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The map label for this gene is mntH

Identifier: 116493429

GI number: 116493429

Start: 1675896

End: 1677239

Strand: Reverse

Name: mntH

Synonym: PEPE_1701

Alternate gene names: 116493429

Gene position: 1677239-1675896 (Counterclockwise)

Preceding gene: 116493430

Following gene: 116493428

Centisome position: 91.53

GC content: 38.62

Gene sequence:

>1344_bases
ATGTCAGAAAAACTTGATGAAGTAGATAGTAAGAGCCTGGACGAGATTAATGGTAGTATCAAGGTACCTAAGAATGCAGG
CTTTTGGAAGACGCTGATGGCGTACTCCGGACCCGGATTTTTAATTGCGGTTGGTTATATGGATCCAGGTAACTGGATTA
CGTCAATTGCGGGTGGGGCGCAATTTAGATATACGCTCCTTTCAGTTATTTTACTTTCTAGTTTAATCGCGATGCTTTTA
CAGGCAATGTCAGCGAGACTAGGAATTGTAACTGGAAAAGATTTAGCGCAGTTAACGCGGGAACGAACGAGTAAAAGAGT
TGGATTCTTGCTGTGGATTGTCGCTGAATTAGCGATTATGGCTACAGATATTGCCGAAATTATTGGATCTGGAATTGCAT
TGGAGCTGTTATTCCATATTCCATTGATTATTGGTATTTTGATTACAGCGGCAGATGTTTTGATATTGCTGCTATTAATG
AAGCTCGGTTTTAGAAAAATCGAAGCAATTGTTGCAACCTTAGTTGCTGTTATTTTAATTGTTTTTGCGTACGAAGTGCT
GCTTTCTGATCCAAGTATTTCAGGGATTATCAAAGGGTATGTACCTTCAGTTGAGATTTTAGGTAATAACTCAATGTTGT
ATCTATCACTAGGAATTGTCGGTGCGACAGTTATGCCCCATGATTTGTATCTGGGTTCTTCAATTTCACAAACTCGTGAA
GTGGACCGAAAAGATCGGGAAAATGTCGCTCAAGCAATTCGTTTTTCAACGATTGACTCTAATATGCAACTATTCTTAGC
TTTCATTGTTAATAGTTTACTATTGATTTTGGGAGCGGCCTTATTCTATGGAACGGATAGTTCACTAGGACGTTTCGTTG
ATTTGTTTAATGCTTTAAGTAATAACCAAATTGTTGGGGCCATTGCTAGCCCAGTACTTAGTATGCTATTTGCTGTAGCC
TTACTTGCTTCTGGACAAAGCTCAACAATTACCGGAACATTATCTGGTCAGATTATCATGGAAGGATTCATTCGACTACG
TGTCCCATTGTGGGTACAACGTTTGGTGACTCGAGTTCTTTCTGTGGCACCAGTTTTGATTTTTGCCATTTATTACCACG
GTGATGAAGCTAAAATTGAAAACTTACTAACGTTCTCGCAAGTATTCTTAAGTGTGGCTTTACCGTTTGCGGTAATTCCT
CTGGTTATATATACAAGCAGTAAAAAGTTGATGGGTGAATTTGCTAATCGAGCATGGGTAAAATGGTGTGCTTGGACTGC
AACAATTGTCTTGATTTTGTTAAATATATATTTAATCCTTCAAACGCTAGGTTTAATCAAATAA

Upstream 100 bases:

>100_bases
ATCCATTTTTTTGCTTTCTTATAAAAATGGATCAATTTTATGGTGGAGAGTTTATTTCAAGTTACCGAATTTCTAAACCA
ATAGAAAAGAGGGACTCAAT

Downstream 100 bases:

>100_bases
GACCTGATATATAAGCGTTTAATTAACTTAAATTGAACTTCAAAATTTGTTTCAAAGATACTCATTTCTAAACGAAATGG
GTATTTTTTTATCTTATGGT

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSEKLDEVDSKSLDEINGSIKVPKNAGFWKTLMAYSGPGFLIAVGYMDPGNWITSIAGGAQFRYTLLSVILLSSLIAMLL
QAMSARLGIVTGKDLAQLTRERTSKRVGFLLWIVAELAIMATDIAEIIGSGIALELLFHIPLIIGILITAADVLILLLLM
KLGFRKIEAIVATLVAVILIVFAYEVLLSDPSISGIIKGYVPSVEILGNNSMLYLSLGIVGATVMPHDLYLGSSISQTRE
VDRKDRENVAQAIRFSTIDSNMQLFLAFIVNSLLLILGAALFYGTDSSLGRFVDLFNALSNNQIVGAIASPVLSMLFAVA
LLASGQSSTITGTLSGQIIMEGFIRLRVPLWVQRLVTRVLSVAPVLIFAIYYHGDEAKIENLLTFSQVFLSVALPFAVIP
LVIYTSSKKLMGEFANRAWVKWCAWTATIVLILLNIYLILQTLGLIK

Sequences:

>Translated_447_residues
MSEKLDEVDSKSLDEINGSIKVPKNAGFWKTLMAYSGPGFLIAVGYMDPGNWITSIAGGAQFRYTLLSVILLSSLIAMLL
QAMSARLGIVTGKDLAQLTRERTSKRVGFLLWIVAELAIMATDIAEIIGSGIALELLFHIPLIIGILITAADVLILLLLM
KLGFRKIEAIVATLVAVILIVFAYEVLLSDPSISGIIKGYVPSVEILGNNSMLYLSLGIVGATVMPHDLYLGSSISQTRE
VDRKDRENVAQAIRFSTIDSNMQLFLAFIVNSLLLILGAALFYGTDSSLGRFVDLFNALSNNQIVGAIASPVLSMLFAVA
LLASGQSSTITGTLSGQIIMEGFIRLRVPLWVQRLVTRVLSVAPVLIFAIYYHGDEAKIENLLTFSQVFLSVALPFAVIP
LVIYTSSKKLMGEFANRAWVKWCAWTATIVLILLNIYLILQTLGLIK
>Mature_446_residues
SEKLDEVDSKSLDEINGSIKVPKNAGFWKTLMAYSGPGFLIAVGYMDPGNWITSIAGGAQFRYTLLSVILLSSLIAMLLQ
AMSARLGIVTGKDLAQLTRERTSKRVGFLLWIVAELAIMATDIAEIIGSGIALELLFHIPLIIGILITAADVLILLLLMK
LGFRKIEAIVATLVAVILIVFAYEVLLSDPSISGIIKGYVPSVEILGNNSMLYLSLGIVGATVMPHDLYLGSSISQTREV
DRKDRENVAQAIRFSTIDSNMQLFLAFIVNSLLLILGAALFYGTDSSLGRFVDLFNALSNNQIVGAIASPVLSMLFAVAL
LASGQSSTITGTLSGQIIMEGFIRLRVPLWVQRLVTRVLSVAPVLIFAIYYHGDEAKIENLLTFSQVFLSVALPFAVIPL
VIYTSSKKLMGEFANRAWVKWCAWTATIVLILLNIYLILQTLGLIK

Specific function: H(+)-stimulated, highly selective, manganese uptake system

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family

Homologues:

Organism=Homo sapiens, GI109255241, Length=465, Percent_Identity=33.9784946236559, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI295293167, Length=453, Percent_Identity=35.5408388520971, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI295293171, Length=453, Percent_Identity=35.5408388520971, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI295293169, Length=453, Percent_Identity=35.5408388520971, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI295293178, Length=453, Percent_Identity=35.5408388520971, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI295293175, Length=453, Percent_Identity=35.5408388520971, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI295293173, Length=453, Percent_Identity=35.5408388520971, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI10835169, Length=453, Percent_Identity=35.5408388520971, Blast_Score=238, Evalue=7e-63,
Organism=Escherichia coli, GI1788736, Length=419, Percent_Identity=36.2768496420048, Blast_Score=239, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI193210616, Length=461, Percent_Identity=33.1887201735358, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17569473, Length=407, Percent_Identity=34.6437346437346, Blast_Score=247, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI71999499, Length=469, Percent_Identity=32.409381663113, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71993856, Length=250, Percent_Identity=35.6, Blast_Score=165, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323062, Length=394, Percent_Identity=40.8629441624365, Blast_Score=252, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6324450, Length=422, Percent_Identity=35.0710900473934, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6321841, Length=422, Percent_Identity=37.914691943128, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24648607, Length=446, Percent_Identity=34.7533632286996, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI281362176, Length=446, Percent_Identity=34.7533632286996, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24648609, Length=446, Percent_Identity=34.7533632286996, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI45553443, Length=422, Percent_Identity=35.0710900473934, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNTH_PEDPA (Q03DK0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_805164.1
- STRING:   Q03DK0
- GeneID:   4417503
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1701
- NMPDR:   fig|278197.10.peg.1503
- eggNOG:   COG1914
- HOGENOM:   HBG312498
- OMA:   LACETAI
- PhylomeDB:   Q03DK0
- ProtClustDB:   PRK00701
- BioCyc:   PPEN278197:PEPE_1701-MONOMER
- HAMAP:   MF_00221
- InterPro:   IPR023056
- InterPro:   IPR001046
- PANTHER:   PTHR11706
- PRINTS:   PR00447
- TIGRFAMs:   TIGR01197

Pfam domain/function: PF01566 Nramp

EC number: NA

Molecular weight: Translated: 48621; Mature: 48489

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18a6e168)-; HASH(0x188a7194)-; HASH(0x17ec0b38)-; HASH(0x18ad8518)-; HASH(0x18c9edd0)-; HASH(0x18daff58)-; HASH(0x18dfa0e4)-; HASH(0x18bc6504)-; HASH(0x1821b430)-; HASH(0x18d5d570)-; HASH(0x181d14b4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKLDEVDSKSLDEINGSIKVPKNAGFWKTLMAYSGPGFLIAVGYMDPGNWITSIAGGA
CCCHHHHHCCCCHHHCCCCEECCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCC
QFRYTLLSVILLSSLIAMLLQAMSARLGIVTGKDLAQLTRERTSKRVGFLLWIVAELAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATDIAEIIGSGIALELLFHIPLIIGILITAADVLILLLLMKLGFRKIEAIVATLVAVILI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAYEVLLSDPSISGIIKGYVPSVEILGNNSMLYLSLGIVGATVMPHDLYLGSSISQTRE
HHHHHHHHCCCCHHHHHHCCCCCEEEECCCCEEEEEECHHHHHCCCCHHHCCCCHHHHHH
VDRKDRENVAQAIRFSTIDSNMQLFLAFIVNSLLLILGAALFYGTDSSLGRFVDLFNALS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
NNQIVGAIASPVLSMLFAVALLASGQSSTITGTLSGQIIMEGFIRLRVPLWVQRLVTRVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SVAPVLIFAIYYHGDEAKIENLLTFSQVFLSVALPFAVIPLVIYTSSKKLMGEFANRAWV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KWCAWTATIVLILLNIYLILQTLGLIK
HHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SEKLDEVDSKSLDEINGSIKVPKNAGFWKTLMAYSGPGFLIAVGYMDPGNWITSIAGGA
CCHHHHHCCCCHHHCCCCEECCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCC
QFRYTLLSVILLSSLIAMLLQAMSARLGIVTGKDLAQLTRERTSKRVGFLLWIVAELAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATDIAEIIGSGIALELLFHIPLIIGILITAADVLILLLLMKLGFRKIEAIVATLVAVILI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAYEVLLSDPSISGIIKGYVPSVEILGNNSMLYLSLGIVGATVMPHDLYLGSSISQTRE
HHHHHHHHCCCCHHHHHHCCCCCEEEECCCCEEEEEECHHHHHCCCCHHHCCCCHHHHHH
VDRKDRENVAQAIRFSTIDSNMQLFLAFIVNSLLLILGAALFYGTDSSLGRFVDLFNALS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
NNQIVGAIASPVLSMLFAVALLASGQSSTITGTLSGQIIMEGFIRLRVPLWVQRLVTRVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SVAPVLIFAIYYHGDEAKIENLLTFSQVFLSVALPFAVIPLVIYTSSKKLMGEFANRAWV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KWCAWTATIVLILLNIYLILQTLGLIK
HHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA