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The map label for this gene is pdxA [H]

Identifier: 114798861

GI number: 114798861

Start: 2240235

End: 2241242

Strand: Direct

Name: pdxA [H]

Synonym: HNE_2151

Alternate gene names: 114798861

Gene position: 2240235-2241242 (Clockwise)

Preceding gene: 114797858

Following gene: 114799371

Centisome position: 60.46

GC content: 65.87

Gene sequence:

>1008_bases
GTGACCTCGCCTTCCCTCCTTCCTCTGGCCCTAACCATGGGCGACCCTGCCGGATGCGGACCTCAGATCACGGCCGCTGC
CTGGCACGCGCTCAAGGATAATCCCGCCAGCGCGTTCTATGTTGTTGGCTGGCCGGGACTTTACTGCGGCGCCCCCACTG
AAGTGATCGCTTCACCGGGCGATGCGGCGCGCGTGTTCTCTCGCGCGCTGCCCGTGCTGGCGCGGGGCGATGCGCGCCCT
GTGACACCGGGAAAACCTGATCCGGACACAGCGGCAGGCATTATCACGTCCATCGAAACGGCGACCGCCCATGCGCTGGC
GGGCATCGCCGGCGCGGTTGTCACCAATCCCATTCACAAGGCGCTGCTCTACGGTCAGGGCTTTCGCTTTCCCGGCCATA
CGGAATTCATCGCCAGCCTTTGCGCGACAGATGGCGGCGCGGCGCCCGAACCTGTCATGATGCTGACCGGCGGCGGGCTC
CGCGTGGCACTGGCAACAATCCACATGCCTTACACCGCTGTTCCCGCCGCGCTGGCTGATGGCCGCTTGCAGCGCATCGC
CCGTATCACGGCGGCAGCGCTGACACGCCAGTTCGGCATTCCTGCCCCGCGCATTGCCTTCACCGGCCTCAACCCTCACG
CAGGAGAGGACGGCACAATCGGACGCGAAGAGGTGGAGATCATCAACCCGGCCGCTGCCGAGCTGCGCAATGAGGGCCTC
GACATCTCGGACGCCCGGCCAGGCGATACCGTTTTTGCCGAGGCGTTGGGTGGCCGTTTCGACGCCGTGATCGCCATGAC
CCATGATCAGGGCCTCATACCGGTCAAGACACTGGACATGTGGGGCGGCGTGAACACAACGCTGGGCCTGCCGATCATCC
GCACGAGCCCGGACCATGGCACAGCCTATGACGCAGCCGCCGCCGGAACGGCCAAGGCCGATAGCCTGATCGCCGCCATT
CATTCTGCGCGGGAACAAGCCGCCAATTGGGCGAGGAGCCCCACATGA

Upstream 100 bases:

>100_bases
GCGGGAACTGCGCAATGCTCGCCGCCTGGCGACCATCATCTACCGCTAGGACAGGCGATTCCGCTTGATCCGCTGCGCGA
TTGGCGCGACACCCCCGCGC

Downstream 100 bases:

>100_bases
ACAACGACCATGACTATGGCGACGACAACGGCAGTCACCCGGCGCTGACCGATGCCCCCGCCCGCAAGGCGCTGGGCCAG
CACTTTCTGTTCGATCCCAG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTSPSLLPLALTMGDPAGCGPQITAAAWHALKDNPASAFYVVGWPGLYCGAPTEVIASPGDAARVFSRALPVLARGDARP
VTPGKPDPDTAAGIITSIETATAHALAGIAGAVVTNPIHKALLYGQGFRFPGHTEFIASLCATDGGAAPEPVMMLTGGGL
RVALATIHMPYTAVPAALADGRLQRIARITAAALTRQFGIPAPRIAFTGLNPHAGEDGTIGREEVEIINPAAAELRNEGL
DISDARPGDTVFAEALGGRFDAVIAMTHDQGLIPVKTLDMWGGVNTTLGLPIIRTSPDHGTAYDAAAAGTAKADSLIAAI
HSAREQAANWARSPT

Sequences:

>Translated_335_residues
MTSPSLLPLALTMGDPAGCGPQITAAAWHALKDNPASAFYVVGWPGLYCGAPTEVIASPGDAARVFSRALPVLARGDARP
VTPGKPDPDTAAGIITSIETATAHALAGIAGAVVTNPIHKALLYGQGFRFPGHTEFIASLCATDGGAAPEPVMMLTGGGL
RVALATIHMPYTAVPAALADGRLQRIARITAAALTRQFGIPAPRIAFTGLNPHAGEDGTIGREEVEIINPAAAELRNEGL
DISDARPGDTVFAEALGGRFDAVIAMTHDQGLIPVKTLDMWGGVNTTLGLPIIRTSPDHGTAYDAAAAGTAKADSLIAAI
HSAREQAANWARSPT
>Mature_334_residues
TSPSLLPLALTMGDPAGCGPQITAAAWHALKDNPASAFYVVGWPGLYCGAPTEVIASPGDAARVFSRALPVLARGDARPV
TPGKPDPDTAAGIITSIETATAHALAGIAGAVVTNPIHKALLYGQGFRFPGHTEFIASLCATDGGAAPEPVMMLTGGGLR
VALATIHMPYTAVPAALADGRLQRIARITAAALTRQFGIPAPRIAFTGLNPHAGEDGTIGREEVEIINPAAAELRNEGLD
ISDARPGDTVFAEALGGRFDAVIAMTHDQGLIPVKTLDMWGGVNTTLGLPIIRTSPDHGTAYDAAAAGTAKADSLIAAIH
SAREQAANWARSPT

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=260, Percent_Identity=40.3846153846154, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34306; Mature: 34175

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSLLPLALTMGDPAGCGPQITAAAWHALKDNPASAFYVVGWPGLYCGAPTEVIASPG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCEECCCCHHHHCCCC
DAARVFSRALPVLARGDARPVTPGKPDPDTAAGIITSIETATAHALAGIAGAVVTNPIHK
HHHHHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLYGQGFRFPGHTEFIASLCATDGGAAPEPVMMLTGGGLRVALATIHMPYTAVPAALAD
HHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEEEECCHHHHHHHHHH
GRLQRIARITAAALTRQFGIPAPRIAFTGLNPHAGEDGTIGREEVEIINPAAAELRNEGL
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHEEECHHHHHHHHCCC
DISDARPGDTVFAEALGGRFDAVIAMTHDQGLIPVKTLDMWGGVNTTLGLPIIRTSPDHG
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEEEHHHCCCCCCCCCCEEEEECCCCC
TAYDAAAAGTAKADSLIAAIHSAREQAANWARSPT
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSPSLLPLALTMGDPAGCGPQITAAAWHALKDNPASAFYVVGWPGLYCGAPTEVIASPG
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCEECCCCHHHHCCCC
DAARVFSRALPVLARGDARPVTPGKPDPDTAAGIITSIETATAHALAGIAGAVVTNPIHK
HHHHHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLYGQGFRFPGHTEFIASLCATDGGAAPEPVMMLTGGGLRVALATIHMPYTAVPAALAD
HHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEEEECCHHHHHHHHHH
GRLQRIARITAAALTRQFGIPAPRIAFTGLNPHAGEDGTIGREEVEIINPAAAELRNEGL
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHEEECHHHHHHHHCCC
DISDARPGDTVFAEALGGRFDAVIAMTHDQGLIPVKTLDMWGGVNTTLGLPIIRTSPDHG
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEEEHHHCCCCCCCCCCEEEEECCCCC
TAYDAAAAGTAKADSLIAAIHSAREQAANWARSPT
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA