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The map label for this gene is qor [H]

Identifier: 114798574

GI number: 114798574

Start: 3476925

End: 3477914

Strand: Reverse

Name: qor [H]

Synonym: HNE_3323

Alternate gene names: 114798574

Gene position: 3477914-3476925 (Counterclockwise)

Preceding gene: 114799135

Following gene: 114799170

Centisome position: 93.87

GC content: 62.53

Gene sequence:

>990_bases
ATGAAAGCCGTATTGTCGAAAGTGGTCGGTGGACCAGAGACGCTCGTGATCGAGGATGTGGCGGTGCCAACCCCCGGCAA
GGGTCAGGTTCTGGTGCAGGTCAAAGCCTGCGGGGTGAACTATCCTGACGTTCTGATCATTCAGGACATGTACCAGTTCA
AGCCGCCGCGCCCGTTCTCTCCGGGCGGGGAAGTGGCCGGAATTGTCTCCGCCGTGGGCGAGGGTGTCTCGCATGTAAAG
CCGGGCGACCGGGTGCTGGCCTCGACCGGTAATGGCGGGATGGCAGAATACTGCCTGGCGGCGGCGCATGGCGTGATGCC
GATCCCTGAAGGGATGCCGTTTGAAGAGGCGGCCGCATTCCTGATGACCTATGGCACCTCCTATTACGCCATCAAGGACC
GGGGCGATCCAAAGCCCGGCGAGAAGCTGCTCGTCCTTGGCGCCGCTGGCGGCGTTGGCATTGCGGCGGTTGAGCTCGGC
AAGGCGATGGGCCTGGAAGTGATCGCGGCGGCTTCAAGCCAGGAGAAGGTGGATTTCTGCCTTTCCAAGGGCGCCGACCA
TGGCCTCGTCTATGCGCGGGAACTTGACCGCGACGGGCAGAAGAAATTCTCCGACGACATCAAGGCCGTTTCCGGTGGCG
GCGTCGACATCATCTATGACGGCGTGGGCGGCAATTATGCCGAGCCGGCTGTGCGGGCGATGAACTGGGAAGGGCGTTTC
CTCGTCATCGGCTTCCCGGCGGGCATTCCGAAACTGCCGCTGAACCTGACGCTGCTGAAAAGCTGCGATGTGCGCGGCGT
GTTCTGGGGCGCGGCGGTTGCGCGTGATCCCAAAGCCCACCAGCAGAACGTCAAGGAACTCTTTGACCTCTACAAGGCCG
GCAAGATCCGCCCGCACATTTCGGGCTCCTATCCGATGGAGAAGGCGGCCGACGCGATCCGTGAACTGCAGGACCGCAAG
GCGCAGGGCAAAGTGGTTGTGACCATGTAG

Upstream 100 bases:

>100_bases
CATCGCAATGGTTCCTTTCCCCTCGCGTAAGGCTTGGCGCCTGCTCGCGGCATGGCTACCGTCTGGAAGGTGAAACAACA
AGCTTTGAAGGGAGAGGCAT

Downstream 100 bases:

>100_bases
GCCAGCAGTTTTGCCCGGCGCAGCCCTTGGGCTGTCCGGCGAAAGTCTATCTCCCCGGTGATCCGGGGACGGAAAATTGC
TTCAAGACGTATCGGGGTGG

Product: putative quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKAVLSKVVGGPETLVIEDVAVPTPGKGQVLVQVKACGVNYPDVLIIQDMYQFKPPRPFSPGGEVAGIVSAVGEGVSHVK
PGDRVLASTGNGGMAEYCLAAAHGVMPIPEGMPFEEAAAFLMTYGTSYYAIKDRGDPKPGEKLLVLGAAGGVGIAAVELG
KAMGLEVIAAASSQEKVDFCLSKGADHGLVYARELDRDGQKKFSDDIKAVSGGGVDIIYDGVGGNYAEPAVRAMNWEGRF
LVIGFPAGIPKLPLNLTLLKSCDVRGVFWGAAVARDPKAHQQNVKELFDLYKAGKIRPHISGSYPMEKAADAIRELQDRK
AQGKVVVTM

Sequences:

>Translated_329_residues
MKAVLSKVVGGPETLVIEDVAVPTPGKGQVLVQVKACGVNYPDVLIIQDMYQFKPPRPFSPGGEVAGIVSAVGEGVSHVK
PGDRVLASTGNGGMAEYCLAAAHGVMPIPEGMPFEEAAAFLMTYGTSYYAIKDRGDPKPGEKLLVLGAAGGVGIAAVELG
KAMGLEVIAAASSQEKVDFCLSKGADHGLVYARELDRDGQKKFSDDIKAVSGGGVDIIYDGVGGNYAEPAVRAMNWEGRF
LVIGFPAGIPKLPLNLTLLKSCDVRGVFWGAAVARDPKAHQQNVKELFDLYKAGKIRPHISGSYPMEKAADAIRELQDRK
AQGKVVVTM
>Mature_329_residues
MKAVLSKVVGGPETLVIEDVAVPTPGKGQVLVQVKACGVNYPDVLIIQDMYQFKPPRPFSPGGEVAGIVSAVGEGVSHVK
PGDRVLASTGNGGMAEYCLAAAHGVMPIPEGMPFEEAAAFLMTYGTSYYAIKDRGDPKPGEKLLVLGAAGGVGIAAVELG
KAMGLEVIAAASSQEKVDFCLSKGADHGLVYARELDRDGQKKFSDDIKAVSGGGVDIIYDGVGGNYAEPAVRAMNWEGRF
LVIGFPAGIPKLPLNLTLLKSCDVRGVFWGAAVARDPKAHQQNVKELFDLYKAGKIRPHISGSYPMEKAADAIRELQDRK
AQGKVVVTM

