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The map label for this gene is asnC [H]

Identifier: 116515154

GI number: 116515154

Start: 253255

End: 254640

Strand: Reverse

Name: asnC [H]

Synonym: BCc_221

Alternate gene names: 116515154

Gene position: 254640-253255 (Counterclockwise)

Preceding gene: 116515155

Following gene: 116515143

Centisome position: 61.16

GC content: 22.37

Gene sequence:

>1386_bases
ATGCCTATAACTTCTATATTAGACATTTATACAAAAAAAAAATATTTAAATAAAGAAATTACAATTAATGGATGGATTCG
AAGTAAAAGAACTTCAAAAATAGGAATATCTTTTTTAACTATAACTGATGGATCATCAATTAATACTATTCAAGTTATTG
CTAAAAAATCTTTATATAATTATGTAACAGAAATTATTAAACTTACTACAGGTTGTTCAGTTATTATATCTGGAGTTTTA
GTTTTATCTCCAGGAAATTTACAAATTTATGAAATTCAATCTAATAAAATTAAAGTAATTGGTTGGATAAAAAATCCTGA
AAAATATCCTATATCAGCAAAAAAACATACTATAGAACATCTTAGAAAATTTTGTCATTTACGACCACGTACAAATTTAA
TTAGTGCTATTTCTAGAATTAGAAATATAGTTTTTCAATCTTTAAATTTATTTTTATTTAACAAGCAATATTTATGGGTA
TCAACTCCTATTATTACTAGTCTTGATACAGAAGGTTCTAGTTCTATGTTTAAAGTATCTATGTTAGATAATAATAACCA
ATACACCAATAATAATAATAAAAAATTTTTTAAAAAAGATGTTTTTTTAACTGTTTCTGGACAATTAACATTAGAAGCTT
ATGCATGTGCTTTATCTAAAGTCTATTCTTTGGGACCTATTTTTAGAGCAGAAAATTCAAATACTAAAAAACATCTAACA
GAATTTTGGATGTTAGAAGTAGAAAAAGCTTTTTCAAATATTAATGATATCTCTAAATTTGCAGAAAAATTATTAAAATT
TTCTATTAGTTATGTTTTAGATAATTGTATTTCTGATTTAATTTTTCTACAAAAAAAATTAAATCGTAACATTATTTCAT
ATTTAAATGATTTTTTATATAAAGATTTTATTAATATTGAATATAGCGAAGTTATTAATATTTTACAAAAAAATAAAAAT
TCTTCTTATGAAAATATTAATTGGGGAGAAGATTTATCTTCAAGTCATGAAAAATATTTAGTACATAAATATTTTAAATC
TACTGTAATAGTAAGAAACTATCCAAGATTATTAAAAGCTTTTTATATGCGTATGAATAGCGATAACAAAACTGTTGCTG
CTTTTGATATTTTAGTTCCTAACATAGGAGAAATAATAGGAGGATCAGAAAGAGAAGATAGAATCATGTATTTAGAAAAA
AATATGAATAAAGTAGGTTTAAATTCAAAAAATTATTCTTGGTATAAAGATTTAAGAAAATATGGAACTATACCACACTC
TGGTTTTGGTTTGGGATTAGAAAGATTAATTATTTTTATTACTGGTATTAAAAATATTAGAGAATCTATTCCATTTCCGA
GAACGATTAGGCATGCAGATTTTTAA

Upstream 100 bases:

>100_bases
ATTAGAAATAATGATTATTAACATTATTAAAAAATTTATATATAAATAATTATATATATATTATAAATTTTAAAATTAAT
TTTTAATAAAGGTGACAATA

Downstream 100 bases:

>100_bases
AAATCTTTATTTGAATTAATCAAAATAAAGATTTTTATTTTTTTTGAAGCTTTGAAAATATTTAGATTATATTTATAATT
ATATAATATTTTTATATTGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MPITSILDIYTKKKYLNKEITINGWIRSKRTSKIGISFLTITDGSSINTIQVIAKKSLYNYVTEIIKLTTGCSVIISGVL
VLSPGNLQIYEIQSNKIKVIGWIKNPEKYPISAKKHTIEHLRKFCHLRPRTNLISAISRIRNIVFQSLNLFLFNKQYLWV
STPIITSLDTEGSSSMFKVSMLDNNNQYTNNNNKKFFKKDVFLTVSGQLTLEAYACALSKVYSLGPIFRAENSNTKKHLT
EFWMLEVEKAFSNINDISKFAEKLLKFSISYVLDNCISDLIFLQKKLNRNIISYLNDFLYKDFINIEYSEVINILQKNKN
SSYENINWGEDLSSSHEKYLVHKYFKSTVIVRNYPRLLKAFYMRMNSDNKTVAAFDILVPNIGEIIGGSEREDRIMYLEK
NMNKVGLNSKNYSWYKDLRKYGTIPHSGFGLGLERLIIFITGIKNIRESIPFPRTIRHADF

Sequences:

