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The map label for this gene is gpsA

Identifier: 114798560

GI number: 114798560

Start: 997477

End: 998487

Strand: Reverse

Name: gpsA

Synonym: HNE_0982

Alternate gene names: 114798560

Gene position: 998487-997477 (Counterclockwise)

Preceding gene: 114797538

Following gene: 114799557

Centisome position: 26.95

GC content: 68.45

Gene sequence:

>1011_bases
ATGACACAGCACTTCAAGACATTCGGCGTCATCGGCGCGGGCGCCTGGGGCACAGCCATCGCGCAGATGCTGGCCCGCGA
AGGCCAGACCGTGCATCTCTGGGCGCTCGAGCCCGAGGTCGCCGCCGCCATCAACACCGCCCGCGAGAACACCGCCTTCC
TCAAAGGCGTGCCCCTGAAGCCGGAAATCCGCGCCACCAACAAGCTGGAAGACCTTGGCCTCGCCGACGCCATCTTCGCC
GTCGCCCCCGCCCAGCACACCCGCACAACCCTGCGCGCCCTGCGCGCCAGCCTGCGTCCCGGCACGCCCGTCGTCCTCTG
CTCCAAGGGCATCGAACTCGCCACCGGCGAATTCATGACCCAGGTTCTGAAGGATGAGCTTCCCGAAGCCATCCCCGCCG
TCATGTCCGGCCCCAGCTTCGCCATCGACGTCGCCAAGGGCCTGCCCACCGCGGTCACCCTCGCCATCGAAGATACCCGC
CTCGGCACAGAGCTGATCCAGGCCATCTCCACGCCCACCTTCCGGCCCTATCTGGGTACGGACCTTCTGGGGGCGGAAGT
CGGCGGCTCGGTGAAAAACGTCCTCGCCATCGCCTGCGGCATCGCGCTCGGCAAGGGCCTCGGCCGCTCCGCCCATGCCG
CCCTCATCGCACGCGGCTATGCCGAGATGACCCGCCTCGCCCTGACGCTGGGCGCAGAGGCGGAAACCCTCACCGGCCTC
TCCGGCCTCGGCGATCTCGTGCTCACCTGCTCGTCGGAAACCAGCCGCAACATGTCCCTCGGCCTCGCGCTCGGCAAAGG
CGAAACCCTCGCCAGCATCCTCGCCGCCCGCAACGCCGTGACCGAAGGCGTTGCCACCGCCCCGGTCCTGCGCCGCCTCG
CCCGCAGCCAGGGCATCGAAATGCCCATCTGCGAAGCCGTCGCCGCCGTCATCGAAGGCGAAATCACCGTGGATGACGCC
ATCACCGCCCTCCTGATGCGCCCGGTAAAAGCCGAAGCGGTAAAGCCTTAG

Upstream 100 bases:

>100_bases
TGCCCTCGTCTCCCACCTGACATTGCAGGTATTGCCGTTTGCGCAGCGTCCGTCAATCGGGCCGCTTGCCCCCCGCCCCG
GCTTCGGCCAAAACCGGCCC

Downstream 100 bases:

>100_bases
CGCCGCGTCACCCCTCGCCGCGCCGCGTCTGCCTGCTACACTCCTCCCCAACCGGAGGAGACACCCCATGCTGAAAGACA
CATACGAAGCCTTCAAGGTG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTQHFKTFGVIGAGAWGTAIAQMLAREGQTVHLWALEPEVAAAINTARENTAFLKGVPLKPEIRATNKLEDLGLADAIFA
VAPAQHTRTTLRALRASLRPGTPVVLCSKGIELATGEFMTQVLKDELPEAIPAVMSGPSFAIDVAKGLPTAVTLAIEDTR
LGTELIQAISTPTFRPYLGTDLLGAEVGGSVKNVLAIACGIALGKGLGRSAHAALIARGYAEMTRLALTLGAEAETLTGL
SGLGDLVLTCSSETSRNMSLGLALGKGETLASILAARNAVTEGVATAPVLRRLARSQGIEMPICEAVAAVIEGEITVDDA
ITALLMRPVKAEAVKP

Sequences:

>Translated_336_residues
MTQHFKTFGVIGAGAWGTAIAQMLAREGQTVHLWALEPEVAAAINTARENTAFLKGVPLKPEIRATNKLEDLGLADAIFA
VAPAQHTRTTLRALRASLRPGTPVVLCSKGIELATGEFMTQVLKDELPEAIPAVMSGPSFAIDVAKGLPTAVTLAIEDTR
LGTELIQAISTPTFRPYLGTDLLGAEVGGSVKNVLAIACGIALGKGLGRSAHAALIARGYAEMTRLALTLGAEAETLTGL
SGLGDLVLTCSSETSRNMSLGLALGKGETLASILAARNAVTEGVATAPVLRRLARSQGIEMPICEAVAAVIEGEITVDDA
ITALLMRPVKAEAVKP
>Mature_335_residues
TQHFKTFGVIGAGAWGTAIAQMLAREGQTVHLWALEPEVAAAINTARENTAFLKGVPLKPEIRATNKLEDLGLADAIFAV
APAQHTRTTLRALRASLRPGTPVVLCSKGIELATGEFMTQVLKDELPEAIPAVMSGPSFAIDVAKGLPTAVTLAIEDTRL
GTELIQAISTPTFRPYLGTDLLGAEVGGSVKNVLAIACGIALGKGLGRSAHAALIARGYAEMTRLALTLGAEAETLTGLS
GLGDLVLTCSSETSRNMSLGLALGKGETLASILAARNAVTEGVATAPVLRRLARSQGIEMPICEAVAAVIEGEITVDDAI
TALLMRPVKAEAVKP

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=26.9340974212034, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24307999, Length=344, Percent_Identity=24.7093023255814, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790037, Length=335, Percent_Identity=40, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17507425, Length=278, Percent_Identity=26.978417266187, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32564399, Length=354, Percent_Identity=25.1412429378531, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=24.8603351955307, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=24.8603351955307, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=27.1676300578035, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320181, Length=337, Percent_Identity=27.0029673590504, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136204, Length=342, Percent_Identity=25.4385964912281, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136200, Length=342, Percent_Identity=25.4385964912281, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136202, Length=342, Percent_Identity=25.4385964912281, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI22026922, Length=340, Percent_Identity=24.1176470588235, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45551945, Length=282, Percent_Identity=26.9503546099291, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281362270, Length=282, Percent_Identity=26.9503546099291, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648969, Length=275, Percent_Identity=26.1818181818182, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_HYPNA (Q0C3I7)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759706.1
- ProteinModelPortal:   Q0C3I7
- SMR:   Q0C3I7
- STRING:   Q0C3I7
- GeneID:   4287404
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0982
- NMPDR:   fig|228405.5.peg.957
- TIGR:   HNE_0982
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- PhylomeDB:   Q0C3I7
- ProtClustDB:   PRK00094
- BioCyc:   HNEP81032:HNE_0982-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34804; Mature: 34673

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 109-109 BINDING 109-109 BINDING 141-141 BINDING 256-256 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHFKTFGVIGAGAWGTAIAQMLAREGQTVHLWALEPEVAAAINTARENTAFLKGVPLK
CCCCCCHHEEEECCHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCHHHCCCCCC
PEIRATNKLEDLGLADAIFAVAPAQHTRTTLRALRASLRPGTPVVLCSKGIELATGEFMT
CCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
QVLKDELPEAIPAVMSGPSFAIDVAKGLPTAVTLAIEDTRLGTELIQAISTPTFRPYLGT
HHHHHHHHHHHHHHHCCCCEEEEHHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCCCC
DLLGAEVGGSVKNVLAIACGIALGKGLGRSAHAALIARGYAEMTRLALTLGAEAETLTGL
CHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
SGLGDLVLTCSSETSRNMSLGLALGKGETLASILAARNAVTEGVATAPVLRRLARSQGIE
CCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPICEAVAAVIEGEITVDDAITALLMRPVKAEAVKP
CHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
TQHFKTFGVIGAGAWGTAIAQMLAREGQTVHLWALEPEVAAAINTARENTAFLKGVPLK
CCCCCHHEEEECCHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCHHHCCCCCC
PEIRATNKLEDLGLADAIFAVAPAQHTRTTLRALRASLRPGTPVVLCSKGIELATGEFMT
CCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
QVLKDELPEAIPAVMSGPSFAIDVAKGLPTAVTLAIEDTRLGTELIQAISTPTFRPYLGT
HHHHHHHHHHHHHHHCCCCEEEEHHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCCCC
DLLGAEVGGSVKNVLAIACGIALGKGLGRSAHAALIARGYAEMTRLALTLGAEAETLTGL
CHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
SGLGDLVLTCSSETSRNMSLGLALGKGETLASILAARNAVTEGVATAPVLRRLARSQGIE
CCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPICEAVAAVIEGEITVDDAITALLMRPVKAEAVKP
CHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA