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The map label for this gene is ruvA [H]

Identifier: 114798884

GI number: 114798884

Start: 129409

End: 130032

Strand: Direct

Name: ruvA [H]

Synonym: HNE_0146

Alternate gene names: 114798884

Gene position: 129409-130032 (Clockwise)

Preceding gene: 114799962

Following gene: 114800414

Centisome position: 3.49

GC content: 65.38

Gene sequence:

>624_bases
ATGATTATAGGTCGTCTCAAGGGCGAGGTTGCGGCCATCGGGCTCGACCATGTGCTGATTGACGTAAACGGGGTGGGCTA
TGTCGCCCTCGCGGGAACGCGCCTCCTGGCAAGGCTGCAGACGGGCGACGCGATCACCGCGCATATCGAAACGCGCGTGA
CCGAAAGCTCGATCACCCTCTTTGCCTTCGCCACCGATGAAGAGCGCGCCTGGTTCGTGCGCCTTCAGGATGTGCCGGGC
GTTGCCGGAAAGTCCGCCCTCGCCATTCTCGACGGGCTTTCCCCGGCTGACATCATGGATGCCATCGCGCTGGGCGATGC
GGGCGCCTTCACCCGCGCCAAGGGTATCGGCAAGAAGCTCGGGGAACGGATCGTTACCGAGCTGGCCGGCAAGGCGCCTC
CTCTGGGACGGTTTGGCAAATTTGAAGTGGCCGCTGTTGCGGGCCTTGCCTCTGCCCAGCCGGCCTCGGCAGCCACCGGC
GCACGGGGCGAAGCGGTCAGCGCGCTGGTCAATCTCGGTTATTCGCAGAGCGAGGCCGCCAGGGCTGTGGCGGCGGCGGC
CAAGAACGGGGCTGAAGAAGTTGGCGCGCTGGTCAAAGGCGCGCTGAAGGAACTGGCCAGATGA

Upstream 100 bases:

>100_bases
TTCCCAGGGCAGGGGAGATGAAGCTCGACGCCGCCGACGCGCTTGCCTGCGCCATCTGCGCGGCGCACCATCTGCCGCTG
CAGATGAAGCGGGGCGCGGC

Downstream 100 bases:

>100_bases
GCCGCGAGGGCGCCCTCTCCGATCCCAACGCCCAAGGCGGGGATGCGCTCGACCGCGCCCTCCGCCCACAGACGTTTGAG
GATTATGTTGGCCAACGCAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIIGRLKGEVAAIGLDHVLIDVNGVGYVALAGTRLLARLQTGDAITAHIETRVTESSITLFAFATDEERAWFVRLQDVPG
VAGKSALAILDGLSPADIMDAIALGDAGAFTRAKGIGKKLGERIVTELAGKAPPLGRFGKFEVAAVAGLASAQPASAATG
ARGEAVSALVNLGYSQSEAARAVAAAAKNGAEEVGALVKGALKELAR

Sequences:

>Translated_207_residues
MIIGRLKGEVAAIGLDHVLIDVNGVGYVALAGTRLLARLQTGDAITAHIETRVTESSITLFAFATDEERAWFVRLQDVPG
VAGKSALAILDGLSPADIMDAIALGDAGAFTRAKGIGKKLGERIVTELAGKAPPLGRFGKFEVAAVAGLASAQPASAATG
ARGEAVSALVNLGYSQSEAARAVAAAAKNGAEEVGALVKGALKELAR
>Mature_207_residues
MIIGRLKGEVAAIGLDHVLIDVNGVGYVALAGTRLLARLQTGDAITAHIETRVTESSITLFAFATDEERAWFVRLQDVPG
VAGKSALAILDGLSPADIMDAIALGDAGAFTRAKGIGKKLGERIVTELAGKAPPLGRFGKFEVAAVAGLASAQPASAATG
ARGEAVSALVNLGYSQSEAARAVAAAAKNGAEEVGALVKGALKELAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=36.2745098039216, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20971; Mature: 20971

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGRLKGEVAAIGLDHVLIDVNGVGYVALAGTRLLARLQTGDAITAHIETRVTESSITL
CEECCCCCCEEEEEEEEEEEEECCCEEEEHHHHHHHHHHCCCCEEEEEEEEEEECCCEEE
FAFATDEERAWFVRLQDVPGVAGKSALAILDGLSPADIMDAIALGDAGAFTRAKGIGKKL
EEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
GERIVTELAGKAPPLGRFGKFEVAAVAGLASAQPASAATGARGEAVSALVNLGYSQSEAA
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
RAVAAAAKNGAEEVGALVKGALKELAR
HHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIGRLKGEVAAIGLDHVLIDVNGVGYVALAGTRLLARLQTGDAITAHIETRVTESSITL
CEECCCCCCEEEEEEEEEEEEECCCEEEEHHHHHHHHHHCCCCEEEEEEEEEEECCCEEE
FAFATDEERAWFVRLQDVPGVAGKSALAILDGLSPADIMDAIALGDAGAFTRAKGIGKKL
EEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
GERIVTELAGKAPPLGRFGKFEVAAVAGLASAQPASAATGARGEAVSALVNLGYSQSEAA
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
RAVAAAAKNGAEEVGALVKGALKELAR
HHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA