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The map label for this gene is caiD [C]

Identifier: 114799557

GI number: 114799557

Start: 996564

End: 997409

Strand: Reverse

Name: caiD [C]

Synonym: HNE_0981

Alternate gene names: 114799557

Gene position: 997409-996564 (Counterclockwise)

Preceding gene: 114798560

Following gene: 114798323

Centisome position: 26.92

GC content: 61.47

Gene sequence:

>846_bases
ATGCTGAAAGACACATACGAAGCCTTCAAGGTGACCATCGAAGACAAGGTCGCCCACATCCAGATGTCGCGCCCCGAGGC
GATGAACACGATGAACAAGGCGTTCTGGAACGAACTGCCCGAAATCGTCCGCACCATCGACAATAACGCGCTGGCCCGCG
TCATCGTCATTTCCTCCACCGGCAAGCATTTCTCTGCTGGGATGGATACGTCCGTCTTCACCACGCCCCGCCCCGCCGCC
GATCATGACCGCTTCGTGATGGCCGAGGCCTTCCGACTGAACGTGAAGGCCATCCAGTCCTCCTTCAACTGCATGGAAGA
AGCCCGCGTGCCGGTCCTCTTCGCCTGCCACGGCGCAGTCATCGGCGGCGCCATCGACATGATCACCGCCGGCGACATCC
GCTGGTGCACCAAAGACGCCTATTTCTGCATCATGGAAATCAACATCGCGATGACCGCCGATGTCGGCACCTTCCCGCGC
CTCCAGCGCTACATCCCCGAAGGCTGGGTGAAAGAACTCGCCTATACCGGCCGCAAGATCGATGCTGCCAAGGCCAAGGA
AATCGGCCTGGTGAACGACATCTACGACACCCATGAAGAGCTCATCGCCGGCGTCATGGCCACGGCCCGCGAGATCGCCT
CGAAAAACCCCCTCGCCGTCACCGGCTCCAAGGTCCTCATCAATTACGGCCGCGACCACACCACCGCCGAAACGCTCGAC
TATATCGGCCTCTGGAACACCGCCATGTTCCCCCCGCCGCACATGGCCGAAGCCTTTGCCGCCCGCGCCGAAAAACGCGA
GCCGGTCTTCCCCGACCTCGCCCCCGTCCGTACAGAGCCTATGTAA

Upstream 100 bases:

>100_bases
CGCCCGGTAAAAGCCGAAGCGGTAAAGCCTTAGCGCCGCGTCACCCCTCGCCGCGCCGCGTCTGCCTGCTACACTCCTCC
CCAACCGGAGGAGACACCCC

Downstream 100 bases:

>100_bases
CAAAAAAAGCCCCCTCCTCGGAGGGGGCTTTTTCTTTTCTGGCGAAAGGATCAGCCCTTCACCACCTCAAAATCCGTCCA
GTCCGGCGTGCGCGTCTCTT

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MLKDTYEAFKVTIEDKVAHIQMSRPEAMNTMNKAFWNELPEIVRTIDNNALARVIVISSTGKHFSAGMDTSVFTTPRPAA
DHDRFVMAEAFRLNVKAIQSSFNCMEEARVPVLFACHGAVIGGAIDMITAGDIRWCTKDAYFCIMEINIAMTADVGTFPR
LQRYIPEGWVKELAYTGRKIDAAKAKEIGLVNDIYDTHEELIAGVMATAREIASKNPLAVTGSKVLINYGRDHTTAETLD
YIGLWNTAMFPPPHMAEAFAARAEKREPVFPDLAPVRTEPM

Sequences:

>Translated_281_residues
MLKDTYEAFKVTIEDKVAHIQMSRPEAMNTMNKAFWNELPEIVRTIDNNALARVIVISSTGKHFSAGMDTSVFTTPRPAA
DHDRFVMAEAFRLNVKAIQSSFNCMEEARVPVLFACHGAVIGGAIDMITAGDIRWCTKDAYFCIMEINIAMTADVGTFPR
LQRYIPEGWVKELAYTGRKIDAAKAKEIGLVNDIYDTHEELIAGVMATAREIASKNPLAVTGSKVLINYGRDHTTAETLD
YIGLWNTAMFPPPHMAEAFAARAEKREPVFPDLAPVRTEPM
>Mature_281_residues
MLKDTYEAFKVTIEDKVAHIQMSRPEAMNTMNKAFWNELPEIVRTIDNNALARVIVISSTGKHFSAGMDTSVFTTPRPAA
DHDRFVMAEAFRLNVKAIQSSFNCMEEARVPVLFACHGAVIGGAIDMITAGDIRWCTKDAYFCIMEINIAMTADVGTFPR
LQRYIPEGWVKELAYTGRKIDAAKAKEIGLVNDIYDTHEELIAGVMATAREIASKNPLAVTGSKVLINYGRDHTTAETLD
YIGLWNTAMFPPPHMAEAFAARAEKREPVFPDLAPVRTEPM

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=267, Percent_Identity=38.5767790262172, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI194097323, Length=263, Percent_Identity=25.8555133079848, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI221142681, Length=270, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082183, Length=269, Percent_Identity=25.2788104089219, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788682, Length=218, Percent_Identity=27.0642201834862, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787659, Length=260, Percent_Identity=22.3076923076923, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790281, Length=199, Percent_Identity=23.6180904522613, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=278, Percent_Identity=32.7338129496403, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17536985, Length=267, Percent_Identity=29.2134831460674, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=26.2548262548263, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=230, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=25.1968503937008, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920382, Length=261, Percent_Identity=37.5478927203065, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=28.2442748091603, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI20129971, Length=260, Percent_Identity=23.8461538461538, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653477, Length=260, Percent_Identity=23.8461538461538, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31248; Mature: 31248

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDTYEAFKVTIEDKVAHIQMSRPEAMNTMNKAFWNELPEIVRTIDNNALARVIVISST
CCCCCCHHHEEEEEHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
GKHFSAGMDTSVFTTPRPAADHDRFVMAEAFRLNVKAIQSSFNCMEEARVPVLFACHGAV
CCCCCCCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
IGGAIDMITAGDIRWCTKDAYFCIMEINIAMTADVGTFPRLQRYIPEGWVKELAYTGRKI
HCCHHHEEECCCCEEECCCCEEEEEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHCCCCC
DAAKAKEIGLVNDIYDTHEELIAGVMATAREIASKNPLAVTGSKVLINYGRDHTTAETLD
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCHHHHHH
YIGLWNTAMFPPPHMAEAFAARAEKREPVFPDLAPVRTEPM
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKDTYEAFKVTIEDKVAHIQMSRPEAMNTMNKAFWNELPEIVRTIDNNALARVIVISST
CCCCCCHHHEEEEEHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
GKHFSAGMDTSVFTTPRPAADHDRFVMAEAFRLNVKAIQSSFNCMEEARVPVLFACHGAV
CCCCCCCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
IGGAIDMITAGDIRWCTKDAYFCIMEINIAMTADVGTFPRLQRYIPEGWVKELAYTGRKI
HCCHHHEEECCCCEEECCCCEEEEEEEEEEEEECCCCHHHHHHHCCHHHHHHHHHCCCCC
DAAKAKEIGLVNDIYDTHEELIAGVMATAREIASKNPLAVTGSKVLINYGRDHTTAETLD
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCHHHHHH
YIGLWNTAMFPPPHMAEAFAARAEKREPVFPDLAPVRTEPM
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA