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The map label for this gene is yfmM [H]

Identifier: 116492180

GI number: 116492180

Start: 422351

End: 423901

Strand: Direct

Name: yfmM [H]

Synonym: PEPE_0377

Alternate gene names: 116492180

Gene position: 422351-423901 (Clockwise)

Preceding gene: 116492178

Following gene: 116492184

Centisome position: 23.05

GC content: 37.91

Gene sequence:

>1551_bases
ATGAGTTTATTATCAGTTGAGCATTTGAGCCATGGTTTTGCGGACAAAGAGCTCTACGAAGATGCAAATTTTGAGTTAAA
TAAAGAAGACCACATGGGAATTGTGGGACAAAATGGTGCTGGTAAAAGTACGTTAATCAAGATTTTAACGGGGGAAACCT
TGCCAGACAAAGGTCGTATTATTTGGCAAAATAAAGTGACGTATGGTTACTTAGACCAGTATGCGGACATTCCTAAGGAA
GATACGTTGTATGAATTTTTAACGACCGCATATGCAGAGTTATTTCGTCAACGTGATTTGATGGAGAAGTACTATGCAGA
TTACGCTGAAAATTTAGACGATAAGTTGCTAGAAAAAGCTGGAAGAATTCAGGAAAATTTAGATGCCAATAATTTCTATG
ATATTGATACGGAAATTAATCGAGTAATGACCGGTTTGGGTCTCGACGATATCGGCAAAGATCATATCGTAAGCGAAATG
AGTGGTGGACAACGTTCCAAGATTATTTTGGCTAAGTTACTTCTTCAAAATCCAGACGTTTTGATCTTGGATGAACCGAC
AAACTATTTAGATACTGCTCATATTAGTTGGTTGGCAGATTACTTGAATGGCTTTGAAGGAGCCTTCATGGTAATTTCCC
ATGACTACGATTTCTTGCAGAAGGTTACTAACTGTATTTGTGATGTTTCATTTAATAAAATTACTAAGTATCGTGGTGAC
TTCCAATCAGCAATGCGTCAAAAAGATGCGCGTAAGGAAGCCCAATTAAAAGCGTTTGAAAAACAACAAGTAGTGATTGA
AAAAGCTGAAAACTTCATTCGTAAGAATAAAGCCGGTCAACGTTCGACGATGGCTAAATCACGGGAGAAGATGTTAAATC
GGATGGAAAAAATCGATCCACCTAGTGAAAACTTAAAGGGTCATTTTGATTTTCCATATCTCGATACTGGATCCCAAAAT
GCAGTTGCTGTGAATAAATTAGCGGTAGGTTACGGCAAGAAGCAATTGCTTGAACCAGTGACATTTTCAATGTCGGCGGG
CGAAAAAGTAGCTTTCTCTGGGTTTAACGGTGCGGGTAAGTCAACCTTGATTAAGAGTATCTTAGGAGTAATTCCAGCTT
TAGGTGGAGAAGCCCATTTTTCACCATCTGCCAAAGTTAATTACTTCACCCAAGAATTAATATGGGATAATCCTAAATTG
ACACCATTAGAAACCATTCAAAACCAATACCCTAAGATGTTGCCTAAAACCATTCGGACTAAATTAGCTAAGTGTGGAAT
CAATGCTGCTGATACTATGAAGCCGATGAAACAGCTTAGTGGTGGAGAACAAACTAAGGTTAAATTAGCTTTAATGGAGT
TGATTGATTCAAATTTCTTAATCATGGATGAACCAACAAACCATTTGGATGATGAAACGAAGCGGGCCTTAAGTGAAGCG
TTACAACGCTTTAAAGGCAATTTGATCGTTGTATCCCATGAGGATAGTTTCTATTCCCAATGGATTGATAAAGAAATCAA
CGTGGAAAAATTACGTCTAGATCGCGAATAA

Upstream 100 bases:

>100_bases
ATAACGAGATTAAGTATAGCATAGGCAAATTGGATTGACGATTTGTATAAATTCATGCTACGGTGGTTATTAGTTATTTT
AGAAAAGTTAAGGTGAAAAA

Downstream 100 bases:

>100_bases
CCAAGCAAAAAAGCAACCCCGTGGGGTTGCTTTTTTAATACTCAATAGCTTAAAAGTCTGTGGCATCTGGATCCTGAGCT
AGACCAGCTACACCATGGAA

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSLLSVEHLSHGFADKELYEDANFELNKEDHMGIVGQNGAGKSTLIKILTGETLPDKGRIIWQNKVTYGYLDQYADIPKE
DTLYEFLTTAYAELFRQRDLMEKYYADYAENLDDKLLEKAGRIQENLDANNFYDIDTEINRVMTGLGLDDIGKDHIVSEM
SGGQRSKIILAKLLLQNPDVLILDEPTNYLDTAHISWLADYLNGFEGAFMVISHDYDFLQKVTNCICDVSFNKITKYRGD
FQSAMRQKDARKEAQLKAFEKQQVVIEKAENFIRKNKAGQRSTMAKSREKMLNRMEKIDPPSENLKGHFDFPYLDTGSQN
AVAVNKLAVGYGKKQLLEPVTFSMSAGEKVAFSGFNGAGKSTLIKSILGVIPALGGEAHFSPSAKVNYFTQELIWDNPKL
TPLETIQNQYPKMLPKTIRTKLAKCGINAADTMKPMKQLSGGEQTKVKLALMELIDSNFLIMDEPTNHLDDETKRALSEA
LQRFKGNLIVVSHEDSFYSQWIDKEINVEKLRLDRE

Sequences:

>Translated_516_residues
MSLLSVEHLSHGFADKELYEDANFELNKEDHMGIVGQNGAGKSTLIKILTGETLPDKGRIIWQNKVTYGYLDQYADIPKE
DTLYEFLTTAYAELFRQRDLMEKYYADYAENLDDKLLEKAGRIQENLDANNFYDIDTEINRVMTGLGLDDIGKDHIVSEM
SGGQRSKIILAKLLLQNPDVLILDEPTNYLDTAHISWLADYLNGFEGAFMVISHDYDFLQKVTNCICDVSFNKITKYRGD
FQSAMRQKDARKEAQLKAFEKQQVVIEKAENFIRKNKAGQRSTMAKSREKMLNRMEKIDPPSENLKGHFDFPYLDTGSQN
AVAVNKLAVGYGKKQLLEPVTFSMSAGEKVAFSGFNGAGKSTLIKSILGVIPALGGEAHFSPSAKVNYFTQELIWDNPKL
TPLETIQNQYPKMLPKTIRTKLAKCGINAADTMKPMKQLSGGEQTKVKLALMELIDSNFLIMDEPTNHLDDETKRALSEA
LQRFKGNLIVVSHEDSFYSQWIDKEINVEKLRLDRE
>Mature_515_residues
SLLSVEHLSHGFADKELYEDANFELNKEDHMGIVGQNGAGKSTLIKILTGETLPDKGRIIWQNKVTYGYLDQYADIPKED
TLYEFLTTAYAELFRQRDLMEKYYADYAENLDDKLLEKAGRIQENLDANNFYDIDTEINRVMTGLGLDDIGKDHIVSEMS
GGQRSKIILAKLLLQNPDVLILDEPTNYLDTAHISWLADYLNGFEGAFMVISHDYDFLQKVTNCICDVSFNKITKYRGDF
QSAMRQKDARKEAQLKAFEKQQVVIEKAENFIRKNKAGQRSTMAKSREKMLNRMEKIDPPSENLKGHFDFPYLDTGSQNA
VAVNKLAVGYGKKQLLEPVTFSMSAGEKVAFSGFNGAGKSTLIKSILGVIPALGGEAHFSPSAKVNYFTQELIWDNPKLT
PLETIQNQYPKMLPKTIRTKLAKCGINAADTMKPMKQLSGGEQTKVKLALMELIDSNFLIMDEPTNHLDDETKRALSEAL
QRFKGNLIVVSHEDSFYSQWIDKEINVEKLRLDRE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=501, Percent_Identity=29.7405189620758, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI27881506, Length=517, Percent_Identity=28.8201160541586, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI10947137, Length=515, Percent_Identity=28.1553398058252, Blast_Score=179, Evalue=8e-45,
Organism=Homo sapiens, GI10947135, Length=537, Percent_Identity=27.0018621973929, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI69354671, Length=537, Percent_Identity=27.1880819366853, Blast_Score=162, Evalue=9e-40,
Organism=Escherichia coli, GI1789751, Length=479, Percent_Identity=31.3152400835073, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1787182, Length=511, Percent_Identity=31.1154598825832, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI2367384, Length=482, Percent_Identity=32.3651452282158, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787041, Length=501, Percent_Identity=28.3433133732535, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI48994997, Length=222, Percent_Identity=26.5765765765766, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788165, Length=185, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788506, Length=206, Percent_Identity=29.126213592233, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786398, Length=202, Percent_Identity=23.2673267326733, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=523, Percent_Identity=27.151051625239, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17555318, Length=509, Percent_Identity=27.1119842829077, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17559834, Length=517, Percent_Identity=26.8858800773694, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320874, Length=507, Percent_Identity=30.7692307692308, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6321121, Length=533, Percent_Identity=27.7673545966229, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6325030, Length=397, Percent_Identity=26.7002518891688, Blast_Score=106, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6323278, Length=417, Percent_Identity=26.1390887290168, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324314, Length=407, Percent_Identity=25.0614250614251, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24666836, Length=502, Percent_Identity=28.0876494023904, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24642252, Length=529, Percent_Identity=27.7882797731569, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI18859989, Length=529, Percent_Identity=27.7882797731569, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24641342, Length=525, Percent_Identity=28.1904761904762, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24661270, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355589, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 58454; Mature: 58323

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLSVEHLSHGFADKELYEDANFELNKEDHMGIVGQNGAGKSTLIKILTGETLPDKGRI
CCCCCHHHHHCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCHHHEEEEEECCCCCCCCCE
IWQNKVTYGYLDQYADIPKEDTLYEFLTTAYAELFRQRDLMEKYYADYAENLDDKLLEKA
EEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
GRIQENLDANNFYDIDTEINRVMTGLGLDDIGKDHIVSEMSGGQRSKIILAKLLLQNPDV
HHHHHCCCCCCEEECHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCE
LILDEPTNYLDTAHISWLADYLNGFEGAFMVISHDYDFLQKVTNCICDVSFNKITKYRGD
EEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
FQSAMRQKDARKEAQLKAFEKQQVVIEKAENFIRKNKAGQRSTMAKSREKMLNRMEKIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
PSENLKGHFDFPYLDTGSQNAVAVNKLAVGYGKKQLLEPVTFSMSAGEKVAFSGFNGAGK
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCHHHHHCCHHEECCCCCEEEECCCCCCCH
STLIKSILGVIPALGGEAHFSPSAKVNYFTQELIWDNPKLTPLETIQNQYPKMLPKTIRT
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KLAKCGINAADTMKPMKQLSGGEQTKVKLALMELIDSNFLIMDEPTNHLDDETKRALSEA
HHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHH
LQRFKGNLIVVSHEDSFYSQWIDKEINVEKLRLDRE
HHHHCCCEEEEECCCHHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
SLLSVEHLSHGFADKELYEDANFELNKEDHMGIVGQNGAGKSTLIKILTGETLPDKGRI
CCCCHHHHHCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCHHHEEEEEECCCCCCCCCE
IWQNKVTYGYLDQYADIPKEDTLYEFLTTAYAELFRQRDLMEKYYADYAENLDDKLLEKA
EEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
GRIQENLDANNFYDIDTEINRVMTGLGLDDIGKDHIVSEMSGGQRSKIILAKLLLQNPDV
HHHHHCCCCCCEEECHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCE
LILDEPTNYLDTAHISWLADYLNGFEGAFMVISHDYDFLQKVTNCICDVSFNKITKYRGD
EEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
FQSAMRQKDARKEAQLKAFEKQQVVIEKAENFIRKNKAGQRSTMAKSREKMLNRMEKIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
PSENLKGHFDFPYLDTGSQNAVAVNKLAVGYGKKQLLEPVTFSMSAGEKVAFSGFNGAGK
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCHHHHHCCHHEECCCCCEEEECCCCCCCH
STLIKSILGVIPALGGEAHFSPSAKVNYFTQELIWDNPKLTPLETIQNQYPKMLPKTIRT
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KLAKCGINAADTMKPMKQLSGGEQTKVKLALMELIDSNFLIMDEPTNHLDDETKRALSEA
HHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHH
LQRFKGNLIVVSHEDSFYSQWIDKEINVEKLRLDRE
HHHHCCCEEEEECCCHHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]