>Translated_461_residues
MPITSILDIYTKKKYLNKEITINGWIRSKRTSKIGISFLTITDGSSINTIQVIAKKSLYNYVTEIIKLTTGCSVIISGVL
VLSPGNLQIYEIQSNKIKVIGWIKNPEKYPISAKKHTIEHLRKFCHLRPRTNLISAISRIRNIVFQSLNLFLFNKQYLWV
STPIITSLDTEGSSSMFKVSMLDNNNQYTNNNNKKFFKKDVFLTVSGQLTLEAYACALSKVYSLGPIFRAENSNTKKHLT
EFWMLEVEKAFSNINDISKFAEKLLKFSISYVLDNCISDLIFLQKKLNRNIISYLNDFLYKDFINIEYSEVINILQKNKN
SSYENINWGEDLSSSHEKYLVHKYFKSTVIVRNYPRLLKAFYMRMNSDNKTVAAFDILVPNIGEIIGGSEREDRIMYLEK
NMNKVGLNSKNYSWYKDLRKYGTIPHSGFGLGLERLIIFITGIKNIRESIPFPRTIRHADF
>Mature_460_residues
PITSILDIYTKKKYLNKEITINGWIRSKRTSKIGISFLTITDGSSINTIQVIAKKSLYNYVTEIIKLTTGCSVIISGVLV
LSPGNLQIYEIQSNKIKVIGWIKNPEKYPISAKKHTIEHLRKFCHLRPRTNLISAISRIRNIVFQSLNLFLFNKQYLWVS
TPIITSLDTEGSSSMFKVSMLDNNNQYTNNNNKKFFKKDVFLTVSGQLTLEAYACALSKVYSLGPIFRAENSNTKKHLTE
FWMLEVEKAFSNINDISKFAEKLLKFSISYVLDNCISDLIFLQKKLNRNIISYLNDFLYKDFINIEYSEVINILQKNKNS
SYENINWGEDLSSSHEKYLVHKYFKSTVIVRNYPRLLKAFYMRMNSDNKTVAAFDILVPNIGEIIGGSEREDRIMYLEKN
MNKVGLNSKNYSWYKDLRKYGTIPHSGFGLGLERLIIFITGIKNIRESIPFPRTIRHADF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=454, Percent_Identity=39.2070484581498, Blast_Score=325, Evalue=6e-89,
Organism=Homo sapiens, GI4758762, Length=468, Percent_Identity=26.0683760683761, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI45439306, Length=341, Percent_Identity=28.4457478005865, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1787161, Length=467, Percent_Identity=50.5353319057816, Blast_Score=544, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71984122, Length=477, Percent_Identity=28.0922431865828, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17556372, Length=422, Percent_Identity=29.6208530805687, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17551876, Length=340, Percent_Identity=29.1176470588235, Blast_Score=114, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6319872, Length=462, Percent_Identity=39.8268398268398, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=462, Percent_Identity=28.5714285714286, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6323011, Length=475, Percent_Identity=26.7368421052632, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19922416, Length=443, Percent_Identity=34.5372460496614, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI19921528, Length=468, Percent_Identity=27.5641025641026, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17136276, Length=334, Percent_Identity=27.5449101796407, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53346; Mature: 53214

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50862 AA_TRNA_LIGASE_II ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITSILDIYTKKKYLNKEITINGWIRSKRTSKIGISFLTITDGSSINTIQVIAKKSLYN
CCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHH
YVTEIIKLTTGCSVIISGVLVLSPGNLQIYEIQSNKIKVIGWIKNPEKYPISAKKHTIEH
HHHHHHHHHCCHHHHHCCEEEECCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHH
LRKFCHLRPRTNLISAISRIRNIVFQSLNLFLFNKQYLWVSTPIITSLDTEGSSSMFKVS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEEECEEEEEECCEEEECCCCCCCCEEEEE
MLDNNNQYTNNNNKKFFKKDVFLTVSGQLTLEAYACALSKVYSLGPIFRAENSNTKKHLT
EECCCCCCCCCCCCEEEEEEEEEEEECCEEHHHHHHHHHHHHHCCCEEECCCCCHHHHHH
EFWMLEVEKAFSNINDISKFAEKLLKFSISYVLDNCISDLIFLQKKLNRNIISYLNDFLY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KDFINIEYSEVINILQKNKNSSYENINWGEDLSSSHEKYLVHKYFKSTVIVRNYPRLLKA
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCEEEECCCHHHHHH
FYMRMNSDNKTVAAFDILVPNIGEIIGGSEREDRIMYLEKNMNKVGLNSKNYSWYKDLRK
HHHHCCCCCCEEEEEEECCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHH
YGTIPHSGFGLGLERLIIFITGIKNIRESIPFPRTIRHADF
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PITSILDIYTKKKYLNKEITINGWIRSKRTSKIGISFLTITDGSSINTIQVIAKKSLYN
CHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHH
YVTEIIKLTTGCSVIISGVLVLSPGNLQIYEIQSNKIKVIGWIKNPEKYPISAKKHTIEH
HHHHHHHHHCCHHHHHCCEEEECCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHH
LRKFCHLRPRTNLISAISRIRNIVFQSLNLFLFNKQYLWVSTPIITSLDTEGSSSMFKVS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEEECEEEEEECCEEEECCCCCCCCEEEEE
MLDNNNQYTNNNNKKFFKKDVFLTVSGQLTLEAYACALSKVYSLGPIFRAENSNTKKHLT
EECCCCCCCCCCCCEEEEEEEEEEEECCEEHHHHHHHHHHHHHCCCEEECCCCCHHHHHH
EFWMLEVEKAFSNINDISKFAEKLLKFSISYVLDNCISDLIFLQKKLNRNIISYLNDFLY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KDFINIEYSEVINILQKNKNSSYENINWGEDLSSSHEKYLVHKYFKSTVIVRNYPRLLKA
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCEEEECCCHHHHHH
FYMRMNSDNKTVAAFDILVPNIGEIIGGSEREDRIMYLEKNMNKVGLNSKNYSWYKDLRK
HHHHCCCCCCEEEEEEECCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHH
YGTIPHSGFGLGLERLIIFITGIKNIRESIPFPRTIRHADF
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]