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The map label for this gene is rbsK [H]

Identifier: 116493427

GI number: 116493427

Start: 1673744

End: 1674652

Strand: Reverse

Name: rbsK [H]

Synonym: PEPE_1699

Alternate gene names: 116493427

Gene position: 1674652-1673744 (Counterclockwise)

Preceding gene: 116493428

Following gene: 116493426

Centisome position: 91.39

GC content: 37.4

Gene sequence:

>909_bases
ATGAACACTGTAACAATTATTGGGAGCATTAACTTAGACCGTACTATCCGAGTAAAACAAATGCCAAAACCAGGTGAAAC
CATGCATACGAAAGAAATTTTTTCAGCTGGTGGCGGAAAGGGAGCTAACCAAGCTGTAGCTGCTAAGCGTTCTGAAGCTA
AGACAAACTTTATTGGTGCAGTTGGTAATGACGATGCTGGCCGTGCAATGTTAGAATTATTGGAACATGAAAATATTGAT
ATGAGCGGAATTGAAACTTTAGATAACCAATCTACAGGACAAGCATACATAGTAGTAGATGACGCTGGTGAAAATCAAAT
CATGATTCATGCGGGTGCTAATACTGCATTTACTCCAGAATATGTCCAGTCTAAAGCTGATTTAATCAAAAATAGTGATT
TCATTATTGCTCAATTTGAAAGTTCTTTAGATTCAGTTACGGAAGCCTTTAAGATTGCTCGTGAAGCAGGCGTTAAAACA
ATCTTGAATCCCGCTCCAGCGGTTGAAAAGGTTCCTAGTGATTTATTAGCAGTAACGGATATGATCATTCCTAATGAAAC
TGAAACTGAAATTTTAACCGGAATCGAAGTAACAGATGAAGCAAGTATGAAGAAAGCTTCTAAAGCATTACATGATGAAG
GAATTGAAGCAGTTTTGATTACCATTGGTAGCAAAGGAACCTTCTACGATGTTAATGGTAAAAGTGGAATTATCCCCGCA
TTTAAGGTAAAGGCTGTTGATACAACTTCTGCTGGAGATACATTCATTGGAGCAATGAGCACCGTTTTGAATAAAGACTT
TAGTAACTTAGAAGATGCCATCTTATATGGTAATAAAGCTTCATCCCTAACTGTACAACGCTTTGGTGCACAACCATCAA
TCCCTTACAAAAAAGAATTGGAAAAATAG

Upstream 100 bases:

>100_bases
TTAATAGAATCAATGTGCTATATTTTTGATATGCTATTAAAACGTTTTCATAAAACGTTTTAAACAAGTAAAAAGATAAT
CGAAAACGGAGGAATCCATC

Downstream 100 bases:

>100_bases
GAGGAAATAACAATGAAGAAAACTAAAATGATTAATTCAGATATGTCACGGGTAATTGCTCAAATGGGTCACTTTGATAA
ATTAAGTATCGGTGATGCTG

Product: ribokinase family sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MNTVTIIGSINLDRTIRVKQMPKPGETMHTKEIFSAGGGKGANQAVAAKRSEAKTNFIGAVGNDDAGRAMLELLEHENID
MSGIETLDNQSTGQAYIVVDDAGENQIMIHAGANTAFTPEYVQSKADLIKNSDFIIAQFESSLDSVTEAFKIAREAGVKT
ILNPAPAVEKVPSDLLAVTDMIIPNETETEILTGIEVTDEASMKKASKALHDEGIEAVLITIGSKGTFYDVNGKSGIIPA
FKVKAVDTTSAGDTFIGAMSTVLNKDFSNLEDAILYGNKASSLTVQRFGAQPSIPYKKELEK

Sequences:

>Translated_302_residues
MNTVTIIGSINLDRTIRVKQMPKPGETMHTKEIFSAGGGKGANQAVAAKRSEAKTNFIGAVGNDDAGRAMLELLEHENID
MSGIETLDNQSTGQAYIVVDDAGENQIMIHAGANTAFTPEYVQSKADLIKNSDFIIAQFESSLDSVTEAFKIAREAGVKT
ILNPAPAVEKVPSDLLAVTDMIIPNETETEILTGIEVTDEASMKKASKALHDEGIEAVLITIGSKGTFYDVNGKSGIIPA
FKVKAVDTTSAGDTFIGAMSTVLNKDFSNLEDAILYGNKASSLTVQRFGAQPSIPYKKELEK
>Mature_302_residues
MNTVTIIGSINLDRTIRVKQMPKPGETMHTKEIFSAGGGKGANQAVAAKRSEAKTNFIGAVGNDDAGRAMLELLEHENID
MSGIETLDNQSTGQAYIVVDDAGENQIMIHAGANTAFTPEYVQSKADLIKNSDFIIAQFESSLDSVTEAFKIAREAGVKT
ILNPAPAVEKVPSDLLAVTDMIIPNETETEILTGIEVTDEASMKKASKALHDEGIEAVLITIGSKGTFYDVNGKSGIIPA
FKVKAVDTTSAGDTFIGAMSTVLNKDFSNLEDAILYGNKASSLTVQRFGAQPSIPYKKELEK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=37.3737373737374, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=44.8160535117057, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI87082343, Length=295, Percent_Identity=30.5084745762712, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788491, Length=264, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789432, Length=309, Percent_Identity=23.9482200647249, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788484, Length=260, Percent_Identity=22.3076923076923, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081971, Length=301, Percent_Identity=24.2524916943522, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=301, Percent_Identity=33.5548172757475, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=28.3987915407855, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=33.6633663366337, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=27.8688524590164, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32233; Mature: 32233

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVTIIGSINLDRTIRVKQMPKPGETMHTKEIFSAGGGKGANQAVAAKRSEAKTNFIGA
CCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEE
VGNDDAGRAMLELLEHENIDMSGIETLDNQSTGQAYIVVDDAGENQIMIHAGANTAFTPE
CCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHH
YVQSKADLIKNSDFIIAQFESSLDSVTEAFKIAREAGVKTILNPAPAVEKVPSDLLAVTD
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHCCHHHHHHHH
MIIPNETETEILTGIEVTDEASMKKASKALHDEGIEAVLITIGSKGTFYDVNGKSGIIPA
HHCCCCCCHHEEECCEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCE
FKVKAVDTTSAGDTFIGAMSTVLNKDFSNLEDAILYGNKASSLTVQRFGAQPSIPYKKEL
EEEEEEECCCCCCHHHHHHHHHHHCCHHCHHHHEEECCCCCCEEHEECCCCCCCCHHHHC
EK
CC
>Mature Secondary Structure
MNTVTIIGSINLDRTIRVKQMPKPGETMHTKEIFSAGGGKGANQAVAAKRSEAKTNFIGA
CCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEE
VGNDDAGRAMLELLEHENIDMSGIETLDNQSTGQAYIVVDDAGENQIMIHAGANTAFTPE
CCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHH
YVQSKADLIKNSDFIIAQFESSLDSVTEAFKIAREAGVKTILNPAPAVEKVPSDLLAVTD
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHHCCHHHHHHHH
MIIPNETETEILTGIEVTDEASMKKASKALHDEGIEAVLITIGSKGTFYDVNGKSGIIPA
HHCCCCCCHHEEECCEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCE
FKVKAVDTTSAGDTFIGAMSTVLNKDFSNLEDAILYGNKASSLTVQRFGAQPSIPYKKEL
EEEEEEECCCCCCHHHHHHHHHHHCCHHCHHHHEEECCCCCCEEHEECCCCCCCCHHHHC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]