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The map label for this gene is gmuC [H]

Identifier: 116493503

GI number: 116493503

Start: 1749973

End: 1751316

Strand: Reverse

Name: gmuC [H]

Synonym: PEPE_1775

Alternate gene names: 116493503

Gene position: 1751316-1749973 (Counterclockwise)

Preceding gene: 116493504

Following gene: 116493502

Centisome position: 95.58

GC content: 37.28

Gene sequence:

>1344_bases
ATGGGTAGTTCGAACAAAGAATCAGTCAATGATAAGATGCAAAATTCTAAATTCATTGCTAAGTTCACTGAAATCTCAGT
TAAAGTCGGAAACTGGGTATATCTCCGTTCACTCCGTGATGCTTTTGCCGTCATTTTACCAATGTTTATTGTAGCCGGAA
TTGGGGTATTGTTAAATAACGTTGTCTTTACCTGGTTTTTGAGTGGGGATATGCTGACAAAATTCCAAGTGATTGGAAAC
GCCATTGTTAATGGGACGTTAAATGTAGCCGGAATTTTAGTTGCGCCAATGATCGGTTATAGTCTTGCTCGTAATAAAGG
CTTTAATAATCCAATTGCGGCTGCTGCGATGTCTTTAGCAAGTATTTTCATCCTAATGCCAGGAAGCATTCAGTTAGGAA
CGGTTGCTTCAGCAGGGGCAAAAATGGCGACGGTCACAGGTGGACTTAGTTATTTGAATACGGGAACGCAAGGAATGTTT
GGTGGGATTTTTGTTGGGCTGATTGCAACCGGCCTCTTTATCAAACTTGCCTCGATTAAAAAATTACAAATTCACTTAGG
GGAAAATGTACCACCAGCAGTTTCTGCTTCATTTAGTGTTTTAATTCCAGCCATTTTATTAATGTCGTTTTTTGCTATTA
TTGCAGCGTTGCTGGCAGGATTTTTCAACACCGATTTAATCAACTTAATTAAAACTTGGATCCAAGAACCTTTACGAGGC
TTTAATACAAGTATTGTGGGTTACTGTGTAATTTATACTTTAGCTAATTTCCTTTTTGGTTTAGGTATTCATCAAACCGT
ATTATCAGGTGCATTGCTTGATCCCCTTGTATTAGTTAATATGAACGAAAACATGACTGCTTATGCACATCACCAAGCCA
TTCCAAATATTATTACAACTTCATTTGTAAGTAATTACACCTTAATCGGTGGTTCAGGTAGTACGATTGCGTTGATTATT
GCTATTTTAATTTTTAGTAAAGCTAAATCTTCTCGTCAAATTGCTGGATTATCGTTGGCACCAGGAATCTTTAATATTAA
TGAACCGATGATTTTTGGTTTTCCAATTGTCTTTAATTTACCTTTGATTATTCCATTTGTTTTATTCCCAGTTGTTGGGA
GTTTGATGGGTTACTTTGCTACACTTTGGGGCTGGGTCAGTCGAACAGTAGTATTAGTACCATGGACAACTCCTCCTTTG
ATCGGACCATATCTTTCAACAGCCGGAGACTGGCGCGCAGTTATTTTACAAATCTTAATTATTGTGGTCGGAGTATTCTT
ATACTTACCATTCTTGAAGATTAGTGAACGTGTTTCTGAAATTCAAGCTGAAGAAAATCTATAA

Upstream 100 bases:

>100_bases
ATATGAAACGGGTCCCTAAGAAGAGTTATAAATGGTTTAAAAAAGTTATTGAAACTAATGGGAACGATTTAGAAAATGAT
CTTTAATGGGAGGATTTAAA

Downstream 100 bases:

>100_bases
TTGGTCAAAAAATCAAAACCTCAAACTAATTATCAGAATTAGTTTGAGGTTTTTTAGTCTTTCGAAGCTAGTCTTTTTAT
CTTATAAAAATTAACAACTT

Product: cellobiose-specific PTS system IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MGSSNKESVNDKMQNSKFIAKFTEISVKVGNWVYLRSLRDAFAVILPMFIVAGIGVLLNNVVFTWFLSGDMLTKFQVIGN
AIVNGTLNVAGILVAPMIGYSLARNKGFNNPIAAAAMSLASIFILMPGSIQLGTVASAGAKMATVTGGLSYLNTGTQGMF
GGIFVGLIATGLFIKLASIKKLQIHLGENVPPAVSASFSVLIPAILLMSFFAIIAALLAGFFNTDLINLIKTWIQEPLRG
FNTSIVGYCVIYTLANFLFGLGIHQTVLSGALLDPLVLVNMNENMTAYAHHQAIPNIITTSFVSNYTLIGGSGSTIALII
AILIFSKAKSSRQIAGLSLAPGIFNINEPMIFGFPIVFNLPLIIPFVLFPVVGSLMGYFATLWGWVSRTVVLVPWTTPPL
IGPYLSTAGDWRAVILQILIIVVGVFLYLPFLKISERVSEIQAEENL

Sequences:

>Translated_447_residues
MGSSNKESVNDKMQNSKFIAKFTEISVKVGNWVYLRSLRDAFAVILPMFIVAGIGVLLNNVVFTWFLSGDMLTKFQVIGN
AIVNGTLNVAGILVAPMIGYSLARNKGFNNPIAAAAMSLASIFILMPGSIQLGTVASAGAKMATVTGGLSYLNTGTQGMF
GGIFVGLIATGLFIKLASIKKLQIHLGENVPPAVSASFSVLIPAILLMSFFAIIAALLAGFFNTDLINLIKTWIQEPLRG
FNTSIVGYCVIYTLANFLFGLGIHQTVLSGALLDPLVLVNMNENMTAYAHHQAIPNIITTSFVSNYTLIGGSGSTIALII
AILIFSKAKSSRQIAGLSLAPGIFNINEPMIFGFPIVFNLPLIIPFVLFPVVGSLMGYFATLWGWVSRTVVLVPWTTPPL
IGPYLSTAGDWRAVILQILIIVVGVFLYLPFLKISERVSEIQAEENL
>Mature_446_residues
GSSNKESVNDKMQNSKFIAKFTEISVKVGNWVYLRSLRDAFAVILPMFIVAGIGVLLNNVVFTWFLSGDMLTKFQVIGNA
IVNGTLNVAGILVAPMIGYSLARNKGFNNPIAAAAMSLASIFILMPGSIQLGTVASAGAKMATVTGGLSYLNTGTQGMFG
GIFVGLIATGLFIKLASIKKLQIHLGENVPPAVSASFSVLIPAILLMSFFAIIAALLAGFFNTDLINLIKTWIQEPLRGF
NTSIVGYCVIYTLANFLFGLGIHQTVLSGALLDPLVLVNMNENMTAYAHHQAIPNIITTSFVSNYTLIGGSGSTIALIIA
ILIFSKAKSSRQIAGLSLAPGIFNINEPMIFGFPIVFNLPLIIPFVLFPVVGSLMGYFATLWGWVSRTVVLVPWTTPPLI
GPYLSTAGDWRAVILQILIIVVGVFLYLPFLKISERVSEIQAEENL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=454, Percent_Identity=27.5330396475771, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47977; Mature: 47846

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSNKESVNDKMQNSKFIAKFTEISVKVGNWVYLRSLRDAFAVILPMFIVAGIGVLLNN
CCCCCCHHHHHHHHCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFTWFLSGDMLTKFQVIGNAIVNGTLNVAGILVAPMIGYSLARNKGFNNPIAAAAMSLA
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SIFILMPGSIQLGTVASAGAKMATVTGGLSYLNTGTQGMFGGIFVGLIATGLFIKLASIK
HHHHCCCCCEEECCHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLQIHLGENVPPAVSASFSVLIPAILLMSFFAIIAALLAGFFNTDLINLIKTWIQEPLRG
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNTSIVGYCVIYTLANFLFGLGIHQTVLSGALLDPLVLVNMNENMTAYAHHQAIPNIITT
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHH
SFVSNYTLIGGSGSTIALIIAILIFSKAKSSRQIAGLSLAPGIFNINEPMIFGFPIVFNL
HHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCEECCCCEEECCHHHHHH
PLIIPFVLFPVVGSLMGYFATLWGWVSRTVVLVPWTTPPLIGPYLSTAGDWRAVILQILI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHH
IVVGVFLYLPFLKISERVSEIQAEENL
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSSNKESVNDKMQNSKFIAKFTEISVKVGNWVYLRSLRDAFAVILPMFIVAGIGVLLNN
CCCCCHHHHHHHHCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFTWFLSGDMLTKFQVIGNAIVNGTLNVAGILVAPMIGYSLARNKGFNNPIAAAAMSLA
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SIFILMPGSIQLGTVASAGAKMATVTGGLSYLNTGTQGMFGGIFVGLIATGLFIKLASIK
HHHHCCCCCEEECCHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLQIHLGENVPPAVSASFSVLIPAILLMSFFAIIAALLAGFFNTDLINLIKTWIQEPLRG
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNTSIVGYCVIYTLANFLFGLGIHQTVLSGALLDPLVLVNMNENMTAYAHHQAIPNIITT
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHH
SFVSNYTLIGGSGSTIALIIAILIFSKAKSSRQIAGLSLAPGIFNINEPMIFGFPIVFNL
HHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCEECCCCEEECCHHHHHH
PLIIPFVLFPVVGSLMGYFATLWGWVSRTVVLVPWTTPPLIGPYLSTAGDWRAVILQILI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHH
IVVGVFLYLPFLKISERVSEIQAEENL
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]