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=333, Percent_Identity=35.7357357357357, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI13236495, Length=333, Percent_Identity=35.7357357357357, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI18379349, Length=320, Percent_Identity=32.8125, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI194239676, Length=332, Percent_Identity=33.7349397590361, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI22538446, Length=349, Percent_Identity=29.512893982808, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI22538444, Length=349, Percent_Identity=29.512893982808, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI24308257, Length=355, Percent_Identity=26.4788732394366, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI28557745, Length=331, Percent_Identity=30.2114803625378, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI67078404, Length=311, Percent_Identity=26.0450160771704, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI67078406, Length=305, Percent_Identity=25.9016393442623, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41872631, Length=253, Percent_Identity=28.4584980237154, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI156627571, Length=350, Percent_Identity=23.1428571428571, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI47519420, Length=290, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI90669511, Length=220, Percent_Identity=29.0909090909091, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI197927207, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=326, Percent_Identity=30.9815950920245, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082125, Length=370, Percent_Identity=27.2972972972973, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI226510941, Length=341, Percent_Identity=26.9794721407625, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081918, Length=328, Percent_Identity=23.4756097560976, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=331, Percent_Identity=29.9093655589124, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17536829, Length=313, Percent_Identity=26.8370607028754, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=350, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=311, Percent_Identity=27.0096463022508, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17556000, Length=320, Percent_Identity=25.9375, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71987554, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=339, Percent_Identity=30.6784660766962, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6323961, Length=313, Percent_Identity=25.8785942492013, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=315, Percent_Identity=24.7619047619048, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=260, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=319, Percent_Identity=24.1379310344828, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221330659, Length=248, Percent_Identity=28.2258064516129, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920632, Length=248, Percent_Identity=28.2258064516129, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24581345, Length=248, Percent_Identity=26.6129032258064, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI45550423, Length=307, Percent_Identity=23.7785016286645, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137530, Length=332, Percent_Identity=26.8072289156627, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34653; Mature: 34653

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLSKVVGGPETLVIEDVAVPTPGKGQVLVQVKACGVNYPDVLIIQDMYQFKPPRPFS
CHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEEEHHHHCCCCCCCC
PGGEVAGIVSAVGEGVSHVKPGDRVLASTGNGGMAEYCLAAAHGVMPIPEGMPFEEAAAF
CCCHHHHHHHHHHCCHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
LMTYGTSYYAIKDRGDPKPGEKLLVLGAAGGVGIAAVELGKAMGLEVIAAASSQEKVDFC
HHHCCCEEEEEECCCCCCCCCEEEEEECCCCCEEHHHHHHHHCCEEEEEECCCCHHHHHH
LSKGADHGLVYARELDRDGQKKFSDDIKAVSGGGVDIIYDGVGGNYAEPAVRAMNWEGRF
HHCCCCCCEEEEEHHCCCHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHCCCCCCE
LVIGFPAGIPKLPLNLTLLKSCDVRGVFWGAAVARDPKAHQQNVKELFDLYKAGKIRPHI
EEEECCCCCCCCCCCEEEEECCCCCEEEECHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
SGSYPMEKAADAIRELQDRKAQGKVVVTM
CCCCCHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MKAVLSKVVGGPETLVIEDVAVPTPGKGQVLVQVKACGVNYPDVLIIQDMYQFKPPRPFS
CHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEEEHHHHCCCCCCCC
PGGEVAGIVSAVGEGVSHVKPGDRVLASTGNGGMAEYCLAAAHGVMPIPEGMPFEEAAAF
CCCHHHHHHHHHHCCHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
LMTYGTSYYAIKDRGDPKPGEKLLVLGAAGGVGIAAVELGKAMGLEVIAAASSQEKVDFC
HHHCCCEEEEEECCCCCCCCCEEEEEECCCCCEEHHHHHHHHCCEEEEEECCCCHHHHHH
LSKGADHGLVYARELDRDGQKKFSDDIKAVSGGGVDIIYDGVGGNYAEPAVRAMNWEGRF
HHCCCCCCEEEEEHHCCCHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHCCCCCCE
LVIGFPAGIPKLPLNLTLLKSCDVRGVFWGAAVARDPKAHQQNVKELFDLYKAGKIRPHI
EEEECCCCCCCCCCCEEEEECCCCCEEEECHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
SGSYPMEKAADAIRELQDRKAQGKVVVTM
CCCCCHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]