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The map label for this gene is tktB [H]

Identifier: 116515000

GI number: 116515000

Start: 63507

End: 65504

Strand: Direct

Name: tktB [H]

Synonym: BCc_058

Alternate gene names: 116515000

Gene position: 63507-65504 (Clockwise)

Preceding gene: 116514999

Following gene: 116515001

Centisome position: 15.25

GC content: 26.98

Gene sequence:

>1998_bases
ATGTTATCTAGAAAAGATTTATCAAATGCATTAAGATTTTTAAGTATAGATGCTATTCAACAAGCTCAATCTGGTCATCC
AGGTGCTCCTATGGGAATGGCGGACATTGCTGAAGTATTATGGAGAGATTTTTTAAAACATAATCCGAATAATCCTGCTT
GGTTTAATAGAGATAGATTTATTTTATCTAATGGACATGCTTCTATGCTTTTATATAGTTTATTACATCTTTCCGGATAT
AATATATCTATAGAAGATTTAAAAAATTTTAGAAATTGTTATTCTAAAACACCTGGTCACCCTGAAATTAATTGTACGCC
TGGAGTAGAAATTACTACTGGACCATTAGGTCAAGGTTTAGCTTCAGGTATAGGAATGGCTATTTCAGAAAAATTATTAG
CGCAATATTTTAATAGAGAAAATTTTAATATTATTGATCATTATACTTGGATTTTTGTAGGTGATGGATGTTTAATGGAA
GGTATTTCTCATGAATCTTGTTCTTTAGCAGGTACTTTAAGTTTAGGTAAATTAATTGTTTTTTATGATAAAAATGGTAT
TTCTATTGATGGTGAAATTTCCGATTGGTTTACTGATGATACAAAAAAACGTTTTTTATCATATAATTGGCATGTAATAG
AAATTAATGGTCATGATTCAGAAGAAATTTCAAAAGCTATAATAATTGCTAAAAAAAATATTTTACAACCTTCTCTAATT
ATTTGTAATACTATTATTGGATTTGGTTCACCAAATAAATCTGGAAAATCTTCTGTTCATGGAGCTCCTTTAGGGAGAAA
CAAGAAAGTATTGTTAACACGTAAAAAATTAAAATGGTCTTATGCTCCTTTTTTTATTCCAAAAAATATTTATAAATTAT
GGAATGCTTGTGATTCTGGAAATAAAGCAGAAGAAAAATGGAATAATCTGTTTAATAAATACAAAAAAAAATATTTAGAT
TTATCAAATGAATATATTCGTCGTATTAATAATATATTACCTAATAACTTTAATGAGATAATAAGGAAATTATTATTTAA
TTTTAATCATTCATTAACGAATTGTTCTACACGAGAAGCATCACAAAAAGTTTTAGAAAATATCGGAAAATTTTTACCTG
AATTACTCGGAGGTTCAGCTGACTTAGCGCCTAGTAATTTAACTAAATGGTCTGGATCTAAGTCTATTAAAAAATATTTA
AGAGGAAATTATATTCATTATGGAGTAAGAGAATTTGGAATGACGGCTATTGCTAATGGTATTTATCATCATGGTGGTTT
TATTCCTTATACGGCTACATTTTTAGTATTTGTAGATTATGCACGTAATGCAATACGTATGTCTGCATTAATGAAAACAA
AACAAATATTTATTTATACTCATGATTCTATTGGATTAGGAGAAGATGGTCCAACGCATCAACCTATAGAACATATTTCT
TCTTTAAGAAATATACCGAATCTAAGTGTTTGGAGACCTTGTGATTCTGTAGAAACTGCTGTTTCTTGGTATTATGGAAT
AAAAAGAAAAGATGGTCCTACAGCTATAATATTATCTAGACAGAATATAAAACAATATTTAAAAACAAATGATCAAATCA
AACTTGTTTTTAAAGGTGCTTATATTTTAAGAGAATATGGGACAAATATTGATTTAATTATTATCGCAACTGGATCAGAA
ATACCTTTAGCTATAAAAGTAGCAAAAAAATTATATGAGTTAAATTATAATATTCGAGTTGTATCCATGGTATCTACTGA
CTGTTTTGATAATCAAAATTTAAAATATCGTGAATTAGTTTTACCAGATTCAATATATAATCGAGTATCTATTGAAGCTG
GCATTAGTGATTATTGGTATAAATATATAGGTTTTAAAGGTATTAGAATAGGAATTGATTCTTTTGGAGAATCTGGACCA
GGAAATAAATTATTTAAATTGTTTGGTTTTTCAGTAAAGAAAATTGTTTTACGTATTATTAAAAAATTTTTTAGTTAA

Upstream 100 bases:

>100_bases
CAGTTTAGTAGTGATCAACAAGAATTAGAAAATTTTTTATTTGATAAATTATAATTACTTTATTATTTTAAAAAATTATT
TTTATATATAAGGAAGGTAT

Downstream 100 bases:

>100_bases
AAATTTTTTATAAGTTCAATAAAATAAAAATAGAATTTCTTTATTTTAAATATTTAAATTATATATAAATAACATTAGGA
TATATATTTATGCATACTAA

Product: TktB

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MLSRKDLSNALRFLSIDAIQQAQSGHPGAPMGMADIAEVLWRDFLKHNPNNPAWFNRDRFILSNGHASMLLYSLLHLSGY
NISIEDLKNFRNCYSKTPGHPEINCTPGVEITTGPLGQGLASGIGMAISEKLLAQYFNRENFNIIDHYTWIFVGDGCLME
GISHESCSLAGTLSLGKLIVFYDKNGISIDGEISDWFTDDTKKRFLSYNWHVIEINGHDSEEISKAIIIAKKNILQPSLI
ICNTIIGFGSPNKSGKSSVHGAPLGRNKKVLLTRKKLKWSYAPFFIPKNIYKLWNACDSGNKAEEKWNNLFNKYKKKYLD
LSNEYIRRINNILPNNFNEIIRKLLFNFNHSLTNCSTREASQKVLENIGKFLPELLGGSADLAPSNLTKWSGSKSIKKYL
RGNYIHYGVREFGMTAIANGIYHHGGFIPYTATFLVFVDYARNAIRMSALMKTKQIFIYTHDSIGLGEDGPTHQPIEHIS
SLRNIPNLSVWRPCDSVETAVSWYYGIKRKDGPTAIILSRQNIKQYLKTNDQIKLVFKGAYILREYGTNIDLIIIATGSE
IPLAIKVAKKLYELNYNIRVVSMVSTDCFDNQNLKYRELVLPDSIYNRVSIEAGISDYWYKYIGFKGIRIGIDSFGESGP
GNKLFKLFGFSVKKIVLRIIKKFFS

Sequences:

>Translated_665_residues
MLSRKDLSNALRFLSIDAIQQAQSGHPGAPMGMADIAEVLWRDFLKHNPNNPAWFNRDRFILSNGHASMLLYSLLHLSGY
NISIEDLKNFRNCYSKTPGHPEINCTPGVEITTGPLGQGLASGIGMAISEKLLAQYFNRENFNIIDHYTWIFVGDGCLME
GISHESCSLAGTLSLGKLIVFYDKNGISIDGEISDWFTDDTKKRFLSYNWHVIEINGHDSEEISKAIIIAKKNILQPSLI
ICNTIIGFGSPNKSGKSSVHGAPLGRNKKVLLTRKKLKWSYAPFFIPKNIYKLWNACDSGNKAEEKWNNLFNKYKKKYLD
LSNEYIRRINNILPNNFNEIIRKLLFNFNHSLTNCSTREASQKVLENIGKFLPELLGGSADLAPSNLTKWSGSKSIKKYL
RGNYIHYGVREFGMTAIANGIYHHGGFIPYTATFLVFVDYARNAIRMSALMKTKQIFIYTHDSIGLGEDGPTHQPIEHIS
SLRNIPNLSVWRPCDSVETAVSWYYGIKRKDGPTAIILSRQNIKQYLKTNDQIKLVFKGAYILREYGTNIDLIIIATGSE
IPLAIKVAKKLYELNYNIRVVSMVSTDCFDNQNLKYRELVLPDSIYNRVSIEAGISDYWYKYIGFKGIRIGIDSFGESGP
GNKLFKLFGFSVKKIVLRIIKKFFS
>Mature_665_residues
MLSRKDLSNALRFLSIDAIQQAQSGHPGAPMGMADIAEVLWRDFLKHNPNNPAWFNRDRFILSNGHASMLLYSLLHLSGY
NISIEDLKNFRNCYSKTPGHPEINCTPGVEITTGPLGQGLASGIGMAISEKLLAQYFNRENFNIIDHYTWIFVGDGCLME
GISHESCSLAGTLSLGKLIVFYDKNGISIDGEISDWFTDDTKKRFLSYNWHVIEINGHDSEEISKAIIIAKKNILQPSLI
ICNTIIGFGSPNKSGKSSVHGAPLGRNKKVLLTRKKLKWSYAPFFIPKNIYKLWNACDSGNKAEEKWNNLFNKYKKKYLD
LSNEYIRRINNILPNNFNEIIRKLLFNFNHSLTNCSTREASQKVLENIGKFLPELLGGSADLAPSNLTKWSGSKSIKKYL
RGNYIHYGVREFGMTAIANGIYHHGGFIPYTATFLVFVDYARNAIRMSALMKTKQIFIYTHDSIGLGEDGPTHQPIEHIS
SLRNIPNLSVWRPCDSVETAVSWYYGIKRKDGPTAIILSRQNIKQYLKTNDQIKLVFKGAYILREYGTNIDLIIIATGSE
IPLAIKVAKKLYELNYNIRVVSMVSTDCFDNQNLKYRELVLPDSIYNRVSIEAGISDYWYKYIGFKGIRIGIDSFGESGP
GNKLFKLFGFSVKKIVLRIIKKFFS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=674, Percent_Identity=26.1127596439169, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI4507521, Length=674, Percent_Identity=26.1127596439169, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI133778974, Length=265, Percent_Identity=29.811320754717, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=61.1195158850227, Blast_Score=885, Evalue=0.0,
Organism=Escherichia coli, GI48994911, Length=659, Percent_Identity=59.3323216995448, Blast_Score=875, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=264, Percent_Identity=29.1666666666667, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=45.059880239521, Blast_Score=556, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6325331, Length=667, Percent_Identity=45.1274362818591, Blast_Score=555, Evalue=1e-159,
Organism=Drosophila melanogaster, GI45551847, Length=670, Percent_Identity=26.5671641791045, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI45550715, Length=670, Percent_Identity=26.5671641791045, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24666278, Length=674, Percent_Identity=24.6290801186944, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24645119, Length=636, Percent_Identity=25.6289308176101, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 75287; Mature: 75287

