Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 116494312

GI number: 116494312

Start: 762720

End: 763316

Strand: Direct

Name: ruvA

Synonym: LSEI_0768

Alternate gene names: 116494312

Gene position: 762720-763316 (Clockwise)

Preceding gene: 116494310

Following gene: 116494313

Centisome position: 26.34

GC content: 51.42

Gene sequence:

>597_bases
ATGTACGAGTATTTTGAAGGCATTATTCAGGCGGTGACCCCGGCTTACATCGTCATCGATGTGCATGGCATCGGGTTCCG
TCTGCTGGTAGCCAACCCTTATCATTTTGAAGCTGGCGAGCAAAAACGTGTTTATGTGCAGCTGATCATTCGCGACAACG
ACCAGACACTTTATGGATTCGAAGGTGCTGCGGATAAGCGTACCTTTAACCAGCTATTGACGGTCACAGGCATTGGCCCG
AAGTCAGCGTTGGCCATTTTGGCGAACGTGTCTAGCGGCGGCTTGGCGACTGCGATTGCTCAAGATGATGTGAAGTTTCT
GACTAAGTTTCCTGGGATCGGTAAGAAAACAGCTGCCCAGATTATCCTTGATCTCAAAGGTAAAATCACAACAGATGGAC
AACCAGCGGCAGCAGCGATTGCGCCAGTTGCCAGTGACGTTGATTCGGAACTCGCAGATGCGTTGGCGGCACTCGTGGCA
TTGGGCTACCCGCAACGCACCGTTGATGGTCTCACTGACACACTGAAGGCATTCAGTGCCAAGACAACTGATGCCTATTT
ACGCGAAGGCTTGCGGCTATTAAGCGGCAAGGCTTAG

Upstream 100 bases:

>100_bases
GGATTCATATATTTTTGGCCTCAGAACAGTTCATCATCAGGAAAACATCTATGCTACAATGAATCAAGCATACCAAACAT
ACGTACTGAATGGAGAGCTT

Downstream 100 bases:

>100_bases
GCTTGATTATACTGAAGCTGACCGTTGACGACAACGGAAGCGGCTTTTGAATCACGATAAAATTTTTCCCGTGCTTTTAA
TAGCATGTTAACTAGAGAGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MYEYFEGIIQAVTPAYIVIDVHGIGFRLLVANPYHFEAGEQKRVYVQLIIRDNDQTLYGFEGAADKRTFNQLLTVTGIGP
KSALAILANVSSGGLATAIAQDDVKFLTKFPGIGKKTAAQIILDLKGKITTDGQPAAAAIAPVASDVDSELADALAALVA
LGYPQRTVDGLTDTLKAFSAKTTDAYLREGLRLLSGKA

Sequences:

>Translated_198_residues
MYEYFEGIIQAVTPAYIVIDVHGIGFRLLVANPYHFEAGEQKRVYVQLIIRDNDQTLYGFEGAADKRTFNQLLTVTGIGP
KSALAILANVSSGGLATAIAQDDVKFLTKFPGIGKKTAAQIILDLKGKITTDGQPAAAAIAPVASDVDSELADALAALVA
LGYPQRTVDGLTDTLKAFSAKTTDAYLREGLRLLSGKA
>Mature_198_residues
MYEYFEGIIQAVTPAYIVIDVHGIGFRLLVANPYHFEAGEQKRVYVQLIIRDNDQTLYGFEGAADKRTFNQLLTVTGIGP
KSALAILANVSSGGLATAIAQDDVKFLTKFPGIGKKTAAQIILDLKGKITTDGQPAAAAIAPVASDVDSELADALAALVA
LGYPQRTVDGLTDTLKAFSAKTTDAYLREGLRLLSGKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=32.3383084577114, Blast_Score=107, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_LACC3 (Q03B18)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806046.1
- ProteinModelPortal:   Q03B18
- SMR:   Q03B18
- STRING:   Q03B18
- GeneID:   4419391
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_0768
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q03B18
- ProtClustDB:   PRK00116
- BioCyc:   LCAS321967:LSEI_0768-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21032; Mature: 21032

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEYFEGIIQAVTPAYIVIDVHGIGFRLLVANPYHFEAGEQKRVYVQLIIRDNDQTLYGF
CHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCEECCCCCCCEEEEEEEEECCCCEEEEC
EGAADKRTFNQLLTVTGIGPKSALAILANVSSGGLATAIAQDDVKFLTKFPGIGKKTAAQ
CCCCCHHHHHHHEEEECCCHHHHEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCHHHHHH
IILDLKGKITTDGQPAAAAIAPVASDVDSELADALAALVALGYPQRTVDGLTDTLKAFSA
HHEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
KTTDAYLREGLRLLSGKA
CCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYEYFEGIIQAVTPAYIVIDVHGIGFRLLVANPYHFEAGEQKRVYVQLIIRDNDQTLYGF
CHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCEECCCCCCCEEEEEEEEECCCCEEEEC
EGAADKRTFNQLLTVTGIGPKSALAILANVSSGGLATAIAQDDVKFLTKFPGIGKKTAAQ
CCCCCHHHHHHHEEEECCCHHHHEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCHHHHHH
IILDLKGKITTDGQPAAAAIAPVASDVDSELADALAALVALGYPQRTVDGLTDTLKAFSA
HHEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
KTTDAYLREGLRLLSGKA
CCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA