Click here to switch to the map view.

The map label for this gene is mdh [H]

Identifier: 116327882

GI number: 116327882

Start: 1378466

End: 1379551

Strand: Direct

Name: mdh [H]

Synonym: LBL_1166

Alternate gene names: 116327882

Gene position: 1378466-1379551 (Clockwise)

Preceding gene: 116327881

Following gene: 116327883

Centisome position: 38.14

GC content: 35.45

Gene sequence:

>1086_bases
ATGTCAATAGATCTTCCTAATTCAAAAAATGTCCTTCAATATGTTTTCGGGGACGGTGCTTTGAAATCCCTAAATAAAAT
TTTAAAACCAAAAAGAGAAAAAAATACAAATGCAGTTTTCTTTATCGATATCTATTTTAAAGATAAAAATATAATTTCTT
CGTTACCATTAGAGAAAGAAGATTTAGTTTTTTATTATGACTCTGCTCATGAGCCGAAGACGGATTACATTGATGAGTTG
AGAGATCAGATTTTATCTTCTATTGGAGAACCTTGTGCGATTATCGGTTTAGGTGGTGGATGCACGTTAGATGTTGCCAA
AGCGGTATCGAATCTCATTCCAAATGGGGGCAGATCAGAAGATTATCAAGGTTGGGATTTATTAAAAAAACCAGGGATTT
TTAAAGTTGGAATTCCTACTTTATCTGGTACGGGAGCAGAAGCTTCTCGTACTTGTGTTCTCATGAATTTGAAAAAAAAT
CTTAAACTTGGGATGAATAGCGAATTTACTATTTATGATCAGCTCATTTTAGATCCTGAGCTAACTGCTACTGTTCCAAG
AGACCAGTATTTTTATACAGGGATGGATACCTACATTCATTGTATAGAGTCTTTAAATGGAAGCTATCGTCATCCTGTCG
GAGATGCATTTTCTCGAGAAGCGTTGGAACTCTGTAGAGAGGTTTTTCTCTCCGATGATATGATGTCGGGCGAAAATAGA
AAAAAACTTATGGTGGCTTCTTATTTAGGTGGTTGCGCGATTGCGAACAGCTACGTTGGAGTGGTTCATCCTTTTTCAGC
CGGGTTGAGTGTAGTATTAGGAACTCATCATTGCATTTCCAATTGTATAGTTATGAATCAAATGAGCGAATTTTATCCAA
AAGAAACGGATGAATTTCACTTTATGATGGATAAGCAAAAAATCAACCTTCCGAAAGGAATTTGTTCTTCATTGGATGAT
TCTCAGATGGAAAGGTTACATTTGTCTACTGTAATTCATGAAAAACCATTAACAAATGCGTTGGGAAGCGATTTTAAAAA
CATTCTCACTCAAGAAAAAACTAGATCGATCTTTTCCTCGTTTTGA

Upstream 100 bases:

>100_bases
GCGTTTGAGGATTTTTTGCGGAAAATAAATGCTTTAAAATAGATTTTACTGTATCGTTTAGTTTTATTTAATTTTTAAAA
GAGGCTTTGGTTTTTAGAAT

Downstream 100 bases:

>100_bases
AATGATGAAAAAAGCTCCAACAGTTTCCGTTATCGTCGCTGCATTTAATCAAGAGAAGTATATTGGAAGATGTATTCGCT
CTCTATTGAATCAAAATTTT

Product: alcohol dehyodrogenase

Products: NA

Alternate protein names: MEDH [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSIDLPNSKNVLQYVFGDGALKSLNKILKPKREKNTNAVFFIDIYFKDKNIISSLPLEKEDLVFYYDSAHEPKTDYIDEL
RDQILSSIGEPCAIIGLGGGCTLDVAKAVSNLIPNGGRSEDYQGWDLLKKPGIFKVGIPTLSGTGAEASRTCVLMNLKKN
LKLGMNSEFTIYDQLILDPELTATVPRDQYFYTGMDTYIHCIESLNGSYRHPVGDAFSREALELCREVFLSDDMMSGENR
KKLMVASYLGGCAIANSYVGVVHPFSAGLSVVLGTHHCISNCIVMNQMSEFYPKETDEFHFMMDKQKINLPKGICSSLDD
SQMERLHLSTVIHEKPLTNALGSDFKNILTQEKTRSIFSSF

Sequences:

>Translated_361_residues
MSIDLPNSKNVLQYVFGDGALKSLNKILKPKREKNTNAVFFIDIYFKDKNIISSLPLEKEDLVFYYDSAHEPKTDYIDEL
RDQILSSIGEPCAIIGLGGGCTLDVAKAVSNLIPNGGRSEDYQGWDLLKKPGIFKVGIPTLSGTGAEASRTCVLMNLKKN
LKLGMNSEFTIYDQLILDPELTATVPRDQYFYTGMDTYIHCIESLNGSYRHPVGDAFSREALELCREVFLSDDMMSGENR
KKLMVASYLGGCAIANSYVGVVHPFSAGLSVVLGTHHCISNCIVMNQMSEFYPKETDEFHFMMDKQKINLPKGICSSLDD
SQMERLHLSTVIHEKPLTNALGSDFKNILTQEKTRSIFSSF
>Mature_360_residues
SIDLPNSKNVLQYVFGDGALKSLNKILKPKREKNTNAVFFIDIYFKDKNIISSLPLEKEDLVFYYDSAHEPKTDYIDELR
DQILSSIGEPCAIIGLGGGCTLDVAKAVSNLIPNGGRSEDYQGWDLLKKPGIFKVGIPTLSGTGAEASRTCVLMNLKKNL
KLGMNSEFTIYDQLILDPELTATVPRDQYFYTGMDTYIHCIESLNGSYRHPVGDAFSREALELCREVFLSDDMMSGENRK
KLMVASYLGGCAIANSYVGVVHPFSAGLSVVLGTHHCISNCIVMNQMSEFYPKETDEFHFMMDKQKINLPKGICSSLDDS
QMERLHLSTVIHEKPLTNALGSDFKNILTQEKTRSIFSSF

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI48994951, Length=204, Percent_Identity=26.9607843137255, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082107, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321181, Length=199, Percent_Identity=27.6381909547739, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.244 [H]

Molecular weight: Translated: 40282; Mature: 40150

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDLPNSKNVLQYVFGDGALKSLNKILKPKREKNTNAVFFIDIYFKDKNIISSLPLEKE
CCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCHHHHHCCCCCC
DLVFYYDSAHEPKTDYIDELRDQILSSIGEPCAIIGLGGGCTLDVAKAVSNLIPNGGRSE
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCC
DYQGWDLLKKPGIFKVGIPTLSGTGAEASRTCVLMNLKKNLKLGMNSEFTIYDQLILDPE
CCCCCHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEHEEECCC
LTATVPRDQYFYTGMDTYIHCIESLNGSYRHPVGDAFSREALELCREVFLSDDMMSGENR
CEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
KKLMVASYLGGCAIANSYVGVVHPFSAGLSVVLGTHHCISNCIVMNQMSEFYPKETDEFH
CEEEHHHHHCCHHHHCCCCEEECCHHCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCEE
FMMDKQKINLPKGICSSLDDSQMERLHLSTVIHEKPLTNALGSDFKNILTQEKTRSIFSS
EEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
F
C
>Mature Secondary Structure 
SIDLPNSKNVLQYVFGDGALKSLNKILKPKREKNTNAVFFIDIYFKDKNIISSLPLEKE
CCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCHHHHHCCCCCC
DLVFYYDSAHEPKTDYIDELRDQILSSIGEPCAIIGLGGGCTLDVAKAVSNLIPNGGRSE
CEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCC
DYQGWDLLKKPGIFKVGIPTLSGTGAEASRTCVLMNLKKNLKLGMNSEFTIYDQLILDPE
CCCCCHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEHEEECCC
LTATVPRDQYFYTGMDTYIHCIESLNGSYRHPVGDAFSREALELCREVFLSDDMMSGENR
CEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
KKLMVASYLGGCAIANSYVGVVHPFSAGLSVVLGTHHCISNCIVMNQMSEFYPKETDEFH
CEEEHHHHHCCHHHHCCCCEEECCHHCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCEE
FMMDKQKINLPKGICSSLDDSQMERLHLSTVIHEKPLTNALGSDFKNILTQEKTRSIFSS
EEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1644761; 1995642 [H]