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The map label for this gene is clpP [H]

Identifier: 116515217

GI number: 116515217

Start: 331724

End: 332326

Strand: Direct

Name: clpP [H]

Synonym: BCc_293

Alternate gene names: 116515217

Gene position: 331724-332326 (Clockwise)

Preceding gene: 116515216

Following gene: 116515218

Centisome position: 79.67

GC content: 23.22

Gene sequence:

>603_bases
ATGAATAATATTAAAAAAAAAAATCAACAAAAAAACAATTTACTTATACCATTTGTAATTGAAAAAACAAATCATGGAGA
AAGATCATATGATATATTTTCTAAATTATTAAAAGAAAGAATAATTTTTATTACTGGGATAATCGATGATAATATCGCTA
GTATTGTTATATCTCAAATATTATTTCTAGAATCAGAAAATAAAAAAAAAGATATTTTTATATACATAAATTCTCCTGGA
GGTATTATAACATCAGGATTATCAATTTATGATACTATGCAATTTGTTCAACCTAAAATTAATACAATATGTATTGGACA
AGCGGTCTATGCAGCTATATTATTATGTTCAGGAAACAAAGGAAAAAGATTTAGTTTACCTCATGCTAGAATTATGTTAC
ATCAACCATTAGGTGGTTTTAAAGGACAAGCATCAGATATTATGATACACGCTCAAGAAATAAAAAAAATAAAAAAAATA
ATAAATAACTTATTATCTTATCATACCAAACAACCAATCAAAAAAATAAAAAAAGATACAGAACGTGATTACTTTTTTTC
AGCACAAGAAGCTATTAAGTATGGTTTAATTGATTCTTTTTAA

Upstream 100 bases:

>100_bases
TAAAAATATTTAAAATATATAAAATTTTATATAAAAAGTAATATAAATAAAAAAAATTTATATTAATTTAATATAAACAT
TTTTTAAAGAGAAATTAAAT

Downstream 100 bases:

>100_bases
AAAAAAGAAATATTTATAAATAAAAATGTTTTAAATAATCATAGAGAAAAAAATGGATAATACAATTGATAATCAAGATA
TTATATTATGTTCTTTTTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MNNIKKKNQQKNNLLIPFVIEKTNHGERSYDIFSKLLKERIIFITGIIDDNIASIVISQILFLESENKKKDIFIYINSPG
GIITSGLSIYDTMQFVQPKINTICIGQAVYAAILLCSGNKGKRFSLPHARIMLHQPLGGFKGQASDIMIHAQEIKKIKKI
INNLLSYHTKQPIKKIKKDTERDYFFSAQEAIKYGLIDSF

Sequences:

>Translated_200_residues
MNNIKKKNQQKNNLLIPFVIEKTNHGERSYDIFSKLLKERIIFITGIIDDNIASIVISQILFLESENKKKDIFIYINSPG
GIITSGLSIYDTMQFVQPKINTICIGQAVYAAILLCSGNKGKRFSLPHARIMLHQPLGGFKGQASDIMIHAQEIKKIKKI
INNLLSYHTKQPIKKIKKDTERDYFFSAQEAIKYGLIDSF
>Mature_200_residues
MNNIKKKNQQKNNLLIPFVIEKTNHGERSYDIFSKLLKERIIFITGIIDDNIASIVISQILFLESENKKKDIFIYINSPG
GIITSGLSIYDTMQFVQPKINTICIGQAVYAAILLCSGNKGKRFSLPHARIMLHQPLGGFKGQASDIMIHAQEIKKIKKI
INNLLSYHTKQPIKKIKKDTERDYFFSAQEAIKYGLIDSF

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=185, Percent_Identity=53.5135135135135, Blast_Score=220, Evalue=8e-58,
Organism=Escherichia coli, GI1786641, Length=196, Percent_Identity=57.1428571428571, Blast_Score=262, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17538017, Length=184, Percent_Identity=50.5434782608696, Blast_Score=203, Evalue=4e-53,
Organism=Drosophila melanogaster, GI20129427, Length=194, Percent_Identity=53.6082474226804, Blast_Score=224, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22790; Mature: 22790

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIKKKNQQKNNLLIPFVIEKTNHGERSYDIFSKLLKERIIFITGIIDDNIASIVISQI
CCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHH
LFLESENKKKDIFIYINSPGGIITSGLSIYDTMQFVQPKINTICIGQAVYAAILLCSGNK
HHHCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHEECCCC
GKRFSLPHARIMLHQPLGGFKGQASDIMIHAQEIKKIKKIINNLLSYHTKQPIKKIKKDT
CCEECCCHHEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ERDYFFSAQEAIKYGLIDSF
CHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNIKKKNQQKNNLLIPFVIEKTNHGERSYDIFSKLLKERIIFITGIIDDNIASIVISQI
CCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHH
LFLESENKKKDIFIYINSPGGIITSGLSIYDTMQFVQPKINTICIGQAVYAAILLCSGNK
HHHCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHEECCCC
GKRFSLPHARIMLHQPLGGFKGQASDIMIHAQEIKKIKKIINNLLSYHTKQPIKKIKKDT
CCEECCCHHEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ERDYFFSAQEAIKYGLIDSF
CHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]