Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 116493449

GI number: 116493449

Start: 1697416

End: 1698522

Strand: Reverse

Name: engD [H]

Synonym: PEPE_1721

Alternate gene names: 116493449

Gene position: 1698522-1697416 (Counterclockwise)

Preceding gene: 116493450

Following gene: 116493448

Centisome position: 92.69

GC content: 41.46

Gene sequence:

>1107_bases
ATGGCATTAACAGCTGGTATTGTTGGACTTCCGAACGTCGGTAAGTCAACGTTATTTAACGCAATTACAAAGGCGGGAGC
CGAAATGGCTAACTATCCGTTTGCTACAATCGATCCAAACGTCGGGATGGTAGAAGTACCAGATCAACGTTTAGATCGGA
TTCAAGAAATTATCCCTGCTAAAAAGATTGTGCACACAACCTTTGAATTTACCGATATTGCAGGGATTGTTAAGGGTGCA
AGTAAGGGTGAAGGACTTGGAAATAAATTTCTTGAAAATATTCGCCAAGTGGATGCAATTGTTCACGTTGTTCGAGCCTT
TGACGACGACAATATCACAACTGTTTCAGGTAAAGTTGACCCCATCGAAGATATCGAAACCATCAACTTGGAATTGAGTC
TAGCTGACTTGGAAAGTGTCGAAAAACGTTTGACTAAGGTACAGCGTGCGGCTAAGGGACGCGATAAAGATGCAGTAGCA
GAATTAGCGGTACTGGAAAAATTACATCCAGTTTTGGAAGCTGGTAAAGCAGCCCGTACAATCGATTTTGATGAATCAGA
AATGCCTATTGTTAAAGGACTTTTCTTGCTAACTACTAAGCCCGTACTTTATGTGGCTAATATTGCAGAGGACGATATGG
CCGATCCTGAAGCTTCCAAGTACTTCAAAGAAATTAAAGATTATGTTGCTCAAGAAGACCCTGATGCGCAAGTTTTGGGT
ATTTCAGCTGAAACTGAACAAGAAATCGCTGAATTAGAAGATGACGAAAAAGCGGAATTTCTTGAAGCAGAAGGAATTAC
TGAACCAGGCTTAAACCGTCTAATTCAAGCCTCATACAACCTTTTAGGTCTTCAAACCTTCTTCACGGCGGGTGGAAAAG
AAACACGGGCATGGACGTTTAAGAAGGGAATGACGGCTCCTCAAACAGCTGGTGTAATTCATTCTGATTTTGAACGTGGA
TTTATTCGTGCTGAAACAGTTTCATTTGATGATTTAGACAAGTATGGCAGTATGCAAGGTGTTCGTGAAGCGGGACGTTT
ACGTCTTGAAGGTAAGGAATACCTTGTGCAAGATGGCGATATTATCGAATTCCGCTTTAATGTCTAA

Upstream 100 bases:

>100_bases
TGAAAGCGCAACTTTGGCTCTGAACGGTCTGTTAACGACCCCTAATTTTTGATAATATATAGAGAAGAACACGCAGTTTT
GAAAGGAAAGTGGAATTAAA

Downstream 100 bases:

>100_bases
TATAAATCAAACGAGGAGTAAATAGATTATGACTGAAGAACCACGTAATGAGGGCAAGCAAAGTAGTTCAGTTGCCCACC
ATGAAAATGAACCTAAAAAA

Product: GTPase, translation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEMANYPFATIDPNVGMVEVPDQRLDRIQEIIPAKKIVHTTFEFTDIAGIVKGA
SKGEGLGNKFLENIRQVDAIVHVVRAFDDDNITTVSGKVDPIEDIETINLELSLADLESVEKRLTKVQRAAKGRDKDAVA
ELAVLEKLHPVLEAGKAARTIDFDESEMPIVKGLFLLTTKPVLYVANIAEDDMADPEASKYFKEIKDYVAQEDPDAQVLG
ISAETEQEIAELEDDEKAEFLEAEGITEPGLNRLIQASYNLLGLQTFFTAGGKETRAWTFKKGMTAPQTAGVIHSDFERG
FIRAETVSFDDLDKYGSMQGVREAGRLRLEGKEYLVQDGDIIEFRFNV

Sequences:

>Translated_368_residues
MALTAGIVGLPNVGKSTLFNAITKAGAEMANYPFATIDPNVGMVEVPDQRLDRIQEIIPAKKIVHTTFEFTDIAGIVKGA
SKGEGLGNKFLENIRQVDAIVHVVRAFDDDNITTVSGKVDPIEDIETINLELSLADLESVEKRLTKVQRAAKGRDKDAVA
ELAVLEKLHPVLEAGKAARTIDFDESEMPIVKGLFLLTTKPVLYVANIAEDDMADPEASKYFKEIKDYVAQEDPDAQVLG
ISAETEQEIAELEDDEKAEFLEAEGITEPGLNRLIQASYNLLGLQTFFTAGGKETRAWTFKKGMTAPQTAGVIHSDFERG
FIRAETVSFDDLDKYGSMQGVREAGRLRLEGKEYLVQDGDIIEFRFNV
>Mature_367_residues
ALTAGIVGLPNVGKSTLFNAITKAGAEMANYPFATIDPNVGMVEVPDQRLDRIQEIIPAKKIVHTTFEFTDIAGIVKGAS
KGEGLGNKFLENIRQVDAIVHVVRAFDDDNITTVSGKVDPIEDIETINLELSLADLESVEKRLTKVQRAAKGRDKDAVAE
LAVLEKLHPVLEAGKAARTIDFDESEMPIVKGLFLLTTKPVLYVANIAEDDMADPEASKYFKEIKDYVAQEDPDAQVLGI
SAETEQEIAELEDDEKAEFLEAEGITEPGLNRLIQASYNLLGLQTFFTAGGKETRAWTFKKGMTAPQTAGVIHSDFERGF
IRAETVSFDDLDKYGSMQGVREAGRLRLEGKEYLVQDGDIIEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=44.3243243243243, Blast_Score=302, Evalue=4e-82,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=39.2070484581498, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI24308117, Length=100, Percent_Identity=37, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1787454, Length=368, Percent_Identity=55.7065217391304, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=30.7086614173228, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=367, Percent_Identity=41.1444141689373, Blast_Score=287, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI17508313, Length=101, Percent_Identity=34.6534653465347, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=377, Percent_Identity=40.5835543766578, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=36.2204724409449, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=157, Percent_Identity=38.2165605095541, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321962, Length=172, Percent_Identity=28.4883720930233, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=40.5994550408719, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=40.5994550408719, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=40.5994550408719, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=38.6503067484663, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24585318, Length=137, Percent_Identity=32.1167883211679, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40458; Mature: 40327

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTAGIVGLPNVGKSTLFNAITKAGAEMANYPFATIDPNVGMVEVPDQRLDRIQEIIPA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCHHHHHHHHHHHHH
KKIVHTTFEFTDIAGIVKGASKGEGLGNKFLENIRQVDAIVHVVRAFDDDNITTVSGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PIEDIETINLELSLADLESVEKRLTKVQRAAKGRDKDAVAELAVLEKLHPVLEAGKAART
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
IDFDESEMPIVKGLFLLTTKPVLYVANIAEDDMADPEASKYFKEIKDYVAQEDPDAQVLG
ECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
ISAETEQEIAELEDDEKAEFLEAEGITEPGLNRLIQASYNLLGLQTFFTAGGKETRAWTF
CCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
KKGMTAPQTAGVIHSDFERGFIRAETVSFDDLDKYGSMQGVREAGRLRLEGKEYLVQDGD
CCCCCCCCCCCCHHHHHHCCCEEEEECCHHHHHHHCCHHHHHHHCCEEECCCHHEECCCC
IIEFRFNV
EEEEEECC
>Mature Secondary Structure 
ALTAGIVGLPNVGKSTLFNAITKAGAEMANYPFATIDPNVGMVEVPDQRLDRIQEIIPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCHHHHHHHHHHHHH
KKIVHTTFEFTDIAGIVKGASKGEGLGNKFLENIRQVDAIVHVVRAFDDDNITTVSGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PIEDIETINLELSLADLESVEKRLTKVQRAAKGRDKDAVAELAVLEKLHPVLEAGKAART
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
IDFDESEMPIVKGLFLLTTKPVLYVANIAEDDMADPEASKYFKEIKDYVAQEDPDAQVLG
ECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
ISAETEQEIAELEDDEKAEFLEAEGITEPGLNRLIQASYNLLGLQTFFTAGGKETRAWTF
CCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
KKGMTAPQTAGVIHSDFERGFIRAETVSFDDLDKYGSMQGVREAGRLRLEGKEYLVQDGD
CCCCCCCCCCCCHHHHHHCCCEEEEECCHHHHHHHCCHHHHHHHCCEEECCCHHEECCCC
IIEFRFNV
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]