Click here to switch to the map view.

The map label for this gene is oxaA

Identifier: 116493571

GI number: 116493571

Start: 1830462

End: 1831301

Strand: Reverse

Name: oxaA

Synonym: PEPE_1845

Alternate gene names: 116493571

Gene position: 1831301-1830462 (Counterclockwise)

Preceding gene: 116493572

Following gene: 116493570

Centisome position: 99.94

GC content: 39.29

Gene sequence:

>840_bases
GTGAAACATTTAAAACGAAATATGGCGTTGCTCAGTGTGGCAGCCCTATCCTTCATATTAACTGCGTGTAGCACAGCGCC
CATCACCAGTCACAGTACTGGGATTTGGGACGGAGTGATTGTTTACAATTTCTCGAGATTCATCATCTACTTATCCAAGT
TGTTTGGTGGCAATTATGGTTGGGGTATTATTGTTTTCACCATAATAATTCGAATTATCATCTTACCATTGATGATTTAT
CAAACTAGAACAACGATGAAAACAGCTGAACTTCAACCCAAGTTAAAACAGTTACAGCAAAAATATTCATCACGAGATGC
TGAAAGTCAGCAAAAACTTCGTGAAGAACAGCAAAAGCTTTATGCTGAAGCTGGGGTAAATCCGATGGCTGGATGTTTGC
CATTGATCATCCAATTACCAGTTATGTATGCTTTGTATGCGGCGGTTAGCCGGACCCAAGTGTTAAAAGAGGGTACTTTC
TTATGGCTACAATTGAGTGATAAGGATCCTTACTTTATTTTACCCATCTTAGCCGCCTTGTTCACATTTATGAGTACTTG
GTTGTCGATGAAGTCACAACCCGCTGGATCACAAAATGGAATGACATCGGCCATGACGTTTGGTATGCCACTAGTAATTT
TGATTACTGCTTTAAACTTCCCAGCAGCGATCACATTGTACTGGGTAGTAACTAACCTATTCCAAGTTGGTCAAACACTT
ATAATTCAGAATCCGTTCAAGATCCAAAAAGAACGTGAAGAAAAAATTCAAACTGAAAAGGCAAAGCGTAAAGCAATTGA
AAAAGCTAAACGCCGAGCAATGAAGAGTAAACGAAAATAA

Upstream 100 bases:

>100_bases
CACAAGCTTCTGGACTACCAATGAATGAAGTTAAACAACAATTGGAACATGTTTTTAAGCTAGCAGGGTTGTTTGCTTCA
AAACAAAGTGAGGAAGAATA

Downstream 100 bases:

>100_bases
TTTATGAAAGCAATCGCAACTGTTTCGCAGGGGTGATTGCTTTTTTGATGGACTAAATGCAGGTTGATTTAAGTAACGTG
ATGATGGAGTGATATGATGC

Product: preprotein translocase subunit YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKHLKRNMALLSVAALSFILTACSTAPITSHSTGIWDGVIVYNFSRFIIYLSKLFGGNYGWGIIVFTIIIRIIILPLMIY
QTRTTMKTAELQPKLKQLQQKYSSRDAESQQKLREEQQKLYAEAGVNPMAGCLPLIIQLPVMYALYAAVSRTQVLKEGTF
LWLQLSDKDPYFILPILAALFTFMSTWLSMKSQPAGSQNGMTSAMTFGMPLVILITALNFPAAITLYWVVTNLFQVGQTL
IIQNPFKIQKEREEKIQTEKAKRKAIEKAKRRAMKSKRK

Sequences:

>Translated_279_residues
MKHLKRNMALLSVAALSFILTACSTAPITSHSTGIWDGVIVYNFSRFIIYLSKLFGGNYGWGIIVFTIIIRIIILPLMIY
QTRTTMKTAELQPKLKQLQQKYSSRDAESQQKLREEQQKLYAEAGVNPMAGCLPLIIQLPVMYALYAAVSRTQVLKEGTF
LWLQLSDKDPYFILPILAALFTFMSTWLSMKSQPAGSQNGMTSAMTFGMPLVILITALNFPAAITLYWVVTNLFQVGQTL
IIQNPFKIQKEREEKIQTEKAKRKAIEKAKRRAMKSKRK
>Mature_279_residues
MKHLKRNMALLSVAALSFILTACSTAPITSHSTGIWDGVIVYNFSRFIIYLSKLFGGNYGWGIIVFTIIIRIIILPLMIY
QTRTTMKTAELQPKLKQLQQKYSSRDAESQQKLREEQQKLYAEAGVNPMAGCLPLIIQLPVMYALYAAVSRTQVLKEGTF
LWLQLSDKDPYFILPILAALFTFMSTWLSMKSQPAGSQNGMTSAMTFGMPLVILITALNFPAAITLYWVVTNLFQVGQTL
IIQNPFKIQKEREEKIQTEKAKRKAIEKAKRRAMKSKRK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=190, Percent_Identity=34.7368421052632, Blast_Score=112, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24662345, Length=208, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21356443, Length=208, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_PEDPA (Q03D58)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_805306.1
- STRING:   Q03D58
- GeneID:   4417374
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1845
- NMPDR:   fig|278197.10.peg.1635
- eggNOG:   COG0706
- HOGENOM:   HBG560622
- OMA:   MKSAPER
- ProtClustDB:   CLSK821543
- BioCyc:   PPEN278197:PEPE_1845-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 31668; Mature: 31668

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1919c6b0)-; HASH(0x192b0250)-; HASH(0x19041824)-; HASH(0x1791d3c8)-; HASH(0x192fe504)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA