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The map label for this gene is ruvB

Identifier: 116494313

GI number: 116494313

Start: 763427

End: 764443

Strand: Direct

Name: ruvB

Synonym: LSEI_0769

Alternate gene names: 116494313

Gene position: 763427-764443 (Clockwise)

Preceding gene: 116494312

Following gene: 116494314

Centisome position: 26.37

GC content: 49.26

Gene sequence:

>1017_bases
TTGGCAGACGCAGACAAGGATCGCTTGGTTTCTGGCGACGTTGACGATTCGAATGAAGCACAGATTGAAAAAAGTTTACG
TCCCCGGATGCTCGCGCAGTATATTGGTCAGGATCGCGTCAAACATCAGTTGGAAGTCTATATCACGGCTGCCAAACAGC
GCGAAGAGTCATTGGATCATGTTCTGCTCTATGGACCGCCTGGTTTGGGGAAAACGACGTTGGCTTTGGTGATTGCCAAT
GAACTGGGCGTCAATATTCGCACGACATCAGGGCCTGCTATCGAAAAACCGGGTGATTTAGTGGCATTGCTGAATGAATT
GCATCCCGGTGATGTCTTGTTCATTGATGAAATTCACCGTCTACCAAAAATTGTCGAAGAAATGCTTTATTCAGCGATGG
AAGATTTTTATATTGATATTGTGGTTGGTCAAGGGCCAACCGCCCACCCTGTGCATTTCCCGCTTCCTCCCTTCACCTTA
ATTGGGGCGACAACGCGCGCTGGCATGCTTTCCGCTCCGTTACGTGATCGATTTGGCATCAGTGAACATATGGCGTATTA
TTCTGCTGATGACCTCAGTGAGATCGTCAAACGATCAGCAACAATTTTCGATATGGCGATTGATGCTGAAGGTGCTCATG
AAATTGCCCGACGGTCGCGGGGAACACCGCGGGTTGCTAATCGGCTGCTCAAACGTATCCGTGATTTTGCCGAAGTTGCG
GGGCAGAGTCCAGTTGATATACAAATGGTTGACCATGCGCTTGACCAGCTGCAAGTCGATCAGCAAGGCTTAGACCAAAT
TGATCGCAAACTGTTGATGTTCATGATTCGTGATTACGAAGGCGGCCCCGTTGGACTTTCAACGATTGCCGCTAACATCG
GCGAGGAAATGGCAACGATTGAGGAAATGTATGAGCCTTATCTGTTACAGATCGGGTATTTGAAACGAACGCCGCGTGGC
CGCATGGTGACGCCAGCCGGATTTGCACATATGGGGATGTCGGCTGAGCAACATTAG

Upstream 100 bases:

>100_bases
ACTGAAGCTGACCGTTGACGACAACGGAAGCGGCTTTTGAATCACGATAAAATTTTTCCCGTGCTTTTAATAGCATGTTA
ACTAGAGAGGAAGTGGGTTT

Downstream 100 bases:

>100_bases
GCAACATGCTAACCGCGCTGGCTCGCGCTCAACTATAACGCGCTCGCAGTCGCAGAAGCCTGCACATAAGGACCTTGAAG
CCTAAATGGCCAAAATTCAG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MADADKDRLVSGDVDDSNEAQIEKSLRPRMLAQYIGQDRVKHQLEVYITAAKQREESLDHVLLYGPPGLGKTTLALVIAN
ELGVNIRTTSGPAIEKPGDLVALLNELHPGDVLFIDEIHRLPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTL
IGATTRAGMLSAPLRDRFGISEHMAYYSADDLSEIVKRSATIFDMAIDAEGAHEIARRSRGTPRVANRLLKRIRDFAEVA
GQSPVDIQMVDHALDQLQVDQQGLDQIDRKLLMFMIRDYEGGPVGLSTIAANIGEEMATIEEMYEPYLLQIGYLKRTPRG
RMVTPAGFAHMGMSAEQH

Sequences:

>Translated_338_residues
MADADKDRLVSGDVDDSNEAQIEKSLRPRMLAQYIGQDRVKHQLEVYITAAKQREESLDHVLLYGPPGLGKTTLALVIAN
ELGVNIRTTSGPAIEKPGDLVALLNELHPGDVLFIDEIHRLPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTL
IGATTRAGMLSAPLRDRFGISEHMAYYSADDLSEIVKRSATIFDMAIDAEGAHEIARRSRGTPRVANRLLKRIRDFAEVA
GQSPVDIQMVDHALDQLQVDQQGLDQIDRKLLMFMIRDYEGGPVGLSTIAANIGEEMATIEEMYEPYLLQIGYLKRTPRG
RMVTPAGFAHMGMSAEQH
>Mature_337_residues
ADADKDRLVSGDVDDSNEAQIEKSLRPRMLAQYIGQDRVKHQLEVYITAAKQREESLDHVLLYGPPGLGKTTLALVIANE
LGVNIRTTSGPAIEKPGDLVALLNELHPGDVLFIDEIHRLPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTLI
GATTRAGMLSAPLRDRFGISEHMAYYSADDLSEIVKRSATIFDMAIDAEGAHEIARRSRGTPRVANRLLKRIRDFAEVAG
QSPVDIQMVDHALDQLQVDQQGLDQIDRKLLMFMIRDYEGGPVGLSTIAANIGEEMATIEEMYEPYLLQIGYLKRTPRGR
MVTPAGFAHMGMSAEQH

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=330, Percent_Identity=54.5454545454545, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_LACC3 (Q03B17)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806047.1
- ProteinModelPortal:   Q03B17
- SMR:   Q03B17
- STRING:   Q03B17
- GeneID:   4419392
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_0769
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q03B17
- ProtClustDB:   PRK00080
- BioCyc:   LCAS321967:LSEI_0769-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37499; Mature: 37367

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADADKDRLVSGDVDDSNEAQIEKSLRPRMLAQYIGQDRVKHQLEVYITAAKQREESLDH
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEHHHHHHHCCCE
VLLYGPPGLGKTTLALVIANELGVNIRTTSGPAIEKPGDLVALLNELHPGDVLFIDEIHR
EEEECCCCCCHHHHHEEEHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHH
LPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTLIGATTRAGMLSAPLRDRFGI
HHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCHHHHCCCHHCCHHCCCHHHHCCH
SEHMAYYSADDLSEIVKRSATIFDMAIDAEGAHEIARRSRGTPRVANRLLKRIRDFAEVA
HHHHHHCCHHHHHHHHHHCCHHEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GQSPVDIQMVDHALDQLQVDQQGLDQIDRKLLMFMIRDYEGGPVGLSTIAANIGEEMATI
CCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EEMYEPYLLQIGYLKRTPRGRMVTPAGFAHMGMSAEQH
HHHHCHHHEEHHHHHCCCCCCEECCCCHHHCCCCCCCC
>Mature Secondary Structure 
ADADKDRLVSGDVDDSNEAQIEKSLRPRMLAQYIGQDRVKHQLEVYITAAKQREESLDH
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEHHHHHHHCCCE
VLLYGPPGLGKTTLALVIANELGVNIRTTSGPAIEKPGDLVALLNELHPGDVLFIDEIHR
EEEECCCCCCHHHHHEEEHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHH
LPKIVEEMLYSAMEDFYIDIVVGQGPTAHPVHFPLPPFTLIGATTRAGMLSAPLRDRFGI
HHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCHHHHCCCHHCCHHCCCHHHHCCH
SEHMAYYSADDLSEIVKRSATIFDMAIDAEGAHEIARRSRGTPRVANRLLKRIRDFAEVA
HHHHHHCCHHHHHHHHHHCCHHEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GQSPVDIQMVDHALDQLQVDQQGLDQIDRKLLMFMIRDYEGGPVGLSTIAANIGEEMATI
CCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EEMYEPYLLQIGYLKRTPRGRMVTPAGFAHMGMSAEQH
HHHHCHHHEEHHHHHCCCCCCEECCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA