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The map label for this gene is bglA [H]

Identifier: 116493504

GI number: 116493504

Start: 1751331

End: 1752713

Strand: Reverse

Name: bglA [H]

Synonym: PEPE_1776

Alternate gene names: 116493504

Gene position: 1752713-1751331 (Counterclockwise)

Preceding gene: 116493506

Following gene: 116493503

Centisome position: 95.65

GC content: 38.39

Gene sequence:

>1383_bases
TTGAAAGGAAAACTACCAGATAATTTTTTATGGGGAAACTCAACATCAAGCATGCAGACAGAAGGAGGTGTTCATGAAGG
CGGTAAGGGACCATCAGTTTATGATACATATGAAGCAACCGAAACTACCTCAAACTGGGATGTTGCTATTGATAATTACC
ATCATTATGAGGAAGACCTAGATTTGATGGCTAATCAAGGAATGAATTGTTATCGTTTCCAAATTTCATGGAGTCGTGTA
AACCCTACCGGAGATGGGGATTTTAATGAAGAAGGTATCCAATATTATGACAGATTAATTAATGATTTACTGAAACGTGG
AATCAAGCCGATGATTTGCCTGTATCATTTCGATATGCCATTACATTTAGCGGAAAAATACAACGGCTTCATGAGTCGCC
ACGTGGTTGACGCATTTGTGCGTTTTGGTAAGAAAATGGTGGATTGCTTTAGCGATCGTGTGAAACTATGGGTAACTTTT
AATGAACAAAACTTATATTCACAGACAGAAGCTTTCCACATTGCAGGCTATTTGAAAGGTGACCAAACTGACGAAGAACT
CCAGTTAATTGCTCATCACGTAATGACCGCCCATGCCCAAGTCGCTAATTATGTGCACGAAACTAGTGATGCTCAAATTG
GAGGGATGTTAGCATATGTGGAATCTTATCCTAAAAATTGTCGTCCGCGTGATGTTTATGTGGCCCGCCAAATTGATGAA
TTTTTGAATCGTAATTTATTGGAGGCTTGGGTACACGGCCACTACTCGACTGAGGTTACCCAGTATATCAAGAATCATCA
TTTTGATATCGATTTTACAGAACAAGATCAAATAGCATTTGAAAAATTGAAGAGTGATTTTATTTCGTTTAGTTATTATG
CAAGTAACGTTGTTGATTCAACCAAAATTCCACAGGGAACGATGCCTAATCGTTATCTAGATTATGGAGGGGTCGAAAAT
CCATATTTAAAGGCTACAGATTGGGGATGGAACATTGATCCATTAGGATTCCGTGATGTTATCACTAAGACTTACAACGA
ATACGGTATTCCCATGTTTCCAATTGAAAATGGTATCGGTTATCGTGAAAAATTCGATGGGACAGAGATTCAAGATGATT
ACCGAATTGAATATCATCGTGACCATATCCAAGCGATGATTGATGCGGTTGTGGAAGATGGTGTCCCAGTCTTAGGTTAT
CTTGGTTGGGGATTAATCGACATTCCTAGTTCTTCTGGAAATATGGAAAAACGCTATGGGATGGTGTACGTAAATCGTGG
CAACCACGAGTTACGTGATATGAAACGGGTCCCTAAGAAGAGTTATAAATGGTTTAAAAAAGTTATTGAAACTAATGGGA
ACGATTTAGAAAATGATCTTTAA

Upstream 100 bases:

>100_bases
ACAATTTTTATAAAAGTATAGTCTTTTAAAATAAAAGTATTTACTTAAATAAAAAATAAAGCTATAATGAAAGCGAATTC
AATTAGAGAGGAGCGTTATT

Downstream 100 bases:

>100_bases
TGGGAGGATTTAAAATGGGTAGTTCGAACAAAGAATCAGTCAATGATAAGATGCAAAATTCTAAATTCATTGCTAAGTTC
ACTGAAATCTCAGTTAAAGT

Product: Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKGKLPDNFLWGNSTSSMQTEGGVHEGGKGPSVYDTYEATETTSNWDVAIDNYHHYEEDLDLMANQGMNCYRFQISWSRV
NPTGDGDFNEEGIQYYDRLINDLLKRGIKPMICLYHFDMPLHLAEKYNGFMSRHVVDAFVRFGKKMVDCFSDRVKLWVTF
NEQNLYSQTEAFHIAGYLKGDQTDEELQLIAHHVMTAHAQVANYVHETSDAQIGGMLAYVESYPKNCRPRDVYVARQIDE
FLNRNLLEAWVHGHYSTEVTQYIKNHHFDIDFTEQDQIAFEKLKSDFISFSYYASNVVDSTKIPQGTMPNRYLDYGGVEN
PYLKATDWGWNIDPLGFRDVITKTYNEYGIPMFPIENGIGYREKFDGTEIQDDYRIEYHRDHIQAMIDAVVEDGVPVLGY
LGWGLIDIPSSSGNMEKRYGMVYVNRGNHELRDMKRVPKKSYKWFKKVIETNGNDLENDL

Sequences:

