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The map label for this gene is comFA [H]

Identifier: 116492228

GI number: 116492228

Start: 475595

End: 476914

Strand: Direct

Name: comFA [H]

Synonym: PEPE_0425

Alternate gene names: 116492228

Gene position: 475595-476914 (Clockwise)

Preceding gene: 116492226

Following gene: 116492229

Centisome position: 25.95

GC content: 42.12

Gene sequence:

>1320_bases
ATGGAAGAAATAGAAAAGCAAAAATACTATGGACGGCTAGTTTTACAGCCAATTAATGCAGTACCAACGGATTCGCTTGA
TTGTCGACCAGCAATTGTAATGAAAGGAAATCAAATTCACTGCCAACGATGTGGCGCAATTACCTCTAGTAGGGATGGGG
CATTACCAGATCATCAATTCTATTGCCGTAAATGTATCAACTTAGGTAGAGTTTCTACCCTGGTTCAGTTAGCGACCATT
CCTGAGCCTAATAATTTTGTGGCGAATCAGAGTTATTTAGAATGGCCGGGGAAGTTAACTGCTCCGCAAGCTCGCTGTTC
AAAAGCGATTATTAATTCCATTGATCAGCAACAAAATCGTTTACTCTGGGCGGTTACTGGGGCAGGGAAAACTGAAATGC
TCTTCCCGGGAATTAATCATGCTTTACAAAAGCAAAAAAGGATATGTGTGGCTTCGCCCCGAATTGACGTAGTCTTAGAG
CTGTTTCCTCGATTTCAAGAAGCTTTTCCACAGGCTAAAATTGCCTTGCTTCACGGTCGATCCCCAGCTCCCTATGAATA
TACGCAGTTTGTGCTCTGTACAACGCATCAATTACTACGATTTTACCACGCCTTTGATGTTTTAATCATTGATGAAGTGG
ATTCTTTTCCCTATGCGATGAATCCTGAGCTGCATTATGCAACCAAGCAGGCCCGTAAATTACAAGGATCGACCATTTAT
CTTACAGCTACCCCGGACGGAAAACTTTTACAGCAAAGTCGGCAAGCTAAATTAGCTACCAGTTATCTAACTCGGCGTTT
TCATGGACATCCACTACCAGAAATTAAAGTAGTGAGTGGGCAAAATTGGATAAAAAAGTTAAGAAAGGGTCGATTGCCAA
GCCCATTAAGCCGATTTATTAAGGAACAAATTCAAGCACAGCGCCAATTTTTAATCTTTGTTCCCAAAATTGAGGTGCTA
CCGAAAGTATTGGAGGCTTTGCAACAGGTCTTTCCCACGGTCAAAGTTTTAACAGTTCACGCAGCAGATCCAGAGCGGGT
GGCTAAAGTGCAAATGATGCGTAAACAGGAAATTGACGCTTTAATTACGACCACTATTCTTGAACGTGGAGTGACTTTTC
CAGGTATTGATGTCGCTGTTTTAGGAGCAGATGATGCCGTCTTTTCCATGGCAGCATTGGTTCAAATTGCTGGTCGAGTT
GGTCGAAGTCCCCAACGACCCAAGGGGACTGTATTATTTATTTGTCCAATGTTAAATCGAAATATAAAAAGAGCTCAAGC
CCAAACCAAATTTATGAATCGAAAGGCGAGTGAATGTTGA

Upstream 100 bases:

>100_bases
ATAAATCTTGATTTTTTGATATCTTGTTCAATTTTAAAATTTTCTTTGACGGATAAGATTGGTTTCAAGAAAAAGACTCC
TTTTTGGGTATTTAATAAAT

Downstream 100 bases:

>100_bases
AAAGTTGCTTACTTTGTAACCGAGGATTAAATAATAATTTAGATTTATCTTTTATTTTAAGTTTCAGAAAAATTACTCCG
AAGTTAGTTTGCGAGGGGTG

Product: superfamily II DNA/RNA helicase

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MEEIEKQKYYGRLVLQPINAVPTDSLDCRPAIVMKGNQIHCQRCGAITSSRDGALPDHQFYCRKCINLGRVSTLVQLATI
PEPNNFVANQSYLEWPGKLTAPQARCSKAIINSIDQQQNRLLWAVTGAGKTEMLFPGINHALQKQKRICVASPRIDVVLE
LFPRFQEAFPQAKIALLHGRSPAPYEYTQFVLCTTHQLLRFYHAFDVLIIDEVDSFPYAMNPELHYATKQARKLQGSTIY
LTATPDGKLLQQSRQAKLATSYLTRRFHGHPLPEIKVVSGQNWIKKLRKGRLPSPLSRFIKEQIQAQRQFLIFVPKIEVL
PKVLEALQQVFPTVKVLTVHAADPERVAKVQMMRKQEIDALITTTILERGVTFPGIDVAVLGADDAVFSMAALVQIAGRV
GRSPQRPKGTVLFICPMLNRNIKRAQAQTKFMNRKASEC

Sequences:

>Translated_439_residues
MEEIEKQKYYGRLVLQPINAVPTDSLDCRPAIVMKGNQIHCQRCGAITSSRDGALPDHQFYCRKCINLGRVSTLVQLATI
PEPNNFVANQSYLEWPGKLTAPQARCSKAIINSIDQQQNRLLWAVTGAGKTEMLFPGINHALQKQKRICVASPRIDVVLE
LFPRFQEAFPQAKIALLHGRSPAPYEYTQFVLCTTHQLLRFYHAFDVLIIDEVDSFPYAMNPELHYATKQARKLQGSTIY
LTATPDGKLLQQSRQAKLATSYLTRRFHGHPLPEIKVVSGQNWIKKLRKGRLPSPLSRFIKEQIQAQRQFLIFVPKIEVL
PKVLEALQQVFPTVKVLTVHAADPERVAKVQMMRKQEIDALITTTILERGVTFPGIDVAVLGADDAVFSMAALVQIAGRV
GRSPQRPKGTVLFICPMLNRNIKRAQAQTKFMNRKASEC
>Mature_439_residues
MEEIEKQKYYGRLVLQPINAVPTDSLDCRPAIVMKGNQIHCQRCGAITSSRDGALPDHQFYCRKCINLGRVSTLVQLATI
PEPNNFVANQSYLEWPGKLTAPQARCSKAIINSIDQQQNRLLWAVTGAGKTEMLFPGINHALQKQKRICVASPRIDVVLE
LFPRFQEAFPQAKIALLHGRSPAPYEYTQFVLCTTHQLLRFYHAFDVLIIDEVDSFPYAMNPELHYATKQARKLQGSTIY
LTATPDGKLLQQSRQAKLATSYLTRRFHGHPLPEIKVVSGQNWIKKLRKGRLPSPLSRFIKEQIQAQRQFLIFVPKIEVL
PKVLEALQQVFPTVKVLTVHAADPERVAKVQMMRKQEIDALITTTILERGVTFPGIDVAVLGADDAVFSMAALVQIAGRV
GRSPQRPKGTVLFICPMLNRNIKRAQAQTKFMNRKASEC

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49490; Mature: 49490

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIEKQKYYGRLVLQPINAVPTDSLDCRPAIVMKGNQIHCQRCGAITSSRDGALPDHQF
CCHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEEECCEEEHHHHCCCCCCCCCCCCCHHH
YCRKCINLGRVSTLVQLATIPEPNNFVANQSYLEWPGKLTAPQARCSKAIINSIDQQQNR
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
LLWAVTGAGKTEMLFPGINHALQKQKRICVASPRIDVVLELFPRFQEAFPQAKIALLHGR
EEEEEECCCCCEEECCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECC
SPAPYEYTQFVLCTTHQLLRFYHAFDVLIIDEVDSFPYAMNPELHYATKQARKLQGSTIY
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEE
LTATPDGKLLQQSRQAKLATSYLTRRFHGHPLPEIKVVSGQNWIKKLRKGRLPSPLSRFI
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCCCHHHHHH
KEQIQAQRQFLIFVPKIEVLPKVLEALQQVFPTVKVLTVHAADPERVAKVQMMRKQEIDA
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
LITTTILERGVTFPGIDVAVLGADDAVFSMAALVQIAGRVGRSPQRPKGTVLFICPMLNR
HHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
NIKRAQAQTKFMNRKASEC
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEIEKQKYYGRLVLQPINAVPTDSLDCRPAIVMKGNQIHCQRCGAITSSRDGALPDHQF
CCHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEEECCEEEHHHHCCCCCCCCCCCCCHHH
YCRKCINLGRVSTLVQLATIPEPNNFVANQSYLEWPGKLTAPQARCSKAIINSIDQQQNR
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
LLWAVTGAGKTEMLFPGINHALQKQKRICVASPRIDVVLELFPRFQEAFPQAKIALLHGR
EEEEEECCCCCEEECCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECC
SPAPYEYTQFVLCTTHQLLRFYHAFDVLIIDEVDSFPYAMNPELHYATKQARKLQGSTIY
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEE
LTATPDGKLLQQSRQAKLATSYLTRRFHGHPLPEIKVVSGQNWIKKLRKGRLPSPLSRFI
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCCCHHHHHH
KEQIQAQRQFLIFVPKIEVLPKVLEALQQVFPTVKVLTVHAADPERVAKVQMMRKQEIDA
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
LITTTILERGVTFPGIDVAVLGADDAVFSMAALVQIAGRVGRSPQRPKGTVLFICPMLNR
HHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
NIKRAQAQTKFMNRKASEC
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]