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The map label for this gene is gapA [H]

Identifier: 116515117

GI number: 116515117

Start: 212086

End: 213084

Strand: Direct

Name: gapA [H]

Synonym: BCc_181

Alternate gene names: 116515117

Gene position: 212086-213084 (Clockwise)

Preceding gene: 116515114

Following gene: 116515119

Centisome position: 50.94

GC content: 26.63

Gene sequence:

>999_bases
ATGAAAATTAGAATTGCCATAAATGGTTTTGGTCGTATAGGTCGAATGATTTTTAGAATAGCTCAAAATAGACCAAATAT
TCGAATTGTAGCTATTAATGATTTATTAGAATCTAAATATATAGCATATATGTTAAAATATGATTCAACACATGGTTTAT
TTTCAAAATCTGTACAAGAAAAAGATGGAAACATAGTAGTAAATAATAAAAAAGTTTATATTTTTTCAGAAAGAAAACCT
GAAAATATAGACTGGAAATTACATAAAATTGATATAGTAATTGAATCTACTGGAATATTTTTAACAAGTCAATCTGCTTC
AAAACATATAGACGCAGGAGCTAAAAAAGTTATATTAACAGGACCTTCAAAAGATGATACTCCAATGTTTGTTAGAGGAG
TAAATTTTAGTCAATATAATAATCAAAAAATAATTTCTAATGCGTCATGTACTACTAATTGTTTAGCACCTTTAGCAAAA
GTATTACATGATGAATTTGAAATTATTGAAGGATTGATGACTACTGTACACGCAACAACAGCTACTCAAAAAACAGTAGA
TGGAGTTTCATTAAAAGATTGGAGAGGTGGTAGAGGTTCATTACAAAATATTATTCCCGCTTCTACTGGAGCAGCTCAAG
CTGTAGGAAAAATTTTACCAGAATTAAATAAAAAAATTACAGGTATTGCATTTAGAGTTCCAGTTGCTAATGTATCAGTA
GTAGATTTTACTGTAAAATTAAATAAAAAAACAACTTATAAAAATATATGTTCAGTTATTAAATCAGCATCTGAAACATA
TATGAAAGATGTAATCGGATATACAAATGATGATGTAGTTTCTAGTGATTTTAACGGTTCTTCTTTAACATCTATATTTG
ATGAAAAAGCTGGATTATCACTAAATAAAAACTTTGTAAAATTAGTATCTTGGTATGATAATGAAATTGGATATTCAAAT
AAAGTTTTAGATTTAGCAGAATGGATAGCATTAAAATAA

Upstream 100 bases:

>100_bases
ATAATTAATAAAAATAAATAAAAATTAAAATTTTAACATTATTATATACATAACATATTAAATATTTTTAATATACTGTA
ATTTTTGGTAAATAACATAT

Downstream 100 bases:

>100_bases
TTGACAATTAATTTTAATAATAAATATTAAATTTATATATTATGACAGTATTCAAGATAATTTATTTTGATACTGTCAAG
TATCAATATTTTTATATAAA

Product: hypothetical protein

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKIRIAINGFGRIGRMIFRIAQNRPNIRIVAINDLLESKYIAYMLKYDSTHGLFSKSVQEKDGNIVVNNKKVYIFSERKP
ENIDWKLHKIDIVIESTGIFLTSQSASKHIDAGAKKVILTGPSKDDTPMFVRGVNFSQYNNQKIISNASCTTNCLAPLAK
VLHDEFEIIEGLMTTVHATTATQKTVDGVSLKDWRGGRGSLQNIIPASTGAAQAVGKILPELNKKITGIAFRVPVANVSV
VDFTVKLNKKTTYKNICSVIKSASETYMKDVIGYTNDDVVSSDFNGSSLTSIFDEKAGLSLNKNFVKLVSWYDNEIGYSN
KVLDLAEWIALK

Sequences:

>Translated_332_residues
MKIRIAINGFGRIGRMIFRIAQNRPNIRIVAINDLLESKYIAYMLKYDSTHGLFSKSVQEKDGNIVVNNKKVYIFSERKP
ENIDWKLHKIDIVIESTGIFLTSQSASKHIDAGAKKVILTGPSKDDTPMFVRGVNFSQYNNQKIISNASCTTNCLAPLAK
VLHDEFEIIEGLMTTVHATTATQKTVDGVSLKDWRGGRGSLQNIIPASTGAAQAVGKILPELNKKITGIAFRVPVANVSV
VDFTVKLNKKTTYKNICSVIKSASETYMKDVIGYTNDDVVSSDFNGSSLTSIFDEKAGLSLNKNFVKLVSWYDNEIGYSN
KVLDLAEWIALK
>Mature_332_residues
MKIRIAINGFGRIGRMIFRIAQNRPNIRIVAINDLLESKYIAYMLKYDSTHGLFSKSVQEKDGNIVVNNKKVYIFSERKP
ENIDWKLHKIDIVIESTGIFLTSQSASKHIDAGAKKVILTGPSKDDTPMFVRGVNFSQYNNQKIISNASCTTNCLAPLAK
VLHDEFEIIEGLMTTVHATTATQKTVDGVSLKDWRGGRGSLQNIIPASTGAAQAVGKILPELNKKITGIAFRVPVANVSV
VDFTVKLNKKTTYKNICSVIKSASETYMKDVIGYTNDDVVSSDFNGSSLTSIFDEKAGLSLNKNFVKLVSWYDNEIGYSN
KVLDLAEWIALK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=58.5585585585586, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=53.1722054380665, Blast_Score=378, Evalue=1e-105,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=67.5757575757576, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=34.3465045592705, Blast_Score=224, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=55.5882352941177, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=55.2941176470588, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=54.8672566371681, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=54.8672566371681, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=61.2121212121212, Blast_Score=415, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=61.2121212121212, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=59.3939393939394, Blast_Score=406, Evalue=1e-114,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=57.0996978851964, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=57.0996978851964, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=56.4954682779456, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=56.4954682779456, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=57.1428571428571, Blast_Score=381, Evalue=1e-106,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36766; Mature: 36766

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRIAINGFGRIGRMIFRIAQNRPNIRIVAINDLLESKYIAYMLKYDSTHGLFSKSVQE
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEHHHHHCCEEEEEEEECCCCCHHHHHHHC
KDGNIVVNNKKVYIFSERKPENIDWKLHKIDIVIESTGIFLTSQSASKHIDAGAKKVILT
CCCCEEEECCEEEEEECCCCCCCCEEEEEEEEEEEECCEEEECCCCHHHCCCCCCEEEEE
GPSKDDTPMFVRGVNFSQYNNQKIISNASCTTNCLAPLAKVLHDEFEIIEGLMTTVHATT
CCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQKTVDGVSLKDWRGGRGSLQNIIPASTGAAQAVGKILPELNKKITGIAFRVPVANVSV
CCHHHCCCCEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEE
VDFTVKLNKKTTYKNICSVIKSASETYMKDVIGYTNDDVVSSDFNGSSLTSIFDEKAGLS
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
LNKNFVKLVSWYDNEIGYSNKVLDLAEWIALK
CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKIRIAINGFGRIGRMIFRIAQNRPNIRIVAINDLLESKYIAYMLKYDSTHGLFSKSVQE
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEHHHHHCCEEEEEEEECCCCCHHHHHHHC
KDGNIVVNNKKVYIFSERKPENIDWKLHKIDIVIESTGIFLTSQSASKHIDAGAKKVILT
CCCCEEEECCEEEEEECCCCCCCCEEEEEEEEEEEECCEEEECCCCHHHCCCCCCEEEEE
GPSKDDTPMFVRGVNFSQYNNQKIISNASCTTNCLAPLAKVLHDEFEIIEGLMTTVHATT
CCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQKTVDGVSLKDWRGGRGSLQNIIPASTGAAQAVGKILPELNKKITGIAFRVPVANVSV
CCHHHCCCCEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEE
VDFTVKLNKKTTYKNICSVIKSASETYMKDVIGYTNDDVVSSDFNGSSLTSIFDEKAGLS
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCC
LNKNFVKLVSWYDNEIGYSNKVLDLAEWIALK
CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765846; 12089438; 7763501 [H]