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The map label for this gene is yfnA [H]

Identifier: 116494183

GI number: 116494183

Start: 630162

End: 631637

Strand: Direct

Name: yfnA [H]

Synonym: LSEI_0633

Alternate gene names: 116494183

Gene position: 630162-631637 (Clockwise)

Preceding gene: 116494182

Following gene: 116494185

Centisome position: 21.77

GC content: 50.34

Gene sequence:

>1476_bases
ATGGGGCAAGTTTGGCAACGATTGATTAGAAAAGAAGATCCAAGTGTTTATGAAGATAAGGATTCACATTTACCGCGCGT
TTTACGCGTCCGCGATTTTCTTGCGTTAGGGGTCGGGACGATTGTGTCGGCTTCGATTTTTACATTACCAGGGGTGGTGG
CGGCAAAACATGCTGGTCCCGCTGTGTCGATTTCTTTCTTAGTAGCCGCGATAGTCGCAGGGCTGGTTGCGTTTGCCTAC
GCGGAAATGTCAGCGGCGATGCCATTTGCCGGTTCGGCTTATTCTTGGATCAATGTTGTTTTCGGCGAATTTTTTGGCTG
GATTGCCGGCTGGGCTTTATTGGCGGAATACTTTATCGCAGTGGCGTTTGTGGCGTCAGGACTTTCAGCTAATTTCCGCG
GGCTGCTGGCAACCATTGGCGTGAATTTTCCTAAAGCCTTGGCGAATCCGGTTGGGACCGATGGTGGCATGGTCGATCTC
GTTGCAGTGGTCGTCATGGTGCTGGTCGGCTTGTTACTGTCGCGGGGGGTATCAAGTGCTGCGCGCGTTGAAAACATCTT
GGTTGTCATGAAGGTGCTGGCAATCCTGCTTTTCTTGGTGGTCGGCTTGACTGCGATTCACCCTGAAAACTTCCATCCAT
TCTTTCCTGCTTATCATCTCAATGCTGACGGTACACCATTTGGTGGTTGGCAGGGGATCTATGCCGGAGTTTCAATGATT
TTCCTTGCTTATATTGGCTTTGATTCCATCGCTGCTAATTCTGCGGAAGCCATTGACCCAGAGAAAACGATGCCACGCGG
TATTCTAGGTTCGTTACTGATTGCAGTGTTCTTGTTCGTTTCGGTTGGTCTTGTGTTGTTAGGTATGTTCCCATATCAGG
ATTATGCCAATAACGCGGAGCCCGTTGGCTGGGCATTGCGTCATTCTGGCCATGCAGTCGTTGCCGTTGTGGTTGAAAGC
ATTGCGGTCTTAGGAATGTTCACGGCTTTGATCGGGATGTCCATGGCTGGGTCGCGCTTGCTTTACAGTTTTGGCCGTGA
TGGCATGCTGCCGAAAAAACTGGGTAAGCTGAACAGTCGTAAGCTGCCTAATCATGCCTTGGCTGTTTTGATTACCATCG
GCGTTTTGATCGGCGCTTTCTTCCCGTTTGCCTTTTTGGCCCAACTGATTTCGGCTGGCACCTTGATAGCCTTTATGTTC
GTGACACTGGGAATCTATCGATTGCGTCCGCGTGAAGGCCAAGATATCGCCAAACCGCGCTTCCGGATGCCACTGTATCC
AGTTTTGCCAGCAGTTGCCTTCCTGGGATCACTTATCGTTTTCCTTGGGCTCGACATTCAAGCCAAACTGTATTCCGGTG
TCTGGTTCCTGATCGGCTGTGCCATTTACTTCCTGTACGGCATGCGTCACTCGGCTCTGACAAAGGGATCAGCGGTTGAG
CAAGAAACTGCTGCGTTAGGACAAGAAAAAGATTAA

Upstream 100 bases:

>100_bases
CGCTTTCCAGCCAAGCTGAAATGTGCTAACCTATTTCTCATACGTTTTTTAAATATGTGAGAGACTGACTGCTTGATGAG
CAGTGCCATGGAGGTTACCG

Downstream 100 bases:

>100_bases
AAAAGCCGCTGCCTGAGATTGCCCGCGTTGTGACGCGCGGTCTCGGACAGCGGTTTTTTGGTACGGTGGCTTAGTGATAC
TCGTCTGGAGAGACACCGTT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MGQVWQRLIRKEDPSVYEDKDSHLPRVLRVRDFLALGVGTIVSASIFTLPGVVAAKHAGPAVSISFLVAAIVAGLVAFAY
AEMSAAMPFAGSAYSWINVVFGEFFGWIAGWALLAEYFIAVAFVASGLSANFRGLLATIGVNFPKALANPVGTDGGMVDL
VAVVVMVLVGLLLSRGVSSAARVENILVVMKVLAILLFLVVGLTAIHPENFHPFFPAYHLNADGTPFGGWQGIYAGVSMI
FLAYIGFDSIAANSAEAIDPEKTMPRGILGSLLIAVFLFVSVGLVLLGMFPYQDYANNAEPVGWALRHSGHAVVAVVVES
IAVLGMFTALIGMSMAGSRLLYSFGRDGMLPKKLGKLNSRKLPNHALAVLITIGVLIGAFFPFAFLAQLISAGTLIAFMF
VTLGIYRLRPREGQDIAKPRFRMPLYPVLPAVAFLGSLIVFLGLDIQAKLYSGVWFLIGCAIYFLYGMRHSALTKGSAVE
QETAALGQEKD

Sequences:

>Translated_491_residues
MGQVWQRLIRKEDPSVYEDKDSHLPRVLRVRDFLALGVGTIVSASIFTLPGVVAAKHAGPAVSISFLVAAIVAGLVAFAY
AEMSAAMPFAGSAYSWINVVFGEFFGWIAGWALLAEYFIAVAFVASGLSANFRGLLATIGVNFPKALANPVGTDGGMVDL
VAVVVMVLVGLLLSRGVSSAARVENILVVMKVLAILLFLVVGLTAIHPENFHPFFPAYHLNADGTPFGGWQGIYAGVSMI
FLAYIGFDSIAANSAEAIDPEKTMPRGILGSLLIAVFLFVSVGLVLLGMFPYQDYANNAEPVGWALRHSGHAVVAVVVES
IAVLGMFTALIGMSMAGSRLLYSFGRDGMLPKKLGKLNSRKLPNHALAVLITIGVLIGAFFPFAFLAQLISAGTLIAFMF
VTLGIYRLRPREGQDIAKPRFRMPLYPVLPAVAFLGSLIVFLGLDIQAKLYSGVWFLIGCAIYFLYGMRHSALTKGSAVE
QETAALGQEKD
>Mature_490_residues
GQVWQRLIRKEDPSVYEDKDSHLPRVLRVRDFLALGVGTIVSASIFTLPGVVAAKHAGPAVSISFLVAAIVAGLVAFAYA
EMSAAMPFAGSAYSWINVVFGEFFGWIAGWALLAEYFIAVAFVASGLSANFRGLLATIGVNFPKALANPVGTDGGMVDLV
AVVVMVLVGLLLSRGVSSAARVENILVVMKVLAILLFLVVGLTAIHPENFHPFFPAYHLNADGTPFGGWQGIYAGVSMIF
LAYIGFDSIAANSAEAIDPEKTMPRGILGSLLIAVFLFVSVGLVLLGMFPYQDYANNAEPVGWALRHSGHAVVAVVVESI
AVLGMFTALIGMSMAGSRLLYSFGRDGMLPKKLGKLNSRKLPNHALAVLITIGVLIGAFFPFAFLAQLISAGTLIAFMFV
TLGIYRLRPREGQDIAKPRFRMPLYPVLPAVAFLGSLIVFLGLDIQAKLYSGVWFLIGCAIYFLYGMRHSALTKGSAVEQ
ETAALGQEKD

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=432, Percent_Identity=29.8611111111111, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI4507047, Length=439, Percent_Identity=31.8906605922551, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI258614005, Length=433, Percent_Identity=30.0230946882217, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI258614003, Length=433, Percent_Identity=30.0230946882217, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI181337167, Length=406, Percent_Identity=30.7881773399015, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=29.6296296296296, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=29.6296296296296, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI110347453, Length=414, Percent_Identity=29.2270531400966, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI7657683, Length=411, Percent_Identity=25.0608272506083, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI33286428, Length=333, Percent_Identity=25.8258258258258, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI9790235, Length=298, Percent_Identity=25.503355704698, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI71999149, Length=392, Percent_Identity=26.2755102040816, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082250, Length=428, Percent_Identity=25.7009345794392, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786789, Length=449, Percent_Identity=24.2761692650334, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788480, Length=466, Percent_Identity=23.6051502145923, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789017, Length=428, Percent_Identity=25, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786602, Length=467, Percent_Identity=22.9122055674518, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081708, Length=483, Percent_Identity=22.1532091097308, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081869, Length=475, Percent_Identity=24.2105263157895, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994972, Length=481, Percent_Identity=23.2848232848233, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786302, Length=418, Percent_Identity=20.8133971291866, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790653, Length=349, Percent_Identity=27.2206303724928, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786694, Length=398, Percent_Identity=24.3718592964824, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI2367353, Length=375, Percent_Identity=24.5333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081915, Length=390, Percent_Identity=23.8461538461538, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082023, Length=460, Percent_Identity=23.4782608695652, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=466, Percent_Identity=29.1845493562232, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17531343, Length=420, Percent_Identity=30.2380952380952, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17533459, Length=423, Percent_Identity=29.0780141843972, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321053, Length=455, Percent_Identity=20.2197802197802, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=33.7264150943396, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=33.7264150943396, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=33.7264150943396, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24666159, Length=428, Percent_Identity=30.1401869158879, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI221512776, Length=428, Percent_Identity=30.1401869158879, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI281366235, Length=414, Percent_Identity=31.4009661835749, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI116007820, Length=414, Percent_Identity=31.4009661835749, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI161077963, Length=422, Percent_Identity=29.8578199052133, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=31.4009661835749, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=31.4009661835749, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24667468, Length=417, Percent_Identity=28.7769784172662, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52487; Mature: 52356

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQVWQRLIRKEDPSVYEDKDSHLPRVLRVRDFLALGVGTIVSASIFTLPGVVAAKHAGP
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
AVSISFLVAAIVAGLVAFAYAEMSAAMPFAGSAYSWINVVFGEFFGWIAGWALLAEYFIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFVASGLSANFRGLLATIGVNFPKALANPVGTDGGMVDLVAVVVMVLVGLLLSRGVSSA
HHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
ARVENILVVMKVLAILLFLVVGLTAIHPENFHPFFPAYHLNADGTPFGGWQGIYAGVSMI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHH
FLAYIGFDSIAANSAEAIDPEKTMPRGILGSLLIAVFLFVSVGLVLLGMFPYQDYANNAE
HHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
PVGWALRHSGHAVVAVVVESIAVLGMFTALIGMSMAGSRLLYSFGRDGMLPKKLGKLNSR
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHCCCCCC
KLPNHALAVLITIGVLIGAFFPFAFLAQLISAGTLIAFMFVTLGIYRLRPREGQDIAKPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FRMPLYPVLPAVAFLGSLIVFLGLDIQAKLYSGVWFLIGCAIYFLYGMRHSALTKGSAVE
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QETAALGQEKD
HHHHHCCCCCC
>Mature Secondary Structure 
GQVWQRLIRKEDPSVYEDKDSHLPRVLRVRDFLALGVGTIVSASIFTLPGVVAAKHAGP
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
AVSISFLVAAIVAGLVAFAYAEMSAAMPFAGSAYSWINVVFGEFFGWIAGWALLAEYFIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFVASGLSANFRGLLATIGVNFPKALANPVGTDGGMVDLVAVVVMVLVGLLLSRGVSSA
HHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
ARVENILVVMKVLAILLFLVVGLTAIHPENFHPFFPAYHLNADGTPFGGWQGIYAGVSMI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHH
FLAYIGFDSIAANSAEAIDPEKTMPRGILGSLLIAVFLFVSVGLVLLGMFPYQDYANNAE
HHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
PVGWALRHSGHAVVAVVVESIAVLGMFTALIGMSMAGSRLLYSFGRDGMLPKKLGKLNSR
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHCCCCCC
KLPNHALAVLITIGVLIGAFFPFAFLAQLISAGTLIAFMFVTLGIYRLRPREGQDIAKPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FRMPLYPVLPAVAFLGSLIVFLGLDIQAKLYSGVWFLIGCAIYFLYGMRHSALTKGSAVE
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QETAALGQEKD
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]