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRKDLSNALRFLSIDAIQQAQSGHPGAPMGMADIAEVLWRDFLKHNPNNPAWFNRDRF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEE
ILSNGHASMLLYSLLHLSGYNISIEDLKNFRNCYSKTPGHPEINCTPGVEITTGPLGQGL
EEECCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHH
ASGIGMAISEKLLAQYFNRENFNIIDHYTWIFVGDGCLMEGISHESCSLAGTLSLGKLIV
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHCCCCCCCCCEEEEECCCCEEE
FYDKNGISIDGEISDWFTDDTKKRFLSYNWHVIEINGHDSEEISKAIIIAKKNILQPSLI
EECCCCCEECCCCHHHHCCHHHHHHEECCEEEEEECCCCHHHHHHHHEEEHHCCCCCHHH
ICNTIIGFGSPNKSGKSSVHGAPLGRNKKVLLTRKKLKWSYAPFFIPKNIYKLWNACDSG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECHHHHHHHHHHCCCC
NKAEEKWNNLFNKYKKKYLDLSNEYIRRINNILPNNFNEIIRKLLFNFNHSLTNCSTREA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHH
SQKVLENIGKFLPELLGGSADLAPSNLTKWSGSKSIKKYLRGNYIHYGVREFGMTAIANG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHH
IYHHGGFIPYTATFLVFVDYARNAIRMSALMKTKQIFIYTHDSIGLGEDGPTHQPIEHIS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCCCCHHHHHH
SLRNIPNLSVWRPCDSVETAVSWYYGIKRKDGPTAIILSRQNIKQYLKTNDQIKLVFKGA
HHHCCCCCCEECCCHHHHHHHHHHHCCEECCCCCEEEEEHHHHHHHHCCCCCEEEEEECH
YILREYGTNIDLIIIATGSEIPLAIKVAKKLYELNYNIRVVSMVSTDCFDNQNLKYRELV
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEE
LPDSIYNRVSIEAGISDYWYKYIGFKGIRIGIDSFGESGPGNKLFKLFGFSVKKIVLRII
CCHHHHCCEEEECCCHHHHHHHHCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KKFFS
HHHCC
>Mature Secondary Structure
MLSRKDLSNALRFLSIDAIQQAQSGHPGAPMGMADIAEVLWRDFLKHNPNNPAWFNRDRF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEE
ILSNGHASMLLYSLLHLSGYNISIEDLKNFRNCYSKTPGHPEINCTPGVEITTGPLGQGL
EEECCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHH
ASGIGMAISEKLLAQYFNRENFNIIDHYTWIFVGDGCLMEGISHESCSLAGTLSLGKLIV
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHCCCCCCCCCEEEEECCCCEEE
FYDKNGISIDGEISDWFTDDTKKRFLSYNWHVIEINGHDSEEISKAIIIAKKNILQPSLI
EECCCCCEECCCCHHHHCCHHHHHHEECCEEEEEECCCCHHHHHHHHEEEHHCCCCCHHH
ICNTIIGFGSPNKSGKSSVHGAPLGRNKKVLLTRKKLKWSYAPFFIPKNIYKLWNACDSG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECHHHHHHHHHHCCCC
NKAEEKWNNLFNKYKKKYLDLSNEYIRRINNILPNNFNEIIRKLLFNFNHSLTNCSTREA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHH
SQKVLENIGKFLPELLGGSADLAPSNLTKWSGSKSIKKYLRGNYIHYGVREFGMTAIANG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHH
IYHHGGFIPYTATFLVFVDYARNAIRMSALMKTKQIFIYTHDSIGLGEDGPTHQPIEHIS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCCCCHHHHHH
SLRNIPNLSVWRPCDSVETAVSWYYGIKRKDGPTAIILSRQNIKQYLKTNDQIKLVFKGA
HHHCCCCCCEECCCHHHHHHHHHHHCCEECCCCCEEEEEHHHHHHHHCCCCCEEEEEECH
YILREYGTNIDLIIIATGSEIPLAIKVAKKLYELNYNIRVVSMVSTDCFDNQNLKYRELV
HHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEE
LPDSIYNRVSIEAGISDYWYKYIGFKGIRIGIDSFGESGPGNKLFKLFGFSVKKIVLRII
CCHHHHCCEEEECCCHHHHHHHHCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KKFFS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]