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The map label for this gene is aroB

Identifier: 116515270

GI number: 116515270

Start: 377098

End: 378201

Strand: Reverse

Name: aroB

Synonym: BCc_352

Alternate gene names: 116515270

Gene position: 378201-377098 (Counterclockwise)

Preceding gene: 116515271

Following gene: 116515269

Centisome position: 90.83

GC content: 21.38

Gene sequence:

>1104_bases
ATGATAGAAACAATACATGTTAATTTAAATAATTATAGTTATAATATATATATTGGTGAATATATATTCAATAATATGTT
TATATCATCAATTTTTCTAAAAAATAAAAATAATGTATTAATTACAAATAAAAAAATAGAAAAAAAAATTTTAAAGAATA
AAAATCAATATTTTTATAAAATCTTGAATAAAATTCATTATTTTTCTATTAATGATGGGGAAAATTATAAAAATTTATAT
GAAGTAGAGAAAATTATTTCATTTTTATTAAATAATTTATATGGTAGAGATCTAAATTTAATAGCTCTTGGTGGAGGAGT
TATTGGCGATATTACTGGATTCGTTGCTTCTATATTTCAAAGAGGTGTAAATTTTTTTCAAATTCCAACTACTTTATTAT
CTCAAGTAGATGCATCAATTGGTGGAAAAACAGGAGTAAATCATATTTTAGGTAAAAATATGATTGGTTCTTTTTGGCAA
CCAAAGGGAGTATTTATAGATATAAAATTTTTATCAACTTTACCTAAAAAAGAATTACTTTCAGGAATCGCAGAAATTAT
TAAATATGCAATTGTTTTTGATAAAATTTTCTTTATTTGGTTAGAAAATAATTTATTTAAAGTATTAAATTTACAAAAAA
AAGAATTATTATATTGTATTAAAAAATGTTGTGAGTTAAAAGTTAAAATTATTGAGAATGATGAAAAAGAAATTGGTAAT
CGAGTGTTTTTAAATTTAGGTCATAGTTTTGCGCATGCTATAGAAACTTTTACTGGTTATGGAAAATGGTTGCATGGTAA
TGCAGTTTCTGTTGGAATCATTATGTCATCTTATTTATCTTTTTATTTAAAATATTTAAAAAAATCAGAGTTATTAAACA
TCATTAACATATTTAATAACATTGGTTTACCTATTATAGGACCTAGTACTATGTTACCTCTTGATTATTTAAAATTAATG
ATGAGAGATAAGAAGGTTATAAATAAAAATCTTCGACTTGTCATACCAGTATCAATTGGAAAAGTTAAATTAATTTCTTC
TATTAAAGAAAATATTTTATTAGATTCTATTACGGCTTGTCAAGAAAGAAGGTTTTTTTCTTAA

Upstream 100 bases:

>100_bases
CCAAAATTTTAAGTTATATTTCAAATTTAAATTTTATTTAAAAAAAATACTAATATTAAAAATATTAAATTTCTTAAATT
ATATTAAAACTGAGTTTATT

Downstream 100 bases:

>100_bases
TTTATAAAATTAAATATAAATTTAATATTTATACTATTTTTTGAGAAAAAAATATTTTTAAAAATAAAATTTGTTAAAAA
TAATAAATAAATATTTTAGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MIETIHVNLNNYSYNIYIGEYIFNNMFISSIFLKNKNNVLITNKKIEKKILKNKNQYFYKILNKIHYFSINDGENYKNLY
EVEKIISFLLNNLYGRDLNLIALGGGVIGDITGFVASIFQRGVNFFQIPTTLLSQVDASIGGKTGVNHILGKNMIGSFWQ
PKGVFIDIKFLSTLPKKELLSGIAEIIKYAIVFDKIFFIWLENNLFKVLNLQKKELLYCIKKCCELKVKIIENDEKEIGN
RVFLNLGHSFAHAIETFTGYGKWLHGNAVSVGIIMSSYLSFYLKYLKKSELLNIINIFNNIGLPIIGPSTMLPLDYLKLM
MRDKKVINKNLRLVIPVSIGKVKLISSIKENILLDSITACQERRFFS

Sequences:

>Translated_367_residues
MIETIHVNLNNYSYNIYIGEYIFNNMFISSIFLKNKNNVLITNKKIEKKILKNKNQYFYKILNKIHYFSINDGENYKNLY
EVEKIISFLLNNLYGRDLNLIALGGGVIGDITGFVASIFQRGVNFFQIPTTLLSQVDASIGGKTGVNHILGKNMIGSFWQ
PKGVFIDIKFLSTLPKKELLSGIAEIIKYAIVFDKIFFIWLENNLFKVLNLQKKELLYCIKKCCELKVKIIENDEKEIGN
RVFLNLGHSFAHAIETFTGYGKWLHGNAVSVGIIMSSYLSFYLKYLKKSELLNIINIFNNIGLPIIGPSTMLPLDYLKLM
MRDKKVINKNLRLVIPVSIGKVKLISSIKENILLDSITACQERRFFS
>Mature_367_residues
MIETIHVNLNNYSYNIYIGEYIFNNMFISSIFLKNKNNVLITNKKIEKKILKNKNQYFYKILNKIHYFSINDGENYKNLY
EVEKIISFLLNNLYGRDLNLIALGGGVIGDITGFVASIFQRGVNFFQIPTTLLSQVDASIGGKTGVNHILGKNMIGSFWQ
PKGVFIDIKFLSTLPKKELLSGIAEIIKYAIVFDKIFFIWLENNLFKVLNLQKKELLYCIKKCCELKVKIIENDEKEIGN
RVFLNLGHSFAHAIETFTGYGKWLHGNAVSVGIIMSSYLSFYLKYLKKSELLNIINIFNNIGLPIIGPSTMLPLDYLKLM
MRDKKVINKNLRLVIPVSIGKVKLISSIKENILLDSITACQERRFFS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=45.7063711911357, Blast_Score=335, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6320332, Length=311, Percent_Identity=36.9774919614148, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_BUCCC (Q056Z3)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802899.1
- ProteinModelPortal:   Q056Z3
- SMR:   Q056Z3
- STRING:   Q056Z3
- EnsemblBacteria:   EBBUCT00000001507
- GeneID:   4440736
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_352
- eggNOG:   COG0337
- GeneTree:   EBGT00050000008095
- HOGENOM:   HBG632303
- OMA:   TERMISD
- BioCyc:   BAPH372461:BCC_352-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 42103; Mature: 42103

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETIHVNLNNYSYNIYIGEYIFNNMFISSIFLKNKNNVLITNKKIEKKILKNKNQYFYK
CCEEEEEEECCEEEEEEEHHHHHHHHHHHHHEEECCCCEEEECHHHHHHHHHCCCHHHHH
ILNKIHYFSINDGENYKNLYEVEKIISFLLNNLYGRDLNLIALGGGVIGDITGFVASIFQ
HHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGVNFFQIPTTLLSQVDASIGGKTGVNHILGKNMIGSFWQPKGVFIDIKFLSTLPKKELL
CCCCEEEHHHHHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCCEEEEEHHHHCCCHHHHH
SGIAEIIKYAIVFDKIFFIWLENNLFKVLNLQKKELLYCIKKCCELKVKIIENDEKEIGN
HHHHHHHHHHHHHHHHHEEEECCCHHHHHCCCHHHHHHHHHHHHHCEEHEECCCHHHHCC
RVFLNLGHSFAHAIETFTGYGKWLHGNAVSVGIIMSSYLSFYLKYLKKSELLNIINIFNN
EEEEECCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLPIIGPSTMLPLDYLKLMMRDKKVINKNLRLVIPVSIGKVKLISSIKENILLDSITAC
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
QERRFFS
HHCCCCC
>Mature Secondary Structure
MIETIHVNLNNYSYNIYIGEYIFNNMFISSIFLKNKNNVLITNKKIEKKILKNKNQYFYK
CCEEEEEEECCEEEEEEEHHHHHHHHHHHHHEEECCCCEEEECHHHHHHHHHCCCHHHHH
ILNKIHYFSINDGENYKNLYEVEKIISFLLNNLYGRDLNLIALGGGVIGDITGFVASIFQ
HHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGVNFFQIPTTLLSQVDASIGGKTGVNHILGKNMIGSFWQPKGVFIDIKFLSTLPKKELL
CCCCEEEHHHHHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCCEEEEEHHHHCCCHHHHH
SGIAEIIKYAIVFDKIFFIWLENNLFKVLNLQKKELLYCIKKCCELKVKIIENDEKEIGN
HHHHHHHHHHHHHHHHHEEEECCCHHHHHCCCHHHHHHHHHHHHHCEEHEECCCHHHHCC
RVFLNLGHSFAHAIETFTGYGKWLHGNAVSVGIIMSSYLSFYLKYLKKSELLNIINIFNN
EEEEECCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLPIIGPSTMLPLDYLKLMMRDKKVINKNLRLVIPVSIGKVKLISSIKENILLDSITAC
CCCCEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
QERRFFS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA