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The map label for this gene is sstT

Identifier: 116494182

GI number: 116494182

Start: 628636

End: 629940

Strand: Direct

Name: sstT

Synonym: LSEI_0632

Alternate gene names: 116494182

Gene position: 628636-629940 (Clockwise)

Preceding gene: 116494181

Following gene: 116494183

Centisome position: 21.71

GC content: 47.36

Gene sequence:

>1305_bases
ATGTATAAACGGTACAAAGATGTTTCGTTGATCTTAAAAATTGTCATTGGGATCATTGTTGGGGCAGTGTTAGGGGTAAT
GGTGCCCTCCTGGTCCTTTATTGATGTTCTCGGTAAATTATTCGTTGGCGCTTTAAAAGCGATTGCACCACTACTGGTCT
TTCTATTAATTATGTCGGCGATCTCTAAGTATCGCTCAGGTGCGAAGAACCACTTTGGCACCGTTATTGTGCTTTATCTC
AGTGCCACGTTGTTTTCATCAATTGCTGCCGTGGCGGTCTCGTATCTTTTTCCGATCAAATTGGTGTTGCCCGGTGCGAT
GAAGATCGCCGAAAGTGCACCGAAAGATCTGGGGACTGTTGTGACGAGCTTACTAACCAATGCCGTTGCCAATCCAATCT
CTGCATTGGTTGAAGGTAATTACCTAGCTATTCTTTTCTGGTCCTTACTGATCGGTTCCGGTTTACGATTGACCAGTGCT
GTGACCAAAAAGGTGGTCACGGAATTGGCCGATACTGTCAGCGCTGTCGCTCAAAATGTCATTCAGTTCGCACCGTTTGG
GATTGTCGGGTTGTTACACGAGTCCTTGAGTAAAACTGGTGTCAAAGGGGTCATGGCATATGGTCAGCTGCTCATGCTGC
TGGTTGCCACGATGGTATTTGTTTACTTAGTCGTGTACCCATTCATGGTTTGGTTGATGACCCGGCAAAATCCGTATCCG
TTGACTTTTTGGACGCTGAAAGTCAGTGGCATTCCGGCATTCTTTACAAGAAGCGGCGCTGTCAATATTCCCATCAACTT
GAAGGCATCAAAAGATCTCGGATTAAATGAAGAAAGTTATGCGATCTCAATTCCGCTTGGTGGCTCGGCAAATTCTGGTG
GCGCAGCGATTACAGTGTCGATCATGACGTTGGCAACCGCCAATACCATGGGGGTACATGTCAGCATTTTCCTAGCCTTG
TTGCTATGTTTCTTGTCTGCCATCTCGGCTACCGGGGTTTCCGGGATCGCAGGTGGCTCACTGTTGTTAATTCCAATGGC
GGCTTCATTGTTTGGCATTTCAAATGATATTGCCATGCAGGTTGTCGGTATCGGTTTTATCATCGGCGTGGTTCAAGATT
CAGTTGAAACGGCTGTTAACTCCGCGTCTGACTTGCTGTTCACCGCGACTGCCGAGTATGCCGACGATCGCCGTGAAGGA
CATCCGGTTGATATTCGAGCTAAGGTCAAAGCGGCAGGCAAGGGAACGGCAGAAGTTGTCACACCTGAAAAGGCCAATGA
AGCTGAAGAAAGTGAACAAGTTTAG

Upstream 100 bases:

>100_bases
TGATCCTATTTGAATTAAATTGCTTGCAGTTGTTGTAAAAATAAGGCAAACTAAGAAGTGCTCTCATGGAAAGTTAATTT
TAGATGAAGGAGGGGCCAAG

Downstream 100 bases:

>100_bases
TTTGATAAAAAGAATCGCGATTTTTTCGCGATTCTTTTTATGTCCGGCTAATTTGAGACAAAATGATAACAAGTGTCTTT
AAACTCACATTGGACAATAA

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MYKRYKDVSLILKIVIGIIVGAVLGVMVPSWSFIDVLGKLFVGALKAIAPLLVFLLIMSAISKYRSGAKNHFGTVIVLYL
SATLFSSIAAVAVSYLFPIKLVLPGAMKIAESAPKDLGTVVTSLLTNAVANPISALVEGNYLAILFWSLLIGSGLRLTSA
VTKKVVTELADTVSAVAQNVIQFAPFGIVGLLHESLSKTGVKGVMAYGQLLMLLVATMVFVYLVVYPFMVWLMTRQNPYP
LTFWTLKVSGIPAFFTRSGAVNIPINLKASKDLGLNEESYAISIPLGGSANSGGAAITVSIMTLATANTMGVHVSIFLAL
LLCFLSAISATGVSGIAGGSLLLIPMAASLFGISNDIAMQVVGIGFIIGVVQDSVETAVNSASDLLFTATAEYADDRREG
HPVDIRAKVKAAGKGTAEVVTPEKANEAEESEQV

Sequences:

>Translated_434_residues
MYKRYKDVSLILKIVIGIIVGAVLGVMVPSWSFIDVLGKLFVGALKAIAPLLVFLLIMSAISKYRSGAKNHFGTVIVLYL
SATLFSSIAAVAVSYLFPIKLVLPGAMKIAESAPKDLGTVVTSLLTNAVANPISALVEGNYLAILFWSLLIGSGLRLTSA
VTKKVVTELADTVSAVAQNVIQFAPFGIVGLLHESLSKTGVKGVMAYGQLLMLLVATMVFVYLVVYPFMVWLMTRQNPYP
LTFWTLKVSGIPAFFTRSGAVNIPINLKASKDLGLNEESYAISIPLGGSANSGGAAITVSIMTLATANTMGVHVSIFLAL
LLCFLSAISATGVSGIAGGSLLLIPMAASLFGISNDIAMQVVGIGFIIGVVQDSVETAVNSASDLLFTATAEYADDRREG
HPVDIRAKVKAAGKGTAEVVTPEKANEAEESEQV
>Mature_434_residues
MYKRYKDVSLILKIVIGIIVGAVLGVMVPSWSFIDVLGKLFVGALKAIAPLLVFLLIMSAISKYRSGAKNHFGTVIVLYL
SATLFSSIAAVAVSYLFPIKLVLPGAMKIAESAPKDLGTVVTSLLTNAVANPISALVEGNYLAILFWSLLIGSGLRLTSA
VTKKVVTELADTVSAVAQNVIQFAPFGIVGLLHESLSKTGVKGVMAYGQLLMLLVATMVFVYLVVYPFMVWLMTRQNPYP
LTFWTLKVSGIPAFFTRSGAVNIPINLKASKDLGLNEESYAISIPLGGSANSGGAAITVSIMTLATANTMGVHVSIFLAL
LLCFLSAISATGVSGIAGGSLLLIPMAASLFGISNDIAMQVVGIGFIIGVVQDSVETAVNSASDLLFTATAEYADDRREG
HPVDIRAKVKAAGKGTAEVVTPEKANEAEESEQV

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Escherichia coli, GI1789473, Length=370, Percent_Identity=47.027027027027, Blast_Score=340, Evalue=9e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_LACC3 (Q03BE8)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_805916.1
- ProteinModelPortal:   Q03BE8
- SMR:   Q03BE8
- STRING:   Q03BE8
- GeneID:   4419184
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_0632
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   FSHEAAK
- PhylomeDB:   Q03BE8
- ProtClustDB:   PRK13628
- BioCyc:   LCAS321967:LSEI_0632-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 45611; Mature: 45611

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x133fefc0)-; HASH(0x1480184c)-; HASH(0x142dbdb8)-; HASH(0x1482ca7c)-; HASH(0x12e92fbc)-; HASH(0x13beb0a8)-; HASH(0x14005d24)-; HASH(0x13e1dba4)-; HASH(0x144270b4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCHHCCCH
>Mature Secondary Structure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CCCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA