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The map label for this gene is malR [H]

Identifier: 116492732

GI number: 116492732

Start: 974686

End: 975639

Strand: Reverse

Name: malR [H]

Synonym: PEPE_0969

Alternate gene names: 116492732

Gene position: 975639-974686 (Counterclockwise)

Preceding gene: 116492733

Following gene: 116492731

Centisome position: 53.24

GC content: 34.59

Gene sequence:

>954_bases
ATGATTACAATCAAAGATGTAGCTAAAGAGGCTGGAGTATCAGTTTCGACAGCTTCTCGAGCACTAAATAATAATCCTAG
AATTAGTGCAACAACCATTGAAAAAGTTAAGAAAATTGCTAAAGAATTAGACTATAAGCCCAATGCCAGCGCCAAAACTT
TGTCCTTAGGCAAAGCTAATGAAATTGGAGTGATTTACCCAGTAACCGCTGACGAAGATCCTGCTAATCCGTTTCATATT
GACTTAATGCGAGGAATTAACACAGCGTTACAACTCAAAAACTTTGTTTTATCTGTCGCAATTTGTCAAACTGAAGAAGC
GTTATTAAACAATGTGAAAAGAATGGTGGAACAAAGCCAAATTCACGATTTCTTGTTACTGTATTCTAAAGCAGACGATG
TAGTAACCAATTATCTTAGGAAGCAAGAGTTAAACTTTGTTATTATCGGTGAACCAACGAATGAAAATGACCGTTTTATT
GATAATGACAATATTTTAGCGGGACGTGAAGTTACTGAATTTATGTTTAACCAGTATAATGCTAAACATCCACTTTTTCT
CAGATCTACTTATAATTGGGAATATGAAAAAAAGCGTGAGTTAGGATATCAGCAAGTGATGAGCACTAAAAGCGGTTCAA
GCCCCTTAATATATAAGCTTGAAAAAAACGATAATAAAGTAGCTATCGATAAATATATGAAACACCATTTTGAGATTGAT
GCCATTATTGGAGCGGATGATATTGAATTACTAAGCTTTTATCATCTATTAAAAGATAACCAGCATATTAAAAACATCCC
CGCGATTTGTTTTAATAATAGTAGGTTGATTAGTCTAGCCGGCCCCACCGTTAATAAAGTTGATTTAAGACCACGGGAAC
TAGGTAAAAAAGCGGTTGAACTACTATTCGATTCCGAATTAAGAAAAGCGACAGTCGGGTTTGATATTATTTAA

Upstream 100 bases:

>100_bases
AGGAAAATTGTATTTTTAGGGCGCAGAGGGCGCTATGTAGAATTTCATCGTCTAGGAAGTTATACTTGTATATGTAAATA
TTAAATTTTGAGGTATATGC

Downstream 100 bases:

>100_bases
GAAAAGAGGGATTCCTCTTTTTTATTTGGTTAAAAAAAGCAAGCGTTTGCACAAAATAAGTGCAAACGCTTGCACAATTT
AAATCTCTATGTTAAATTAA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MITIKDVAKEAGVSVSTASRALNNNPRISATTIEKVKKIAKELDYKPNASAKTLSLGKANEIGVIYPVTADEDPANPFHI
DLMRGINTALQLKNFVLSVAICQTEEALLNNVKRMVEQSQIHDFLLLYSKADDVVTNYLRKQELNFVIIGEPTNENDRFI
DNDNILAGREVTEFMFNQYNAKHPLFLRSTYNWEYEKKRELGYQQVMSTKSGSSPLIYKLEKNDNKVAIDKYMKHHFEID
AIIGADDIELLSFYHLLKDNQHIKNIPAICFNNSRLISLAGPTVNKVDLRPRELGKKAVELLFDSELRKATVGFDII

Sequences:

>Translated_317_residues
MITIKDVAKEAGVSVSTASRALNNNPRISATTIEKVKKIAKELDYKPNASAKTLSLGKANEIGVIYPVTADEDPANPFHI
DLMRGINTALQLKNFVLSVAICQTEEALLNNVKRMVEQSQIHDFLLLYSKADDVVTNYLRKQELNFVIIGEPTNENDRFI
DNDNILAGREVTEFMFNQYNAKHPLFLRSTYNWEYEKKRELGYQQVMSTKSGSSPLIYKLEKNDNKVAIDKYMKHHFEID
AIIGADDIELLSFYHLLKDNQHIKNIPAICFNNSRLISLAGPTVNKVDLRPRELGKKAVELLFDSELRKATVGFDII
>Mature_317_residues
MITIKDVAKEAGVSVSTASRALNNNPRISATTIEKVKKIAKELDYKPNASAKTLSLGKANEIGVIYPVTADEDPANPFHI
DLMRGINTALQLKNFVLSVAICQTEEALLNNVKRMVEQSQIHDFLLLYSKADDVVTNYLRKQELNFVIIGEPTNENDRFI
DNDNILAGREVTEFMFNQYNAKHPLFLRSTYNWEYEKKRELGYQQVMSTKSGSSPLIYKLEKNDNKVAIDKYMKHHFEID
AIIGADDIELLSFYHLLKDNQHIKNIPAICFNNSRLISLAGPTVNKVDLRPRELGKKAVELLFDSELRKATVGFDII

Specific function: Transcriptional repressor of the malA gene for maltase [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=24.2811501597444, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=23.8993710691824, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788474, Length=214, Percent_Identity=30.3738317757009, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35950; Mature: 35950

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKDVAKEAGVSVSTASRALNNNPRISATTIEKVKKIAKELDYKPNASAKTLSLGKAN
CEEHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
EIGVIYPVTADEDPANPFHIDLMRGINTALQLKNFVLSVAICQTEEALLNNVKRMVEQSQ
CCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHDFLLLYSKADDVVTNYLRKQELNFVIIGEPTNENDRFIDNDNILAGREVTEFMFNQYN
HHHEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCEECCCCEEECHHHHHHHHHHCC
AKHPLFLRSTYNWEYEKKRELGYQQVMSTKSGSSPLIYKLEKNDNKVAIDKYMKHHFEID
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEHHHHHHHHHCEEE
AIIGADDIELLSFYHLLKDNQHIKNIPAICFNNSRLISLAGPTVNKVDLRPRELGKKAVE
EEECCCHHHHHHHHHHHCCCCHHHCCCEEEECCCEEEEEECCCCCEECCCHHHHHHHHHH
LLFDSELRKATVGFDII
HHHHHHHHHHHCCEECC
>Mature Secondary Structure
MITIKDVAKEAGVSVSTASRALNNNPRISATTIEKVKKIAKELDYKPNASAKTLSLGKAN
CEEHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
EIGVIYPVTADEDPANPFHIDLMRGINTALQLKNFVLSVAICQTEEALLNNVKRMVEQSQ
CCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHDFLLLYSKADDVVTNYLRKQELNFVIIGEPTNENDRFIDNDNILAGREVTEFMFNQYN
HHHEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCEECCCCEEECHHHHHHHHHHCC
AKHPLFLRSTYNWEYEKKRELGYQQVMSTKSGSSPLIYKLEKNDNKVAIDKYMKHHFEID
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEHHHHHHHHHCEEE
AIIGADDIELLSFYHLLKDNQHIKNIPAICFNNSRLISLAGPTVNKVDLRPRELGKKAVE
EEECCCHHHHHHHHHHHCCCCHHHCCCEEEECCCEEEEEECCCCCEECCCHHHHHHHHHH
LLFDSELRKATVGFDII
HHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7730272 [H]