>Translated_460_residues
MKGKLPDNFLWGNSTSSMQTEGGVHEGGKGPSVYDTYEATETTSNWDVAIDNYHHYEEDLDLMANQGMNCYRFQISWSRV
NPTGDGDFNEEGIQYYDRLINDLLKRGIKPMICLYHFDMPLHLAEKYNGFMSRHVVDAFVRFGKKMVDCFSDRVKLWVTF
NEQNLYSQTEAFHIAGYLKGDQTDEELQLIAHHVMTAHAQVANYVHETSDAQIGGMLAYVESYPKNCRPRDVYVARQIDE
FLNRNLLEAWVHGHYSTEVTQYIKNHHFDIDFTEQDQIAFEKLKSDFISFSYYASNVVDSTKIPQGTMPNRYLDYGGVEN
PYLKATDWGWNIDPLGFRDVITKTYNEYGIPMFPIENGIGYREKFDGTEIQDDYRIEYHRDHIQAMIDAVVEDGVPVLGY
LGWGLIDIPSSSGNMEKRYGMVYVNRGNHELRDMKRVPKKSYKWFKKVIETNGNDLENDL
>Mature_460_residues
MKGKLPDNFLWGNSTSSMQTEGGVHEGGKGPSVYDTYEATETTSNWDVAIDNYHHYEEDLDLMANQGMNCYRFQISWSRV
NPTGDGDFNEEGIQYYDRLINDLLKRGIKPMICLYHFDMPLHLAEKYNGFMSRHVVDAFVRFGKKMVDCFSDRVKLWVTF
NEQNLYSQTEAFHIAGYLKGDQTDEELQLIAHHVMTAHAQVANYVHETSDAQIGGMLAYVESYPKNCRPRDVYVARQIDE
FLNRNLLEAWVHGHYSTEVTQYIKNHHFDIDFTEQDQIAFEKLKSDFISFSYYASNVVDSTKIPQGTMPNRYLDYGGVEN
PYLKATDWGWNIDPLGFRDVITKTYNEYGIPMFPIENGIGYREKFDGTEIQDDYRIEYHRDHIQAMIDAVVEDGVPVLGY
LGWGLIDIPSSSGNMEKRYGMVYVNRGNHELRDMKRVPKKSYKWFKKVIETNGNDLENDL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=485, Percent_Identity=29.2783505154639, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI32481206, Length=486, Percent_Identity=29.2181069958848, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI13273313, Length=474, Percent_Identity=28.4810126582279, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI28376633, Length=475, Percent_Identity=26.9473684210526, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI24497614, Length=485, Percent_Identity=27.6288659793814, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI190360571, Length=96, Percent_Identity=39.5833333333333, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI2367174, Length=481, Percent_Identity=37.4220374220374, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1789070, Length=479, Percent_Identity=36.5344467640919, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=35.7142857142857, Blast_Score=289, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17539390, Length=476, Percent_Identity=26.0504201680672, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17552856, Length=473, Percent_Identity=26.6384778012685, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356577, Length=493, Percent_Identity=27.3833671399594, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53348; Mature: 53348

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKLPDNFLWGNSTSSMQTEGGVHEGGKGPSVYDTYEATETTSNWDVAIDNYHHYEEDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEECCCHHHHHHH
DLMANQGMNCYRFQISWSRVNPTGDGDFNEEGIQYYDRLINDLLKRGIKPMICLYHFDMP
HHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
LHLAEKYNGFMSRHVVDAFVRFGKKMVDCFSDRVKLWVTFNEQNLYSQTEAFHIAGYLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHEEEEEEECC
DQTDEELQLIAHHVMTAHAQVANYVHETSDAQIGGMLAYVESYPKNCRPRDVYVARQIDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FLNRNLLEAWVHGHYSTEVTQYIKNHHFDIDFTEQDQIAFEKLKSDFISFSYYASNVVDS
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TKIPQGTMPNRYLDYGGVENPYLKATDWGWNIDPLGFRDVITKTYNEYGIPMFPIENGIG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCC
YREKFDGTEIQDDYRIEYHRDHIQAMIDAVVEDGVPVLGYLGWGLIDIPSSSGNMEKRYG
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHCCCEEECCCCCCCCCHHCC
MVYVNRGNHELRDMKRVPKKSYKWFKKVIETNGNDLENDL
EEEEECCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKGKLPDNFLWGNSTSSMQTEGGVHEGGKGPSVYDTYEATETTSNWDVAIDNYHHYEEDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEECCCHHHHHHH
DLMANQGMNCYRFQISWSRVNPTGDGDFNEEGIQYYDRLINDLLKRGIKPMICLYHFDMP
HHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
LHLAEKYNGFMSRHVVDAFVRFGKKMVDCFSDRVKLWVTFNEQNLYSQTEAFHIAGYLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHEEEEEEECC
DQTDEELQLIAHHVMTAHAQVANYVHETSDAQIGGMLAYVESYPKNCRPRDVYVARQIDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FLNRNLLEAWVHGHYSTEVTQYIKNHHFDIDFTEQDQIAFEKLKSDFISFSYYASNVVDS
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TKIPQGTMPNRYLDYGGVENPYLKATDWGWNIDPLGFRDVITKTYNEYGIPMFPIENGIG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCC
YREKFDGTEIQDDYRIEYHRDHIQAMIDAVVEDGVPVLGYLGWGLIDIPSSSGNMEKRYG
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHCCCEEECCCCCCCCCHHCC
MVYVNRGNHELRDMKRVPKKSYKWFKKVIETNGNDLENDL
EEEEECCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]