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The map label for this gene is tagO [H]

Identifier: 116492226

GI number: 116492226

Start: 473734

End: 474894

Strand: Direct

Name: tagO [H]

Synonym: PEPE_0423

Alternate gene names: 116492226

Gene position: 473734-474894 (Clockwise)

Preceding gene: 116492225

Following gene: 116492228

Centisome position: 25.85

GC content: 36.52

Gene sequence:

>1161_bases
ATGCGATTTGAAATAATTGTTAGTTTATTTGCGACAATGATCATTTCGGCGATCTTAACACCATTTGTCCGGAGGATTTC
ATTCAAAGTTGGTGCCATTGACAAACCGACAGCCAGGCGAGTCAATAAAGTACCAATGCCAACCATGGGGGGATTGGCAA
TCTTCATTGCCTTCAATTTCTCATTATTTTTCTTATTGAGAAATCAAATACCTAATCCGCAGTTTTACGGAATTTTCTTC
GGGGAATGCATTATTTTAGTAACAGGAATTATCGATGATATTTTTGAATTAAGACCTATACAAAAAATGATTGGAATCTT
GTTAGCGGCGTTAGCGGTGTATCTATTTGCTAACGTTCGGATGACGACGTTAACTTTCCCATTTATTGGAATTGTTAACT
TCGGGTGGTTTTCGTTACCAATTACGTTGCTATGGATAGCAGCTATTACAAATGCGATTAATTTATTAGATGGGTTAGAT
GGTCTAGCGACTGGGGTAACAATCATTGCGTTGTTTACCACAGGATTTACCGGACTATTCTTTCTACCATCTACTAATAT
CTACATTGTAATCATGATTTTTACCTTGGTAGCAGCTGAAATTGGTTTTTTACCTTACAATTTCTTTCCAGCACGGATTT
ATCTCGGTGATACGGGAGCTTTATTTATTGGATTTATGATTTCAATTTTCTCACTATCTGGTTTGAAAAATGCAACCTTT
ATCACAATTTTAATTCCAGTTATGATTTTGGGTGTGCCACTGACTGATACGGTTTATGCAATTTTGAGAAGATTATTAAA
TAAGGAATCTATTTCACACGCTGATAAACGCCATCTACATCATCGTTTGATGCAAATGGGCTTAACCCATCGACAAACAG
TGTTAGTGATTTATGGAATTTCACTAATCTTTTCCTTTATTGCGCTGCTATATCCCGTTTCTACGTTGTGGGGCTCAGTG
TTATTAACCATCGGAATTTTGATTGGAATCGAGATTTTTGTGGAAGCAATTGGATTAGTGGGCGAAAACCGTACGCCAAT
GCTAAATTGGATTCGAAAGCTCGTACGCTCTAATACTTCTAAAGTAGATAGTAATGAATTTAAAGAAGAGAACACTTTAA
AAGATAAGGTTCGCACACGTAGTGAACGCCATAAAAAATGA

Upstream 100 bases:

>100_bases
AAAAATAATTTAAATTCTTTGCATTTTTAGTGAAGAAGATTGTATAAGGCTCATGAGTTTAGGTATAATGTGCTTATTAC
GAACAAAAAGAGGACAAATT

Downstream 100 bases:

>100_bases
GGATAATAACGATATTAGTCGTTGTCATCCTCATTTTTTTGATATGGAATTTGAACTCGTTTGGTACCTAAATCCTTAAA
GGCCACGTTCCCACTAAAAA

Product: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRFEIIVSLFATMIISAILTPFVRRISFKVGAIDKPTARRVNKVPMPTMGGLAIFIAFNFSLFFLLRNQIPNPQFYGIFF
GECIILVTGIIDDIFELRPIQKMIGILLAALAVYLFANVRMTTLTFPFIGIVNFGWFSLPITLLWIAAITNAINLLDGLD
GLATGVTIIALFTTGFTGLFFLPSTNIYIVIMIFTLVAAEIGFLPYNFFPARIYLGDTGALFIGFMISIFSLSGLKNATF
ITILIPVMILGVPLTDTVYAILRRLLNKESISHADKRHLHHRLMQMGLTHRQTVLVIYGISLIFSFIALLYPVSTLWGSV
LLTIGILIGIEIFVEAIGLVGENRTPMLNWIRKLVRSNTSKVDSNEFKEENTLKDKVRTRSERHKK

Sequences:

>Translated_386_residues
MRFEIIVSLFATMIISAILTPFVRRISFKVGAIDKPTARRVNKVPMPTMGGLAIFIAFNFSLFFLLRNQIPNPQFYGIFF
GECIILVTGIIDDIFELRPIQKMIGILLAALAVYLFANVRMTTLTFPFIGIVNFGWFSLPITLLWIAAITNAINLLDGLD
GLATGVTIIALFTTGFTGLFFLPSTNIYIVIMIFTLVAAEIGFLPYNFFPARIYLGDTGALFIGFMISIFSLSGLKNATF
ITILIPVMILGVPLTDTVYAILRRLLNKESISHADKRHLHHRLMQMGLTHRQTVLVIYGISLIFSFIALLYPVSTLWGSV
LLTIGILIGIEIFVEAIGLVGENRTPMLNWIRKLVRSNTSKVDSNEFKEENTLKDKVRTRSERHKK
>Mature_386_residues
MRFEIIVSLFATMIISAILTPFVRRISFKVGAIDKPTARRVNKVPMPTMGGLAIFIAFNFSLFFLLRNQIPNPQFYGIFF
GECIILVTGIIDDIFELRPIQKMIGILLAALAVYLFANVRMTTLTFPFIGIVNFGWFSLPITLLWIAAITNAINLLDGLD
GLATGVTIIALFTTGFTGLFFLPSTNIYIVIMIFTLVAAEIGFLPYNFFPARIYLGDTGALFIGFMISIFSLSGLKNATF
ITILIPVMILGVPLTDTVYAILRRLLNKESISHADKRHLHHRLMQMGLTHRQTVLVIYGISLIFSFIALLYPVSTLWGSV
LLTIGILIGIEIFVEAIGLVGENRTPMLNWIRKLVRSNTSKVDSNEFKEENTLKDKVRTRSERHKK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=288, Percent_Identity=27.7777777777778, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786275, Length=345, Percent_Identity=26.9565217391304, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 43295; Mature: 43295

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFEIIVSLFATMIISAILTPFVRRISFKVGAIDKPTARRVNKVPMPTMGGLAIFIAFNF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHH
SLFFLLRNQIPNPQFYGIFFGECIILVTGIIDDIFELRPIQKMIGILLAALAVYLFANVR
HHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MTTLTFPFIGIVNFGWFSLPITLLWIAAITNAINLLDGLDGLATGVTIIALFTTGFTGLF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEE
FLPSTNIYIVIMIFTLVAAEIGFLPYNFFPARIYLGDTGALFIGFMISIFSLSGLKNATF
EECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHH
ITILIPVMILGVPLTDTVYAILRRLLNKESISHADKRHLHHRLMQMGLTHRQTVLVIYGI
HHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLIFSFIALLYPVSTLWGSVLLTIGILIGIEIFVEAIGLVGENRTPMLNWIRKLVRSNTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
KVDSNEFKEENTLKDKVRTRSERHKK
CCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFEIIVSLFATMIISAILTPFVRRISFKVGAIDKPTARRVNKVPMPTMGGLAIFIAFNF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHH
SLFFLLRNQIPNPQFYGIFFGECIILVTGIIDDIFELRPIQKMIGILLAALAVYLFANVR
HHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MTTLTFPFIGIVNFGWFSLPITLLWIAAITNAINLLDGLDGLATGVTIIALFTTGFTGLF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEE
FLPSTNIYIVIMIFTLVAAEIGFLPYNFFPARIYLGDTGALFIGFMISIFSLSGLKNATF
EECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHH
ITILIPVMILGVPLTDTVYAILRRLLNKESISHADKRHLHHRLMQMGLTHRQTVLVIYGI
HHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLIFSFIALLYPVSTLWGSVLLTIGILIGIEIFVEAIGLVGENRTPMLNWIRKLVRSNTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
KVDSNEFKEENTLKDKVRTRSERHKK
CCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]