAAGGTCTCTTGGAAGGTTTAATCTAA

Upstream 100 bases:

>100_bases
TGAAGTAAAGGCAGCCGCAAATGTAGTGACGCCGATGACCAACGATGAGGAAGCTGTCGCCTGGGCTATCGAAGAATATG
TGCTAAAGGAGAACTAAGAT

Downstream 100 bases:

>100_bases
TCAGAAGCAAAAATCCTGCAAGGCATAAACTTGCAGGAAATTTTTTTATTCTAAGCGACCATCTTGACGATAGGTGATAT
CTGGTTGCCAAGTCCATTTG

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVS
QKEVEEFPHSEEGNTEFLETIEENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGK
LAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDN
LMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIG
FGEKIDDIGEFNSENFMKGLLEGLI

Sequences:

>Translated_425_residues
MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVS
QKEVEEFPHSEEGNTEFLETIEENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGK
LAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDN
LMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIG
FGEKIDDIGEFNSENFMKGLLEGLI
>Mature_424_residues
GLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQ
KEVEEFPHSEEGNTEFLETIEENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELL
IMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGKL
AHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNL
MAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGF
GEKIDDIGEFNSENFMKGLLEGLI

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=296, Percent_Identity=30.7432432432432, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI226371618, Length=209, Percent_Identity=35.8851674641148, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295424842, Length=307, Percent_Identity=26.0586319218241, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI23308697, Length=307, Percent_Identity=26.0586319218241, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI89061728, Length=144, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789874, Length=300, Percent_Identity=46, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788963, Length=201, Percent_Identity=37.3134328358209, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17539958, Length=273, Percent_Identity=30.4029304029304, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=26.6891891891892, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6325345, Length=304, Percent_Identity=33.2236842105263, Blast_Score=159, Evalue=6e-40,
Organism=Drosophila melanogaster, GI17647949, Length=283, Percent_Identity=29.6819787985866, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24641198, Length=223, Percent_Identity=26.9058295964126, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 47467; Mature: 47336

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQE
CCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIEENNSEVLEPERPQAEETV
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHH
QEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELRY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGK
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHH
LAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAV
HHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEECCCEECCCCCCCCHHHHHHHHHHHH
AEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAK
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHH
EFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEFNSENFMKGL
HHCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHHHHH
LEGLI
HHHCC
>Mature Secondary Structure 
GLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVSQEEAEVEIVEQAVFQE
CCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIEENNSEVLEPERPQAEETV
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHH
QEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELRY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTSIGK
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHH
LAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAV
HHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEECCCEECCCCCCCCHHHHHHHHHHHH
AEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKRVVPEAPHETFLALDASTGQNALVQAK
HCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHH
EFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEFNSENFMKGL
HHCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHHHHH
LEGLI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]